FB2020_06, released Dec 22, 2020

Gene: Dmel\Atg9

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General Information
Symbol
Dmel\Atg9
Species
D. melanogaster
Name
Autophagy-related 9
Annotation Symbol
CG3615
Feature Type
protein_coding_gene
FlyBase ID
FBgn0034110
Gene Model Status
Current
Stock Availability
5 publicly available
Gene Snapshot
Autophagy-related 9 (Atg9) encodes an integral membrane protein acting as a membrane carrier for forming autophagosomes. It regulates TOR and JNK signaling pathways via autophagy. [Date last reviewed: 2019-07-11]
Other Summaries
Key Links
Genomic Location
Cytogenetic map
53B1-53B2
Sequence location
2R:16,294,400..16,297,232 [+]
Recombination map

2-79

RefSeq locus
NT_033778 REGION:16294400..16297232
Sequence
Get Decorated FASTA
Genomic Maps
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
NCBI
UCSC
Ensembl
PopFly
Function
GO Summary Ribbons
Gene Ontology (GO) Annotations (18 terms)
Molecular Function (0 terms)
There is no information supporting a Molecular Function term for this gene. (Based on a review of available data on: 2012-05-10 )
Terms Based on Experimental Evidence (0 terms)
Terms Based on Predictions or Assertions (0 terms)
Biological Process (13 terms)
Terms Based on Experimental Evidence (9 terms)
CV Term
Evidence
References
involved_in autophagy
inferred from mutant phenotype
(Wen et al., 2017, Xu et al., 2015, Lőw et al., 2013, Tang et al., 2013)
involved_in cellular response to oxidative stress
inferred from mutant phenotype
(Tang et al., 2013)
involved_in cellular response to starvation
inferred from mutant phenotype
(Tang et al., 2013, Zirin et al., 2013)
involved_in glycophagy
inferred from mutant phenotype
(Zirin et al., 2013)
involved_in intestinal epithelial structure maintenance
inferred from mutant phenotype
(Wen et al., 2017)
involved_in larval midgut cell programmed cell death
inferred from mutant phenotype
(Xu et al., 2015)
involved_in larval midgut histolysis
inferred from mutant phenotype
(Wen et al., 2017)
involved_in negative regulation of TOR signaling
inferred from mutant phenotype
(Wen et al., 2017)
involved_in positive regulation of JNK cascade
inferred from mutant phenotype
(Tang et al., 2013)
inferred from genetic interaction with FLYBASE:bsk; FB:FBgn0000229
(Tang et al., 2013)
inferred from genetic interaction with FLYBASE:puc; FB:FBgn0243512
(Tang et al., 2013)
Terms Based on Predictions or Assertions (4 terms)
CV Term
Evidence
References
involved_in autophagosome assembly
inferred from sequence or structural similarity with SGD:S000002308
(FlyBase Curators, 2008--)
involved_in autophagy of mitochondrion
inferred from biological aspect of ancestor with PANTHER:PTN000315580
(assigned by GO_Central )
(Gaudet et al., 2011)
involved_in late nucleophagy
inferred from biological aspect of ancestor with PANTHER:PTN000315580
(assigned by GO_Central )
(Gaudet et al., 2011)
involved_in protein localization to phagophore assembly site
inferred from biological aspect of ancestor with PANTHER:PTN000315580
(assigned by GO_Central )
(Gaudet et al., 2011)
Cellular Component (5 terms)
Terms Based on Experimental Evidence (2 terms)
CV Term
Evidence
References
located_in cell junction
inferred from direct assay
(Tang et al., 2013)
located_in cytoplasm
inferred from direct assay
(Tang et al., 2013)
Terms Based on Predictions or Assertions (3 terms)
CV Term
Evidence
References
located_in autophagosome
inferred from biological aspect of ancestor with PANTHER:PTN000315580
(assigned by GO_Central )
(Gaudet et al., 2011)
located_in integral component of membrane
inferred from sequence model
(FlyBase Curators, 2011-)
located_in phagophore assembly site
inferred from biological aspect of ancestor with PANTHER:PTN000315580
(assigned by GO_Central )
(Gaudet et al., 2011)
Gene Group (FlyBase)
Protein Family (UniProt)
-
Protein Signatures (InterPro)
Summaries
Gene Group (FlyBase)
AUTOPHAGY-RELATED GENES -
The Autophagy-related genes (Atg), characterized extensively in yeast, are a set of approximately twenty evolutionarily conserved genes required for autophagy. Autophagy (specifically, macroautophagy) is the process of bulk degradation of cytoplasmic material. It takes place by the assembly of a double membrane vesicle, the autophagosome, which delivers cargo to the lysosome for recycling. (Adapted from FBrf0219844 and FBrf020902).
Summary (Interactive Fly)
Gene Model and Products
Number of Transcripts
2
Number of Unique Polypeptides
2

