fumin, fmn, dDAT, DmDAT
Please see the JBrowse view of Dmel\DAT for information on other features
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AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Stop-codon suppression (UGA) postulated; FBrf0216884
Gene model reviewed during 5.44
Gene model reviewed during 5.50
None of the polypeptides share 100% sequence identity.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\DAT using the Feature Mapper tool.
Comment: anlage in statu nascendi
Comment: reported as procephalic ectoderm anlage in statu nascendi
Comment: reported as procephalic ectoderm anlage in statu nascendi
Comment: reported as procephalic ectoderm anlage in statu nascendi
Comment: Thorax and abdomen assayed together.
Comment: Thorax and abdomen assayed together.
Comment: 12-24 hr AEL; not expressed 4-12 hr AEL
In situ hybridization in third instar larvae show that DAT is expressed in dopaminergic (DA) neurons. In the brain, it is observed in three DA neuron cell groups in each lobe. In the ventral nerve cord, it is seen in eight unpaired medial DA neurons along the midline and in two rows of seven dorsal lateral DA neurons. A developmental profile done by RT-PCR show robust expression in late embryos and larvae, a dip in expression in pupae and an increase in adults, with heads showing enhanced signal over bodies.
GBrowse - Visual display of RNA-Seq signals
View Dmel\DAT in GBrowse 2Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
monoclonal
Source for merge of: DAT CG8380
Source for merge of DAT CG8380 was sequence comparison ( date:000622 ).
The elimination of DAT activity generates a dramatic increase in the length of the active (waking) phase and a corresponding reduction of the inactive phase (sleep or rest), resulting a a nearly sleepless phenotype.
Called 'fumin' (fmn), meaning 'sleepless' in Japanese.