FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Gene: Dmel\Wdr62
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General Information
Symbol
Dmel\Wdr62
Species
D. melanogaster
Name
WD repeat domain 62
Annotation Symbol
CG7337
Feature Type
protein_coding_gene
FlyBase ID
FBgn0031374
Gene Model Status
Current
Stock Availability
21 publicly available
Gene Summary
WD repeat domain 62 (Wdr62) encodes a protein involved in mitosis regulation. [Date last reviewed: 2019-09-19] (FlyBase Gene Snapshot)
All Summaries
Key Links
Genomic Location
Cytogenetic map
22B4-22B6
Sequence location
Recombination map
2-3
RefSeq locus
NT_033779 REGION:1884622..1944289
Sequence
Get Decorated FASTA
Genomic Maps
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
NCBI
UCSC
Ensembl
PopFly
Function
Gene Ontology (GO) Annotations (5 terms)
Molecular Function (0 terms)
Terms Based on Experimental Evidence (0 terms)
Terms Based on Predictions or Assertions (0 terms)
Biological Process (2 terms)
Terms Based on Experimental Evidence (1 term)
CV Term
Evidence
References
involved_in regulation of mitotic cell cycle
inferred from mutant phenotype
(Ramdas Nair et al., 2016)
Terms Based on Predictions or Assertions (2 terms)
CV Term
Evidence
References
involved_in mitotic spindle organization
inferred from sequence or structural similarity with UniProtKB:O43379
(Gene Ontology Curators, 2002-)
involved_in regulation of mitotic cell cycle
inferred from biological aspect of ancestor with PANTHER:PTN000522006
(GO Reference Genome Project, 2011-)
Cellular Component (3 terms)
Terms Based on Experimental Evidence (2 terms)
CV Term
Evidence
References
located_in interphase microtubule organizing center
inferred from direct assay
(Ramdas Nair et al., 2016)
located_in mitotic spindle
inferred from direct assay
(Ramdas Nair et al., 2016)
Terms Based on Predictions or Assertions (2 terms)
CV Term
Evidence
References
is_active_in mitotic spindle
inferred from biological aspect of ancestor with PANTHER:PTN000522006
(GO Reference Genome Project, 2011-)
located_in spindle pole
inferred from sequence or structural similarity with UniProtKB:O43379
(Gene Ontology Curators, 2002-)
Gene Group (FlyBase)
Protein Family (UniProt)
-
Protein Signatures (InterPro)
Summaries
Gene Snapshot
WD repeat domain 62 (Wdr62) encodes a protein involved in mitosis regulation. [Date last reviewed: 2019-09-19]
Summary (Interactive Fly)

controls brain growth through lineage-specific interactions with master mitotic signaling kinase Aurora A - glial lineage-specific WDR62 depletion significantly decreases brain volume - JNK interacts with Wdr62 at the spindle and transcriptionally represses the kinesin Kif1a to promote planar spindle orientation - required to maintain centrosome asymmetry in Drosophila neuroblasts by directly or indirectly stabilizing the interphase MTs necessary to accumulate and maintain pericentriolar matrix-associated Polo - control of intestinal cell fate

Gene Model and Products
Number of Transcripts
8
Number of Unique Polypeptides
7

Please see the JBrowse view of Dmel\Wdr62 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)
Isoform displayed:
Pfam protein domains
InterPro name
classification
start
end
Protein Domains (via SMART)
Isoform displayed:
SMART protein domains
InterPro name
classification
start
end
Structure
Protein 3D structure   (Predicted by AlphaFold)   (AlphaFold entry M9PB01)

If you don't see a structure in the viewer, refresh your browser.
Model Confidence:
  • Very high (pLDDT > 90)
  • Confident (90 > pLDDT > 70)
  • Low (70 > pLDDT > 50)
  • Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Experimentally Determined Structures
Crossreferences
Comments on Gene Model

Gene model reviewed during 5.41

Annotated transcripts do not represent all possible combinations of alternative exons and/or alternative promoters.

Low-frequency RNA-Seq exon junction(s) not annotated.