Please see the JBrowse view of Dmel\Atg9 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)
Isoform displayed:
Pfam protein domains
InterPro name
classification
start
end
Protein Domains (via SMART)
Isoform displayed:
SMART protein domains
InterPro name
classification
start
end
Comments on Gene Model

Stop-codon suppression (UAG) postulated; FBrf0216884

gene_with_stop_codon_read_through ; SO:0000697

Gene model reviewed during 5.44

Gene model reviewed during 5.50

Sequence Ontology: Class of Gene
gene_with_stop_codon_read_through
(Jungreis et al., 2011)
nuclear_gene
protein_coding_gene
Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Assoc. CDS (aa)
Atg9-RA
FBtr0087141
NM_137270
2833
845
Atg9-RB
FBtr0329958
NM_001274094
2833
852
Additional Transcript Data and Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
RefSeq ID
GenBank
Atg9-PA
FBpp0086285
95.4
845
6.66
NP_611114
AAF58018
Atg9-PB
FBpp0302990
96.3
852
6.65
NP_001261023
AGB93555
Polypeptides with Identical Sequences

None of the polypeptides share 100% sequence identity.

Additional Polypeptide Data and Comments
Reported size (kDa)
Comments
External Data
Crossreferences
InterPro - A database of protein families, domains and functional sites
Linkouts
Sequences Consistent with the Gene Model
Nucleotide / Polypeptide Records
 
UniProt
Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Atg9 using the Feature Mapper tool.

External Data
Crossreferences
Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
Linkouts
Expression Data
Expression Summary Ribbons
Colored tiles in ribbon indicate that expression data has been curated by FlyBase for that anatomical location. Colorless tiles indicate that there is no curated data for that location.
For complete stage-specific expression data, view the modENCODE Development RNA-Seq section under High-Throughput Expression below.
Transcript Expression
in situ
Stage
Tissue/Position (including subcellular localization)
Reference
embryonic stage 1 -- 3
organism

Comment: maternally deposited

(Fisher et al., 2012)
embryonic stage 4 -- 6
organism | ubiquitous
(Fisher et al., 2012)
embryonic stage 7 -- 8
antennal anlage

Comment: reported as procephalic ectoderm anlage

(Fisher et al., 2012)
central brain anlage

Comment: reported as procephalic ectoderm anlage

(Fisher et al., 2012)
dorsal head epidermis anlage

Comment: reported as procephalic ectoderm anlage

(Fisher et al., 2012)
visual anlage

Comment: reported as procephalic ectoderm anlage

(Fisher et al., 2012)
organism | ubiquitous
(Fisher et al., 2012)
embryonic stage 9 -- 10
organism | faint | ubiquitous
(Fisher et al., 2012)
embryonic stage 11 -- 12
organism | faint | ubiquitous
(Fisher et al., 2012)
northern blot
Stage
Tissue/Position (including subcellular localization)
Reference
pupal stage
salivary gland
(Lee et al., 2003)
Additional Descriptive Data

The expression of this gene along with several others is induced in salivary glands in pupae at the time of head eversion. This stage is characterized by an increase in the ecdysone titer as well as large amounts of cell death in this tissue.

