Gene model reviewed during 5.45
There is only one protein coding transcript and one polypeptide associated with this gene
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Stam using the Feature Mapper tool.
Stam and aurB transcripts are detected in all developmental stages, but are at highest levels in embryos and adults. Stam and aurB transcripts are detected at very high levels in syncytial blastoderm embryos. From stage 7 onwards, a segmentally repeated pattern is visible for both transcripts. Expression is detected in the developing ventral nerve cord; later, a limited number of cells in the condensed nerve cord continue to express Stam and aurB transcripts. Stam and aurB transcript expression is also detected during oogenesis, starting at stage S9. In stages S9-S10, expression is high in the nurse cell cytoplasm. Transcript is detected in deposited eggs.
GBrowse - Visual display of RNA-Seq signalsView Dmel\Stam in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Stam is required for the normal clearance of the paternal mitochondrial derivatives in developing embryos.
Stam is involved in tracheal cell migration during the morphogenesis of the dorsal air sac primordium.
dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology.