Gene model reviewed during 5.49
There is only one protein coding transcript and one polypeptide associated with this gene
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Rad51D using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\Rad51D in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
FlyBase curator comment: For clarity and consistency with the vertebrate nomenclature, the gene previously called 'Rad51C' (CG2412/FBgn0033389) was renamed 'Rad51D', and the gene previously called 'Rad51D' (CG6318,FBgn0030931) was renamed 'Xrcc2'. (These changes occurred in the FB2016_04 release.)
The "rad201" chromosome contains a number of lesions in two different genes. These are: F50L in the CG42382 annotation, and K61E, V93A and Y108H in the CG2412 annotation (corresponding to the Rad51C gene). In addition, an opus element is inserted in the Rad51C promoter region approximately 400bp upstream of the start codon. This mutant allele was isolated from a natural population, and thus it is not known which of the lesions are neutral and which cause the mutant phenotype.
The "rad201" complementation group has been associated with the "CG8016" annotation on FlyBase. However, evidence suggests that "rad201" instead corresponds to the neighbouring annotation, CG2412; the "rad2011" allele has a lesion within the CG2412 open reading frame (although no lesion has been found in the "rad201ZII-0670" allele), and the protein encoded by CG2412 interacts with Spf45 protein.
Source for identity of Rad51C CG2412 was sequence comparison ( date:000815 ).
Named 'Rad51D' after the vertebrate ortholog.