Annotated transcripts do not represent all supported alternative splices within 5' UTR.

Gene model reviewed during 5.46

Tissue-specific extension of 3' UTRs observed during later stages (FBrf0218523, FBrf0219848); all variants may not be annotated

Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Assoc. CDS (aa)
Wdr62-RA
FBtr0077811
NM_134786
6406
1508
Wdr62-RB
FBtr0110882
NM_001042863
6246
1504
Wdr62-RC
FBtr0110883
NM_001042862
8783
2347
Wdr62-RD
FBtr0113011
NM_001103580
6721
1539
Wdr62-RE
FBtr0113012
NM_001103581
6049
1508
Wdr62-RF
FBtr0309828
NM_001258915
5930
1554
Wdr62-RG
FBtr0333006
NM_001272957
8459
2397
Wdr62-RH
FBtr0333007
NM_001272958
5953
1476
Additional Transcript Data and Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
UniProt
RefSeq ID
GenBank
Wdr62-PA
FBpp0077488
163.9
1508
8.05
Q9VQ54
NP_608630
AAF51327
Wdr62-PB
FBpp0110182
163.2
1504
7.87
Q0E8U6
NP_001036328
ABI31283
Wdr62-PC
FBpp0110183
257.6
2347
8.07
Q0E8U7
NP_001036327
ABI31282
Wdr62-PD
FBpp0111924
166.9
1539
8.05
A8DYT1
NP_001097050
ABV53599
Wdr62-PE
FBpp0111925
163.9
1508
8.05
Q9VQ54
NP_001097051
ABV53600
Wdr62-PF
FBpp0301564
168.5
1554
8.16
M9NE65
NP_001245844
AFH03521
Wdr62-PG
FBpp0305221
262.8
2397
8.26
M9PB01
NP_001259886
AGB92423
Wdr62-PH
FBpp0305222
160.4
1476
8.00
M9PBP2
NP_001259887
AGB92424
Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

1508 aa isoforms: Wdr62-PA, Wdr62-PE
Additional Polypeptide Data and Comments
Reported size (kDa)
Comments
External Data
Crossreferences
InterPro - A database of protein families, domains and functional sites
Linkouts
Sequences Consistent with the Gene Model
Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Wdr62 using the Feature Mapper tool.

External Data
Crossreferences
Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
Linkouts
Expression Data
Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

-0.81

Transcript Expression
Polypeptide Expression
mass spectroscopy
Stage
Tissue/Position (including subcellular localization)
Reference
adult stage
adult head
(Aradska et al., 2015)
day 5 of adulthood | male -- day 7 of adulthood | male
spermatozoon
(Wasbrough et al., 2010)
Additional Descriptive Data
Marker for
 
Subcellular Localization
CV Term
Evidence
References
located_in interphase microtubule organizing center
inferred from direct assay
(Ramdas Nair et al., 2016)
located_in mitotic spindle
inferred from direct assay
(Ramdas Nair et al., 2016)
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\Wdr62 in JBrowse
RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region
Bulk Downloads
RNA-Seq RPKM values for all genes
Reference
See Gelbart and Emmert, 2013 for analysis details and data files for all genes.
Developmental Proteome: Life Cycle
Developmental Proteome: Embryogenesis
External Data and Images
Linkouts
BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species
EMBL-EBI Single Cell Expression Atlas - Single cell expression across species
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data
Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
Flygut - An atlas of the Drosophila adult midgut
Images
FlyExpress - Embryonic expression images (BDGP data)
  • Stages(s) 1-3
  • Stages(s) 4-6
  • Stages(s) 9-10
  • Stages(s) 11-12
  • Stages(s) 13-16
FlyBase Wiki
Image Based Resources
Alleles, Insertions, Transgenic Constructs, and Aberrations
Classical and Insertion Alleles ( 27 )
For All Classical and Insertion Alleles Show
 