(Lee et al., 2003)
Marker for
 
Subcellular Localization
CV Term
Polypeptide Expression
mass spectroscopy
Stage
Tissue/Position (including subcellular localization)
Reference
adult stage
adult head
(Aradska et al., 2015)
Additional Descriptive Data
Marker for
 
Subcellular Localization
CV Term
Evidence
References
located_in cell junction
inferred from direct assay
(Tang et al., 2013)
located_in cytoplasm
inferred from direct assay
(Tang et al., 2013)
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools

GBrowse - Visual display of RNA-Seq signals

View Dmel\Atg9 in GBrowse 2
RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region
Bulk Downloads
RNA-Seq RPKM values for all genes
Reference
See Gelbart and Emmert, 2013 for analysis details and data files for all genes.
Developmental Proteome: Life Cycle
Developmental Proteome: Embryogenesis
External Data and Images
Linkouts
BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
FLIGHT - Cell culture data for RNAi and other high-throughput technologies
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
Flygut - An atlas of the Drosophila adult midgut
Images
FlyExpress - Embryonic expression images (BDGP data)
  • Stages(s) 1-3
  • Stages(s) 4-6
  • Stages(s) 7-8
  • Stages(s) 9-10
  • Stages(s) 11-12
FlyBase Wiki
Image Based Resources
Alleles, Insertions, and Transgenic Constructs
Classical and Insertion Alleles ( 4 )
For All Classical and Insertion Alleles Show
 
