Gene model reviewed during 5.44
Gene model reviewed during 5.45
None of the polypeptides share 100% sequence identity.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\I-2 using the Feature Mapper tool.
I-2 transcripts are present throughout development. Expression is weak but uniform in early embryos, and also weak and uniform in larval brains and imaginal discs. In testes, expression is detected in primary spermatocytes and is degraded shortly after meiosis.
I-2 protein is observed in embryos and female ovaries and whole adults on western blots. It is observed in both somatic and germline cells in ovaries with the highest levels in the cytoplasm of nurse cells. In later stages it appears to be transferred from the nurse cells to the oocyte.
GBrowse - Visual display of RNA-Seq signalsView Dmel\I-2 in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.