Other relevant insertions
Transgenic Constructs ( 9 )
For All Alleles Carried on Transgenic Constructs Show
Transgenic constructs containing/affecting coding region of Wdr62
Transgenic constructs containing regulatory region of Wdr62
Aberrations (Deficiencies and Duplications) ( 1 )
Variants
Variant Molecular Consequences
Alleles Representing Disease-Implicated Variants
Phenotypes
For more details about a specific phenotype click on the relevant allele symbol.
Lethality
Allele
partially lethal, with Dcr-2UAS.cDa, Scer\GAL4elav.PLu
partially lethal - majority die (with Df(2L)Exel8005)
partially lethal - majority live (with Df(2L)Exel8005)
viable, with Scer\GAL4Mef2.PR
viable, with Scer\GAL4pnr-MD237
viable, with Scer\GAL4tin.CΔ4
Other Phenotypes
Allele
abnormal developmental rate (with Df(2L)Exel8005)
abnormal mitotic cell cycle | third instar larval stage, with Scer\GAL4repo.PU
abnormal mitotic cell cycle | third instar larval stage, with Scer\GAL4repo
abnormal mitotic cell cycle | third instar larval stage, with Scer\GAL4wor.PU
abnormal mitotic cell cycle | third instar larval stage (with Df(2L)Exel8005)
abnormal neuroanatomy | third instar larval stage, with Scer\GAL4insc-Mz1407
abnormal neuroanatomy | third instar larval stage, with Scer\GAL4repo
abnormal neuroanatomy | third instar larval stage, with Scer\GAL4wor.PA
abnormal size | third instar larval stage, with Scer\GAL4repo
decreased cell number | third instar larval stage, with Scer\GAL4insc-Mz1407
decreased cell number | third instar larval stage, with Scer\GAL4repo
decreased cell number | third instar larval stage (with Df(2L)Exel8005)
hypoplasia | third instar larval stage (with Df(2L)Exel8005)
increased cell death | third instar larval stage, with Scer\GAL4repo
increased cell number | third instar larval stage, with Scer\GAL4insc.PU
increased cell number | third instar larval stage, with Scer\GAL4repo.PU
increased cell size | third instar larval stage, with Scer\GAL4repo.PU
increased occurrence of cell division | third instar larval stage, with Scer\GAL4insc-Mz1407
increased occurrence of cell division | third instar larval stage, with Scer\GAL4repo.PU
increased occurrence of cell division | third instar larval stage, with Scer\GAL4repo
increased size | third instar larval stage, with Scer\GAL4insc.PU
increased size | third instar larval stage, with Scer\GAL4repo.PU
majority die during P-stage (with Df(2L)Exel8005)
some die during P-stage (with Df(2L)Exel8005)
some die during pupal stage, with Dcr-2UAS.cDa, Scer\GAL4elav.PLu
Phenotype manifest in
Allele
centrosome | third instar larval stage (with Df(2L)Exel8005)
larval brain | third instar larval stage, with Scer\GAL4insc.PU
larval brain | third instar larval stage, with Scer\GAL4repo.PU
larval brain | third instar larval stage, with Scer\GAL4repo
larval brain | third instar larval stage (with Df(2L)Exel8005)
larval glial cell | increased number | third instar larval stage, with Scer\GAL4repo.PU
larval glial cell | third instar larval stage, with Scer\GAL4repo
larval neuroblast | increased number | third instar larval stage, with Scer\GAL4insc.PU
larval neuroblast | increased number | third instar larval stage, with Scer\GAL4repo.PU
larval neuroblast | third instar larval stage, with Scer\GAL4insc-Mz1407
larval neuroblast | third instar larval stage, with Scer\GAL4repo
larval neuroblast | third instar larval stage, with Scer\GAL4wor.PA