Other relevant insertions
Transgenic Constructs ( 14 )
For All Alleles Carried on Transgenic Constructs Show
Transgenic constructs containing/affecting coding region of Atg9
Transgenic constructs containing regulatory region of Atg9
Deletions and Duplications ( 2 )
Phenotypes
For more details about a specific phenotype click on the relevant allele symbol.
Lethality
Allele
lethal
lethal (with Atg9d51)
lethal (with Atg9Gal4KO)
lethal | recessive
viable, with Dcr-2UAS.cDa, Scer\GAL4elav.PLu
viable, with Scer\GAL4Mef2.PR
viable, with Scer\GAL4pnr-MD237
viable, with Scer\GAL4tin.CΔ4
Sterility
Allele
sterile
sterile (with Atg9d51)
sterile (with Atg9Gal4KO)
Other Phenotypes
Allele
cell shape defective, with Scer\GAL4NP0001
cell shape defective | adult stage, with Scer\GAL4Tub.PU
cell shape defective | adult stage (with Atg9d51)
cell shape defective | adult stage (with Atg9Gal4KO)
decreased cell death | P-stage, with Scer\GAL4NP0001
increased cell death | third instar larval stage, with Scer\GAL4GMR.PU
increased cell size, with Scer\GAL4NP0001
increased cell size | adult stage, with Scer\GAL4Tub.PU
increased cell size | adult stage (with Atg9d51)
increased cell size | adult stage (with Atg9Gal4KO)
increased cell size | adult stage | somatic clone
increased occurrence of cell division | adult stage, with Scer\GAL4esg.PU
locomotor behavior defective | adult stage (with Atg9d51)
locomotor behavior defective | adult stage (with Atg9Gal4KO)
short lived, with Scer\GAL4Mef2.PU
short lived, with Scer\GAL4tin.CΔ4
short lived, with Scer\GAL4Tub.PU
short lived (with Atg9d51)
short lived (with Atg9Gal4KO)
size defective | adult stage (with Atg9d51)
size defective | adult stage (with Atg9Gal4KO)
size defective | larval stage (with Atg9d51)
size defective | larval stage (with Atg9Gal4KO)
size defective | P-stage, with Scer\GAL4NP0001
starvation stress response defective | larval stage, with Scer\GAL4Cg.PU
visible | adult stage, with Scer\GAL4ap-md544
visible | adult stage, with Scer\GAL4GMR.PU
Phenotype manifest in
Allele
adult fat body (with Atg9d51)
adult fat body (with Atg9Gal4KO)
adult fat body | nutrition conditional, with Scer\GAL4Tub.PU
adult heart muscle | progressive, with Scer\GAL4Mef2.PU
adult midgut (with Atg9d51)
adult midgut (with Atg9Gal4KO)
adult midgut epithelium, with Scer\GAL4esg.PU
adult midgut epithelium, with Scer\GAL4NP0001
adult midgut epithelium, with Scer\GAL4Tub.PU
adult midgut epithelium (with Atg9d51)
adult midgut epithelium (with Atg9Gal4KO)
autophagosome |  :chemical conditional | nutrition conditional, with Scer\GAL4Mef2.PR
autophagosome | adult stage | nutrition conditional, with Scer\GAL4Tub.PU
autophagosome | adult stage | nutrition conditional (with Atg9d51)
autophagosome | adult stage | nutrition conditional (with Atg9Gal4KO)
autophagosome | larval stage (with Atg9d51)
autophagosome | larval stage (with Atg9Gal4KO)
cytoplasmic vesicle | early third instar larval stage, with Scer\GAL4Cg.PA
embryonic/larval fat body | larval stage, with Scer\GAL4Cg.PU
embryonic/larval fat body | larval stage (with Atg9d51)
embryonic/larval fat body | larval stage (with Atg9Gal4KO)
embryonic/larval fat body | somatic clone | third instar larval stage, with Scer\GAL4Act5C.PP
embryonic/larval midgut | P-stage, with Scer\GAL4NP0001
enterocyte of posterior adult midgut epithelium | somatic clone
eye, with Scer\GAL4GMR.PU
eye disc | third instar larval stage, with Scer\GAL4GMR.PU
fat cell | early third instar larval stage | somatic clone, with Scer\GAL4Cg.PA
gastric caecum (with Atg9d51)
gastric caecum (with Atg9Gal4KO)
gastric caecum | P-stage, with Scer\GAL4NP0001
indirect flight muscle | day 40 of adulthood, with Scer\GAL4Mef2.PU
intestinal stem cell | chemical conditional, with Scer\GAL4NP0001
intestinal stem cell | chemical conditional, with Scer\GAL4NP5130
lysosome | adult stage | nutrition conditional, with Scer\GAL4Tub.PU
lysosome | adult stage | nutrition conditional (with Atg9d51)
lysosome | adult stage | nutrition conditional (with Atg9Gal4KO)
lysosome | larval stage (with Atg9d51)
lysosome | larval stage (with Atg9Gal4KO)
mitochondrion | adult stage, with Scer\GAL4Mef2.PU
skeletal muscle of thorax | adult stage (with Atg9d51)
skeletal muscle of thorax | adult stage (with Atg9Gal4KO)
