FlyBase Gene Report: Dmel\Pex7

General Information

Symbol

Dmel\Pex7

Species

D. melanogaster

Name

Peroxin 7

Annotation Symbol

CG6486

Feature Type

protein_coding_gene

FlyBase ID

FBgn0035922

Gene Model Status

Current

Stock Availability

6 publicly available

Gene Summary

Contribute a Gene Snapshot for this gene.

All Summaries

Alliance
Auto summary
Gene Group
Interactive Fly

Key Links

Genomic Location

Cytogenetic map

66D9-66D10

Sequence location

3L:8,647,145..8,651,011 [+]

Recombination map

3-26

RefSeq locus

NT_037436 REGION:8647145..8651011

Sequence

Get Decorated FASTA

Genomic Maps

JBrowse

Other Genome Views

The following external sites may use different assemblies or annotations than FlyBase.

Function

Gene Ontology (GO) Annotations (6 terms)

Molecular Function (1 term)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (1 term)

CV Term

Evidence

References

enables peroxisome matrix targeting signal-2 binding

inferred from biological aspect of ancestor with PANTHER:PTN000522958

(GO Reference Genome Project, 2011-)

inferred from electronic annotation with InterPro:IPR044536

(InterPro Project Members, 2004-)

Biological Process (2 terms)

Terms Based on Experimental Evidence (1 term)

CV Term

Evidence

References

involved_in protein import into peroxisome matrix

inferred from genetic interaction with UniProtKB:O00628

(Di Cara et al., 2019)

Terms Based on Predictions or Assertions (2 terms)

CV Term

Evidence

References

involved_in peroxisome organization

inferred from sequence or structural similarity with UniProtKB:O00628

(Faust et al., 2012)

involved_in protein import into peroxisome matrix

inferred from electronic annotation with InterPro:IPR044536

(InterPro Project Members, 2004-)

inferred from biological aspect of ancestor with PANTHER:PTN000522958

(GO Reference Genome Project, 2011-)

Cellular Component (3 terms)

Terms Based on Experimental Evidence (2 terms)

CV Term

Evidence

References

located_in cytosol

inferred from direct assay

(Baron et al., 2016)

located_in peroxisome

inferred from direct assay

(Baron et al., 2016)

Terms Based on Predictions or Assertions (3 terms)

CV Term

Evidence

References

is_active_in cytosol

inferred from biological aspect of ancestor with PANTHER:PTN000522958

(GO Reference Genome Project, 2011-)

is_active_in peroxisomal matrix

inferred from biological aspect of ancestor with PANTHER:PTN000522958

(GO Reference Genome Project, 2011-)

located_in peroxisome

inferred from sequence or structural similarity with UniProtKB:O00628

(Faust et al., 2012)

Gene Group (FlyBase)

PEROXINS

PEROXISOMAL TARGETING SYSTEM COMPONENTS

Protein Family (UniProt)

Protein Signatures (InterPro)

Summaries

Gene Group (FlyBase)

PEROXINS -: Peroxisomes are eukaryotic organelles critical for the metabolism of fatty acids, particularly very-long-chain fatty acids, and other metabolites. The peroxin genes encode proteins required for peroxisome biogenesis. (Adapted from FBrf0209624).
PEROXISOMAL TARGETING SYSTEM COMPONENTS -: The peroxisomal targeting system mediates the import of cytoplasmic translated proteins into the peroxisome or their insertion into the peroxisome membrane.

Gene Model and Products

Number of Transcripts

Number of Unique Polypeptides

Please see the JBrowse view of Dmel\Pex7 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Structure

Protein 3D structure (Predicted by AlphaFold) (AlphaFold entry Q9VSN7)

If you don't see a structure in the viewer, refresh your browser.