microtubule | third instar larval stage, with Scer\GAL4wor.PU
microtubule | third instar larval stage (with Df(2L)Exel8005)
microtubule organizing center | third instar larval stage (with Df(2L)Exel8005)
mitotic spindle | third instar larval stage, with Scer\GAL4wor.PA
mitotic spindle | third instar larval stage (with Df(2L)Exel8005)
neuroblast | third instar larval stage, with Scer\GAL4wor.PU
neuroblast | third instar larval stage (with Df(2L)Exel8005)
nucleolus | third instar larval stage, with Scer\GAL4repo.PU
Orthologs
Downloads
Download All DIOPT Orthologs
Human Orthologs (via DIOPT v9.1)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
Domainoid
eggNOG
Hieranoid
Homologene
Inparanoid
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
SonicParanoid
Alignment
Complementation?
Transgene?
Homo sapiens (Human) (21)
Hsap\MAPKBP1
9 of 14
Yes
Yes
Hsap\WDR62
8 of 14
No
Yes
Hsap\APAF1
1 of 14
No
No
Hsap\CFAP57
1 of 14
No
No
Hsap\DCAF4
1 of 14
No
Yes
Hsap\DCAF4L1
1 of 14
No
Yes
Hsap\DCAF4L2
1 of 14
No
Yes
Hsap\EML3
1 of 14
No
No
Hsap\EML5
1 of 14
No
No
Hsap\EML6
1 of 14
No
Yes
Hsap\NEDD1
1 of 14
No
No
Hsap\NWD1
1 of 14
No
No
Hsap\POC1B
1 of 14
No
No
1  
Hsap\TBL3
1 of 14
No
No
Hsap\TEP1
1 of 14
No
No
Hsap\WDR17
1 of 14
No
No
Hsap\WDR27
1 of 14
No
No
Hsap\WDR38
1 of 14
No
No
Hsap\WDR43
1 of 14
No
No
Hsap\WDR88
1 of 14
No
No
Hsap\WDR90
1 of 14
No
No
Model Organism Orthologs (via DIOPT v9.1)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
Domainoid
eggNOG
Hieranoid
Homologene
Inparanoid
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
SonicParanoid
Alignment
Complementation?
Transgene?
Rattus norvegicus (Norway rat) (19)
Rnor\Wdr62
9 of 14
Yes
Yes
Rnor\Mapkbp1
8 of 14
No
Yes
Rnor\Apaf1
1 of 14
No
No
Rnor\Cfap44
1 of 14
No
No
Rnor\Dcaf4
1 of 14
No
Yes
Rnor\Eml3
1 of 14
No
No
Rnor\Eml4
1 of 14
No
No
Rnor\Eml5
1 of 14
No
No
Rnor\Eml6
1 of 14
No
No
Rnor\Nedd1
1 of 14
No
No
Rnor\Poc1b
1 of 14
No
No
Rnor\Tbl3
1 of 14
No
No
Rnor\Tep1
1 of 14
No
Yes
Rnor\Wdr17
1 of 14
No
No
Rnor\Wdr27
1 of 14
No
No
Rnor\Wdr38
1 of 14
No
No
Rnor\Wdr43
1 of 14
No
No
Rnor\Wdr90
1 of 14
No
Yes
Rnor\Wdr97
1 of 14
No
Yes
Mus musculus (laboratory mouse) (20)
Mmus\Wdr62
9 of 14
Yes
Yes
Mmus\Mapkbp1
7 of 14
No
Yes
Mmus\Apaf1
1 of 14
No
No
Mmus\Cfap44
1 of 14
No
No
Mmus\Cfap57
1 of 14
No
No
Mmus\Dcaf4
1 of 14
No
Yes
Mmus\Eml2
1 of 14
No
No
Mmus\Eml3
1 of 14
No
No
Mmus\Eml5
1 of 14
No
Yes
Mmus\Eml6
1 of 14
No
No
Mmus\Gm35339
1 of 14
No
Yes
Mmus\Nwd1
1 of 14
No
No
Mmus\Poc1b
1 of 14
No
No
Mmus\Tbl3
1 of 14
No
No
Mmus\Wdr17
1 of 14
No
Yes
Mmus\Wdr27
1 of 14
No
Yes
Mmus\Wdr38
1 of 14
No
No
Mmus\Wdr43
1 of 14
No
No
Mmus\Wdr88
1 of 14
No
Yes
Mmus\Wdr90
1 of 14
No
No
Xenopus tropicalis (Western clawed frog) (9)
Xtro\wdr62
6 of 13
Yes
Yes
Xtro\mapkbp1
5 of 13
No
Yes
Xtro\eml1
1 of 13
No
No
Xtro\eml4
1 of 13
No
No
Xtro\eml5
1 of 13
No
Yes
Xtro\eml6
1 of 13
No
Yes
Xtro\kcnn1
1 of 13
No
No
Xtro\rnf145
1 of 13
No
No
Xtro\wdr90
1 of 13
No
Yes
Danio rerio (Zebrafish) (18)
Drer\wdr62
8 of 14
Yes
Yes
Drer\mapkbp1
7 of 14
No
Yes
Drer\cfap52
1 of 14
No
No
Drer\cfap57
1 of 14
No
No
Drer\eml1
1 of 14
No
No
Drer\eml4
1 of 14
No
No
Drer\eml5
1 of 14
No
No
Drer\eml6
1 of 14
No
Yes
Drer\LOC110437968
1 of 14
No
Yes
Drer\nedd1
1 of 14
No
No
Drer\nwd1
1 of 14
No
No
Drer\poc1b
1 of 14
No
No
Drer\si:ch73-174h16.5
1 of 14
No
Yes
Drer\wdr17
1 of 14
No
No
Drer\wdr21
1 of 14
