Gene model reviewed during 5.49
Annotated transcripts do not represent all possible combinations of alternative exons and/or alternative promoters.
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.56
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\uif using the Feature Mapper tool.
uif protein is first detected in stage 7 embryos in the cephalic furrow and ventral furrow. In late stage embryos, is persists in ectodermal tissues and is very strong in the tracheal system. It is also detected in the epidermis, foregut, hindgut, and salivary gland. In larvae, it is found at high levels in the epidermis, foregut, and hindgut. It is present at high levels in imaginal discs and at lower levels in the epidermis.
GBrowse - Visual display of RNA-Seq signalsView Dmel\uif in GBrowse 2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Identified as a candidate gene for hypoxia-specific selection (via an experimental evolution paradigm) that is also differentially expressed between control and hypoxia-adapted larvae.
The gene is named "uninflatable" based upon the defective tracheal inflation phenotype of mutants.