visceral mesoderm | adult stage (with Atg9d51)
visceral mesoderm | adult stage (with Atg9Gal4KO)
wing, with Scer\GAL4ap-md544
Orthologs
Downloads
Download All DIOPT Orthologs
Download All OrthoDB Orthologs
Human Orthologs (via DIOPT v8.0)
Homo sapiens (Human) (4)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
eggNOG
Hieranoid
Homologene
Inparanoid
Isobase
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
RoundUp
TreeFam
ZFIN
Alignment
Complementation?
Transgene?
Hsap\ATG9A
12 of 15
Yes
Yes
Hsap\ATG9B
6 of 15
No
Yes
Hsap\ABCB6
2 of 15
No
No
Hsap\PLP1
1 of 15
No
No
Model Organism Orthologs (via DIOPT v8.0)
Mus musculus (laboratory mouse) (2)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
eggNOG
Hieranoid
Homologene
Inparanoid
Isobase
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
RoundUp
TreeFam
ZFIN
Alignment
Complementation?
Transgene?
Mmus\Atg9a
10 of 15
Yes
Yes
Mmus\Atg9b
10 of 15
Yes
Yes
Rattus norvegicus (Norway rat) (3)
Rnor\Atg9a
11 of 13
Yes
Yes
Rnor\Atg9b
10 of 13
No
Yes
Rnor\LOC102557368
1 of 13
No
Yes
Xenopus tropicalis (Western clawed frog) (2)
Xtro\atg9b
9 of 12
Yes
Yes
Xtro\atg9a
8 of 12
No
Yes
Danio rerio (Zebrafish) (2)
Drer\atg9a
12 of 15
Yes
Yes
Drer\atg9b
7 of 15
No
Yes
Caenorhabditis elegans (Nematode, roundworm) (1)
Cele\atg-9
13 of 15
Yes
Yes
Arabidopsis thaliana (thale-cress) (1)
Atha\APG9
8 of 9
Yes
Yes
Saccharomyces cerevisiae (Brewer's yeast) (1)
Scer\ATG9
11 of 15
Yes
Yes
Schizosaccharomyces pombe (Fission yeast) (1)
Spom\atg9
9 of 12
Yes
Yes
Ortholog(s) in Drosophila Species (via OrthoDB v9.1) ( EOG091902Z2 )
Organism
Common Name
Gene
AAA Syntenic Ortholog
Multiple Dmel Genes in this Orthologous Group
Drosophila suzukii
Spotted wing Drosophila
Dsuz\DS10_00003189
Drosophila simulans
Dsim\Atg9
Drosophila sechellia
Dsec\Atg9
Drosophila erecta
Dere\Atg9
Drosophila yakuba
Dyak\Atg9
Drosophila ananassae
Dana\Atg9
Drosophila pseudoobscura pseudoobscura
Dpse\Atg9
Drosophila persimilis
Dper\GL10727
Drosophila willistoni
Dwil\GK20903
Drosophila virilis
Dvir\GJ18883
Drosophila mojavensis
Dmoj\GI19856
Drosophila grimshawi
Dgri\GH19901
Orthologs in non-Drosophila Dipterans (via OrthoDB v9.1) ( EOG091501UT )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Musca domestica
House fly
Mdoa\17018349
Glossina morsitans
Tsetse fly
Gmor\GMOY009568
Lucilia cuprina
Australian sheep blowfly
Lcup\FF38_02719
Mayetiola destructor
Hessian fly
Mdes\Mdes002285
Aedes aegypti
Yellow fever mosquito
Aaeg\APG9
Anopheles darlingi
American malaria mosquito
Adar\ADAC010428
Culex quinquefasciatus
Southern house mosquito
Cqui\CPIJ012964
Orthologs in non-Dipteran Insects (via OrthoDB v9.1) ( EOG090W02WN )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Bombyx mori
Silkmoth
Bmor\BGIBMGA012307
Danaus plexippus
Monarch butterfly
Dple\DPOGS212572-PA
Heliconius melpomene
Postman butterfly
Hmel\HMEL008818
Apis florea
Little honeybee
Aflo\2998971332
Apis mellifera
Western honey bee
Amel\Atg9
Bombus impatiens
Common eastern bumble bee
Bimp\BIMP15435
Bombus terrestris
Buff-tailed bumblebee
Bter\15208287
Linepithema humile
Argentine ant
Lhum\LH22982
Megachile rotundata
Alfalfa leafcutting bee
Mrot\MROTU:00095a
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG037281
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG021819
Dendroctonus ponderosae
Mountain pine beetle
Dpod\YQE_08656
Tribolium castaneum
Red flour beetle
Tcas\TC013228
Pediculus humanus
Human body louse
Phum\PHUM577780
Rhodnius prolixus
Kissing bug
Rpro\RPRC003473
Cimex lectularius
Bed bug
Clec\CLEC011740
Cimex lectularius
Bed bug
Clec\CLEC011737
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI000660
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI067571
Zootermopsis nevadensis
Nevada dampwood termite
Znev\Znev_01174
Orthologs in non-Insect Arthropods (via OrthoDB v9.1) ( EOG090X04CB )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Strigamia maritima
European centipede
Smar\SMAR011766
Stegodyphus mimosarum
African social velvet spider
Smim\KFM71307.1
Stegodyphus mimosarum
African social velvet spider
Smim\KFM71308.1
Daphnia pulex
Water flea
Dpux\DAPPUDRAFT_41567
Orthologs in non-Arthropod Metazoa (via OrthoDB v9.1) ( EOG091G01WQ )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Strongylocentrotus purpuratus