Model Confidence:

Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Experimentally Determined Structures

Crossreferences

Comments on Gene Model

Gene model reviewed during 5.46

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Assoc. CDS (aa)

Pex7-RA

FBtr0076568

NM_139994

1443

339

Pex7-RB

FBtr0273328

NM_001144442

1391

339

Additional Transcript Data and Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

UniProt

RefSeq ID

GenBank

Pex7-PA

FBpp0076295

37.6

339

4.89

FBpp0271836

37.6

339

4.89

Q9VSN7

NP_001137914

ACL83269

Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

339 aa isoforms: Pex7-PA, Pex7-PB

Additional Polypeptide Data and Comments

Reported size (kDa)

Comments

External Data

Crossreferences

InterPro - A database of protein families, domains and functional sites

Linkouts

Sequences Consistent with the Gene Model

Nucleotide / Polypeptide Records

UniProt

Q9VSN7

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Pex7 using the Feature Mapper tool.

External Data

Crossreferences

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

Linkouts

Expression Data

Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

-0.33

Transcript Expression

in situ

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 4

yolk

(Pridie and Simmonds, 2021)

embryonic cortex

(Pridie and Simmonds, 2021)

embryonic stage 9 -- 12

supraesophageal ganglion

(Pridie and Simmonds, 2021)

embryonic stage 9 -- 17

ventral nerve cord | restricted

(Pridie and Simmonds, 2021)

Additional Descriptive Data

A high level of Pex7 FISH signal is observed in the yolk and at the cortex of the syncytial blastoderm and persists during gastrulation. A time course from 2-22hr AEL was carried out. Roughly 30 min. after the maternal-zygotic transition (MZT) of gene transcription at 1.5 h AEL, a weak, variable signal of Pex7 FISH is observed in the yolk at the center of the embryo. These foci are cortically perinuclear in embryos just before syncytial cellularization and then became ubiquitous following formation of the anterior-posterior axis and cephalization. At 8-12h AEL, Pex7 transcription is restricted to the presumptive supraesophageal ganglion and ventral nerve cord. This pattern persists until 16-20h AEL, when Pex7 mRNA expression is also observed in cells on the cortical layer of the CNS in a pattern most similar to neuroblasts. Immediately prior to hatching (20-22 h AEL), the Pex7 mRNA pattern was observed to be restricted to the anterior half of the presumptive nerve cord and primitive optic lobes, with fewer overall foci observed compared to prior time points.

(Pridie and Simmonds, 2021)

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

immunolocalization

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage

yolk

(Pridie and Simmonds, 2021)

embryonic stage 9

organism | ubiquitous

(Pridie and Simmonds, 2021)

embryonic stage 15 -- 17

ventral nerve cord | restricted

(Pridie and Simmonds, 2021)

Additional Descriptive Data

The Pex7 protein expression pattern is similar to the mRNA pattern. Signal is observed in both the yolk and the pre-cellular syncytium. At the completion of germ band elongation, signal becomes ubiquitous. Comparison to markers shows the folowing: Cells showing strong Pex7 signal are found in cells adjacent to elav expressing cells at 7.3-9.7hr AEL. At 12hr AEL, a pattern is observed characterized by para-segmental repeats of five small distinct branches and two foci adjacent to the ventral nerve cord. Some cells in the extreme anterior/posterior regions also express Pex7 but these do not overlap with the Nrg- or repo-expressing cells. At 16hr AEL, strong signal is observed in a subset of cells on the cortical layer of the CNS. At all subsequent stages, signal is restricted to the ventral nerve cord.

(Pridie and Simmonds, 2021)

Marker for

Subcellular Localization

CV Term

Evidence

References

located_in cytosol

inferred from direct assay

(Baron et al., 2016)

located_in peroxisome

inferred from direct assay

(Baron et al., 2016)

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\Pex7 in JBrowse

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\Pex7

View exonic expression by tissue for Dmel\Pex7

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

38994/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0035922

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0035922

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0035922

Flygut - An atlas of the Drosophila adult midgut

FBgn0035922

Images

FlyBase Wiki

Image Based Resources

Alleles, Insertions, Transgenic Constructs, and Aberrations

Classical and Insertion Alleles ( 1 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 5 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of Pex7