No
Yes
Drer\wdr27
1 of 14
No
Yes
Drer\wdr43
1 of 14
No
No
Drer\wdr90
1 of 14
No
No
Caenorhabditis elegans (Nematode, roundworm) (3)
Cele\wdr-62
8 of 14
Yes
Yes
Cele\wdr-5.1
1 of 14
No
No
Cele\wdr-5.3
1 of 14
No
No
Anopheles gambiae (African malaria mosquito) (4)
Agam\AgaP_AGAP009285
10 of 12
Yes
Yes
Agam\AgaP_AGAP005915
1 of 12
No
No
Agam\AgaP_AGAP009615
1 of 12
No
No
Agam\AgaP_AGAP012350
1 of 12
No
No
Arabidopsis thaliana (thale-cress) (1)
Atha\AT3G09080
9 of 13
Yes
Yes
Saccharomyces cerevisiae (Brewer's yeast) (4)
Scer\MAK11
1 of 13
Yes
No
Scer\PWP2
1 of 13
Yes
No
Scer\RSA4
1 of 13
Yes
No
Scer\TUP1
1 of 13
Yes
No
Schizosaccharomyces pombe (Fission yeast) (2)
Spom\SPCC18.05c
1 of 12
Yes
No
Spom\utp13
1 of 12
Yes
No
Escherichia coli (enterobacterium) (0)
Other Organism Orthologs (via OrthoDB)
Data provided directly from OrthoDB:Wdr62. Refer to their site for version information.
Paralogs
Downloads
Download All DIOPT Paralogs
Paralogs (via DIOPT v9.1)
Gene Symbol
Score
Source
Compara
Domainoid
eggNOG
Homologene
Inparanoid
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
SonicParanoid
Alignment
Drosophila melanogaster (Fruit fly) (10)
CG3436
1 of 13
CG7568
1 of 13
CG10064
1 of 13
CG10931
1 of 13
CG12608
1 of 13
Lis-1
1 of 13
Poc1
1 of 13
Rbcn-3B
1 of 13
Wdr81
1 of 13
wds
1 of 13
Human Disease Associations
FlyBase Human Disease Model Reports
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 5 )
Potential Models Based on Orthology ( 2 )
Modifiers Based on Experimental Evidence ( 3 )
Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)
Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
Homo sapiens (Human)
Gene name
Score
OMIM
OMIM Phenotype
DO term
Complementation?
Transgene?
MAPKBP1; mitogen-activated protein kinase binding protein 1
9 of 14
616786
WDR62; WD repeat domain 62
8 of 14
613583
Functional Complementation Data
Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
Interactions
Summary of Physical Interactions
Interaction Browsers
Summary of Genetic Interactions
Interaction Browsers
View in FlyBase Interactions Browser   View in MIST tool (external link)
Please look at the allele data for full details of the genetic interactions
Starting gene(s)
Interaction type
Interacting gene(s)
Reference
Wdr62
suppressible
aurA
(Shohayeb et al., 2020)
Wdr62
enhanceable
aurA
(Lim et al., 2017)
Starting gene(s)
Interaction type
Interacting gene(s)
Reference
Akt
suppressible
Wdr62
(Shohayeb et al., 2020)
asp
enhanceable
Wdr62
(Schoborg et al., 2019)
aurA
suppressible
Wdr62
(Shohayeb et al., 2020, Lim et al., 2017)
aurA
enhanceable
Wdr62
(Lim et al., 2017)
Pi3K92E
suppressible
Wdr62
(Shohayeb et al., 2020)
External Data
Linkouts
DroID - A comprehensive database of gene and protein interactions.
Pathways
Signaling Pathways (FlyBase)
Metabolic Pathways
FlyBase
External Links
External Data
Linkouts
SignaLink - A signaling pathway resource with multi-layered regulatory networks.
Class of Gene
Genomic Location and Detailed Mapping Data
Chromosome (arm)
2L
Recombination map
2-3
Cytogenetic map
22B4-22B6
Sequence location
FlyBase Computed Cytological Location
Cytogenetic map
Evidence for location
22B4-22B6
Limits computationally determined from genome sequence between P{lacW}CG17646k11021 and P{EP}EP366
Experimentally Determined Cytological Location
Cytogenetic map
Notes
References
Experimentally Determined Recombination Data
Location