Purple sea urchin
Spur\Sp-Atg9aL
Strongylocentrotus purpuratus
Purple sea urchin
Spur\SPU_018436gn
Strongylocentrotus purpuratus
Purple sea urchin
Spur\SPU_014942gn
Ciona intestinalis
Vase tunicate
Cint\atg9a
Gallus gallus
Domestic chicken
Ggal\ATG9A
Paralogs
Downloads
Download All DIOPT Paralogs
Paralogs (via DIOPT v8.0)
Drosophila melanogaster (Fruit fly) (0)
No records found.
Human Disease Associations
FlyBase Human Disease Model Reports
Disease Model Summary Ribbon
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Allele
Disease
Evidence
References
Potential Models Based on Orthology ( 0 )
Human Ortholog
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 1 )
Allele
Disease
Interaction
References
Atg9GD2029
ameliorates  myotonic dystrophy type 1
modeled by Zzzz\CTGi480.UAS.cGa
(Bargiela et al., 2015)
Disease Associations of Human Orthologs (via DIOPT v8.0 and OMIM)
Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
Homo sapiens (Human)
Gene name
Score
OMIM
OMIM Phenotype
DO term
Complementation?
Transgene?
ATG9A; autophagy related 9A
12 of 15
612204
      ATG9B; autophagy related 9B
      6 of 15
      612205
          Functional Complementation Data
          Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
          Interactions
          Summary of Physical Interactions
          Summary of Genetic Interactions
          esyN Network Diagram
          esyN Network Key:
          Suppression
          Enhancement
          View in Interactions Browser
          Please look at the allele data for full details of the genetic interactions
          Starting gene(s)
          Interaction type
          Interacting gene(s)
          Reference
          Atg9
          enhanceable
          Akt1
          (Wen et al., 2017)
          Atg9
          suppressible
          Akt1
          (Wen et al., 2017)
          Atg9
          suppressible
          Atg1
          (Wen et al., 2017)
          Atg9
          suppressible
          Atg7
          (Tang et al., 2013)
          Atg9
          suppressible
          bsk
          (Tang et al., 2013)
          Atg9
          suppressible
          InR
          (Wen et al., 2017)
          Atg9
          suppressible
          Patj
          (Wen et al., 2017)
          Atg9
          suppressible
          Pi3K92E
          (Wen et al., 2017)
          Atg9
          suppressible
          puc
          (Tang et al., 2013)
          Atg9
          suppressible
          S6k
          (Wen et al., 2017)
          Atg9
          suppressible
          Tor
          (Wen et al., 2017)
          Atg9
          suppressible
          Traf6
          (Tang et al., 2013)
          Atg9
          suppressible
          Tsc1|gig
          (Wen et al., 2017)
          Starting gene(s)
          Interaction type
          Interacting gene(s)
          Reference
          Atg1
          suppressible
          Atg9
          (Tang et al., 2018)
          Atg12
          suppressible
          Atg9
          (Tang et al., 2013)
          Dcp-1
          suppressible
          Atg9
          (Shinoda et al., 2019)
          Decay
          suppressible
          Atg9
          (Shinoda et al., 2019)
          dom
          enhanceable
          Atg9
          (Kwon et al., 2013)
          puc
          suppressible
          Atg9
          (Tang et al., 2013)
          Tom40
          suppressible
          Atg9
          (Liu et al., 2018)
          External Data
          Linkouts
          DroID - A comprehensive database of gene and protein interactions.
          InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.
          MIST (genetic) - An integrated Molecular Interaction Database
          MIST (protein-protein) - An integrated Molecular Interaction Database
          Pathways
          Signaling Pathways (FlyBase)
          Metabolic Pathways
          External Data
          Linkouts
          KEGG Pathways - Wiring diagrams of molecular interactions, reactions and relations.
          Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.
          Genomic Location and Detailed Mapping Data
          Chromosome (arm)
          2R
          Recombination map

