A3-3, EG:33C11.1 , dATF3
Gene model reviewed during 5.44
Stop-codon suppression (UGA) postulated; FBrf0216884.
Gene model reviewed during 5.56
Interacts with Jra/jun; the interaction enhances the DNA-binding activity of Atf3.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Atf3 using the Feature Mapper tool.
Atf3 mRNA as assayed by northen blot is expressed highly in embryos and first instar larvae, then tapers off to no expression by wandering third instar larval stage. Faint expression is again seen in pupae at 48h APF, which is increased to moderate expression in adults. Atf3 mRNA was also assayed by RT-PCR at 15 timepoints in third instar larvae and pupae, showing an early peak at 6h APF, then minimal expression until 61h APF. Tissue-specific RT-PCR showed expression in isolated integuments but not in fat body.
GBrowse - Visual display of RNA-Seq signalsView Dmel\Atf3 in GBrowse 2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for merge of: A3-3 EG:33C11.1