2-3

(FlyBase, 2016)

2-3.5

(Comeron et al., 2012)
Left of (cM)
Right of (cM)
Notes
Stocks and Reagents
Stocks (21)
Genomic Clones (46)
cDNA Clones (60)
 

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced
BDGP DGC clones
Other clones
Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones
Other clones
RNAi and Array Information
Linkouts
DRSC - Results frm RNAi screens
Antibody Information
Laboratory Generated Antibodies
 

monoclonal

(Ramdas Nair et al., 2016)
Commercially Available Antibodies
 
Cell Line Information
Publicly Available Cell Lines
 
    Other Stable Cell Lines
     
      Other Comments

      Wdr62 is required to maintain centrosome asymmetry during interphase in neuroblasts; it is required to maintain polo protein on the apical interphase microtubule organising center (MTOC). It also has a separate role in regulating cell cycle progression.

      (Ramdas Nair et al., 2016)
      Relationship to Other Genes
      Source for database merge of
      Additional comments
      Nomenclature History
      Source for database identify of

      Source for identity of: Wdr62 CG7337

      (Ramdas Nair et al., 2016)
      Nomenclature comments
      Etymology

      Gene is named "Wdr62" based on orthology with the human WDR62 gene.

      (Ramdas Nair et al., 2016)
      Synonyms and Secondary IDs (6)
      Datasets (0)
      Study focus (0)
      Experimental Role
      Project
      Project Type
      Title
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      External Crossreferences and Linkouts ( 82 )
      Sequence Crossreferences
      NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
      GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
      GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
      RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.
      UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.
      UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information
      Other crossreferences
      AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.
      BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
      DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species
      EMBL-EBI Single Cell Expression Atlas - Single cell expression across species
      FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data
      FlyMine - An integrated database for Drosophila genomics
      InterPro - A database of protein families, domains and functional sites
      KEGG Genes - Molecular building blocks of life in the genomic space.
      MARRVEL_MODEL - MARRVEL (model organism gene)
      Linkouts
      Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones
      DroID - A comprehensive database of gene and protein interactions.
      DRSC - Results frm RNAi screens
      Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
      FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
      FlyCyc Genes - Genes from a BioCyc PGDB for Dmel
      Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
      Flygut - An atlas of the Drosophila adult midgut
      iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)
      Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution
      SignaLink - A signaling pathway resource with multi-layered regulatory networks.
      References (70)