dMfn, Mfn, mitofusin, mfn2
target of the Yorkie pathway - regulation of mitochondrial fusion, organ size, steroid synthesis in the ring gland and ovarian follicle cell differentiation - modulates endoplasmic reticulum function, Reaper binds Marf to induce mitochondrial fragmentation
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.52
Interacts with Mul1.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Marf using the Feature Mapper tool.
Maternally-expressed Marf transcript is present in early embryos, but has degraded before blastoderm stage. Zygotic expression begins at embryonic stage 8. By stage 11,expression is primarily observed in the invaginating midgut and in the mesoderm. During germ band retraction, expression is observed in the developing gut, with strong expression in the midgut. Expression is also observed in somatic muscle and in pharyngeal muscle. In adult females, Marf is expressed in nurse cells and oocytes, but not in follicle cells. In adult males, Marf is expressed in premeiotic spermaticytes, primary spermatocytes, and early-stage spermatids.
GBrowse - Visual display of RNA-Seq signalsView Dmel\Marf in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: Marf CG3869
Source for merge of: Marf anon-WO0125274.3