          2-79

          Cytogenetic map
          53B1-53B2
          Sequence location
          2R:16,294,400..16,297,232 [+]
          FlyBase Computed Cytological Location
          Cytogenetic map
          Evidence for location
          53B1-53B2
          Limits computationally determined from genome sequence between P{lacW}Lis-1k11702&P{EP}CG8443EP969 and P{lacW}l(2)k07824k07824&P{lacW}vegk03402
          Experimentally Determined Cytological Location
          Cytogenetic map
          Notes
          References
          Experimentally Determined Recombination Data
          Location

          2-79

          (FlyBase, 2016)

          2-81.9

          (Comeron et al., 2012)
          Left of (cM)
          Right of (cM)
          Notes
          Stocks and Reagents
          Stocks (5)
          Genomic Clones (18)
           

          Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

          cDNA Clones (201)
           

          Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

          cDNA clones, fully sequenced
          BDGP DGC clones
          Other clones
          Drosophila Genomics Resource Center cDNA clones

          For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

          cDNA Clones, End Sequenced (ESTs)
          BDGP DGC clones
          Other clones
          RNAi and Array Information
          Linkouts
          DRSC - Results frm RNAi screens
          GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
          Antibody Information
          Laboratory Generated Antibodies
           

          polyclonal

          (Nagy et al., 2014, Tang et al., 2013)
          Commercially Available Antibodies
           
          Other Information
          Relationship to Other Genes
          Source for database identify of

          Source for identity of: Atg9 CG3615

          (Scott et al., 2004)
          Source for database merge of
          Additional comments
          Other Comments
          Origin and Etymology
          Discoverer
          Etymology
          Identification
          External Crossreferences and Linkouts ( 44 )
          Sequence Crossreferences
          NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
          GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
          GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
          RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.
          UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information
          Other crossreferences
          BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
          Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones
          Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
          Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
          Flygut - An atlas of the Drosophila adult midgut
          GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
          InterPro - A database of protein families, domains and functional sites
          KEGG Genes - Molecular building blocks of life in the genomic space.
          modMine - A data warehouse for the modENCODE project
          Linkouts
          DPiM - Drosophila Protein interaction map
          DroID - A comprehensive database of gene and protein interactions.
          DRSC - Results frm RNAi screens
          FLIGHT - Cell culture data for RNAi and other high-throughput technologies
          FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
          FlyCyc Genes - Genes from a BioCyc PGDB for Dmel
          FlyMine - An integrated database for Drosophila genomics
          Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution
          InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.
          KEGG Pathways - Wiring diagrams of molecular interactions, reactions and relations.
          MIST (genetic) - An integrated Molecular Interaction Database
          MIST (protein-protein) - An integrated Molecular Interaction Database
          Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.
          Synonyms and Secondary IDs (7)
          Reported As
          Symbol Synonym
          ATG9
          (Yang et al., 2020, Kourtis and Tavernarakis, 2009)
          Atg9
          (Allen et al., 2020, Barthez et al., 2020, Chittoor-Vinod et al., 2020, Jacomin et al., 2020, Kiss et al., 2020, Khezri and Rusten, 2019, Meltzer et al., 2019, Prasad et al., 2019, Texada et al., 2019, Xu et al., 2019, Yan et al., 2019, Zhang et al., 2019, Billes et al., 2018, Csizmadia et al., 2018, Kuo et al., 2018, Liu et al., 2018, O'Keefe and Denton, 2018, Richardson and Portela, 2018, Tang et al., 2018, Galluzzi et al., 2017, Kim et al., 2017, Kuleesha et al., 2017, Manent et al., 2017, Péan et al., 2017, Wen et al., 2017, Kuleesha et al., 2016, Soukup et al., 2016, Bargiela et al., 2015, Denton et al., 2015, Kim et al., 2015, Xu et al., 2015, Yadav et al., 2015, Zhang and Baehrecke, 2015, Zirin et al., 2015, Banreti et al., 2014, Mulakkal et al., 2014, Nagy et al., 2014, Denton et al., 2013, Kwon et al., 2013, Lőw et al., 2013, Nagy et al., 2013, Tang et al., 2013, Velentzas et al., 2013, Zirin et al., 2013, Érdi et al., 2012, Garcia et al., 2012, Japanese National Institute of Genetics, 2012.5.21, Pircs et al., 2012, Jungreis et al., 2011, Qin et al., 2011, Chang and Neufeld, 2010, Kadandale et al., 2010, Liu and Lehmann, 2008, Martin et al., 2007)
          CG3615
          (Meadows, 2017.1.11, Fukuoh et al., 2014, Érdi et al., 2012, Ni et al., 2011.7.19, Perkins et al., 2009, Dostert et al., 2005, Lee et al., 2003, Boutros et al., 2002)
          atg9
          (Kinser and Pincus, 2020, Bhukel et al., 2019, Shinoda et al., 2019, Singh and Chowdhuri, 2018, Zhang et al., 2016, Kwon et al., 2013, Chen et al., 2012, Shelly et al., 2009)
          dAtg9
          (Li et al., 2016)
          Name Synonyms
          Autophagy-related 9
          Autophagy-specific gene 9
          (Scott et al., 2004)
          Secondary FlyBase IDs
            Datasets (0)
            Study focus (0)
            Experimental Role
            Project
            Project Type
            Title
            References (117)