Gene model reviewed during 5.39
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.52
None of the polypeptides share 100% sequence identity.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Eps-15 using the Feature Mapper tool.
Eps-15 is expressed in central brain neuropils. It is uniformly high amongst the different neuropils. In cross sections of the lamina, Eps-15 labelling reveals the outline of photoreceptor R1-R6 terminals, and particularly strong staining was seen at the sites facing the interior of the cartridge. Via immunoelectron microscopy, Eps-15 is seen amongst the vesicle pool in the cytoplasm of the photoreceptors, and often close to the capitate projection (invaginations from surrounding epithelial glial and specialised organelles for the endocytosis of vesicle membrane).
GBrowse - Visual display of RNA-Seq signalsView Dmel\Eps-15 in GBrowse 2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: Eps-15 CG16932
Source for merge of: Eps-15 anon-WO0118547.85
Source for merge of Eps-15 anon-WO0118547.85 was sequence comparison ( date:051113 ).
dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology.
Area matching Drosophila EST AI260872 (inverted). This EST has sequence similarity to mouse signalling factor U29156.