Transgenic constructs containing regulatory region of Pex7

Aberrations (Deficiencies and Duplications) ( 1 )

Inferred from experimentation ( 1 )

Gene partially disrupted in

Df(3L)CRIMIC-CR71122

(Gene Disruption Project members, 2018-)

Inferred from location ( 4 )

Variants

Variant Molecular Consequences

Alleles Representing Disease-Implicated Variants

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

partially lethal, with Scer\GAL4^Act5C.PU

Pex7^UASp.cPa

partially lethal, with Scer\GAL4^elav-C155

Pex7^TKO.GS00766

viable

Pex7^MI14471

viable, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

Pex7^GD11937

viable, with Scer\GAL4^Mef2.PR

Pex7^GD11937

viable, with Scer\GAL4^pnr-MD237

Pex7^GD11937

viable, with Scer\GAL4^tin.CΔ4

Pex7^GD11937

viable (with Df(3L)BSC816)

Pex7^MI14471

Other Phenotypes

Allele

abnormal body color, with Scer\GAL4^pnr-MD237

Pex7^GD11937

abnormal neurophysiology | third instar larval stage

Pex7^MI14471

abnormal neurophysiology | third instar larval stage (with Df(3L)BSC816)

Pex7^MI14471

abnormal size | third instar larval stage

Pex7^MI14471

abnormal size | third instar larval stage (with Df(3L)BSC816)

Pex7^MI14471

decreased fecundity, with Scer\GAL4^elav-C155

increased body size | larval stage

Pex7^MI14471

increased cell death | embryonic stage 15

Pex7^MI14471

increased cell death | third instar larval stage

Pex7^MI14471

increased cell death | third instar larval stage (with Df(3L)BSC816)

Pex7^MI14471

some die during P-stage

Pex7^MI14471

some die during P-stage (with Df(3L)BSC816)

Pex7^MI14471

Phenotype manifest in

Allele

larval brain | third instar larval stage

Pex7^MI14471

larval brain | third instar larval stage (with Df(3L)BSC816)

Pex7^MI14471

mesonotum, with Scer\GAL4^pnr-MD237

Pex7^GD11937

pupa

Pex7^MI14471

pupa (with Df(3L)BSC816)

Pex7^MI14471

Orthologs

Downloads

Download All DIOPT Orthologs

Human Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Homo sapiens (Human) (50)

Hsap\PEX7

13 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Model Organism Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Rattus norvegicus (Norway rat) (32)

Rnor\Pex7

13 of 14

Yes

Rnor\Atg16l1

1 of 14

Rnor\Ciao1

1 of 14

Rnor\Cop1

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Mus musculus (laboratory mouse) (31)

Mmus\Pex7

12 of 14

Yes

Mmus\Atg16l1

1 of 14

Mmus\Ciao1

1 of 14

Mmus\Cop1

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

Xenopus tropicalis (Western clawed frog) (29)

Xtro\pex7

3 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Yes

Danio rerio (Zebrafish) (32)

Drer\pex7

13 of 14

Yes

Drer\cop1

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Caenorhabditis elegans (Nematode, roundworm) (13)

Cele\dyci-1

1 of 14

Yes

Cele\gad-1

1 of 14

Yes

Cele\JC8.2

1 of 14

Yes

Cele\lin-53

1 of 14

Yes

Cele\prp-4

1 of 14

Yes

Cele\rba-1

1 of 14

Yes

Cele\snrp-40.1

1 of 14

Yes

Cele\snrp-40.2

1 of 14

Yes

Cele\swan-1

1 of 14

Yes

Cele\swan-2

1 of 14

Yes

Cele\Y32H12A.8

1 of 14

Yes

Cele\Y43F4B.9

1 of 14

Yes

Cele\Y54H5A.1

1 of 14

Yes

Anopheles gambiae (African malaria mosquito) (27)

Agam\AgaP_AGAP006264

10 of 12

Yes

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

Arabidopsis thaliana (thale-cress) (36)

Atha\PEX7

12 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Yes

Atha\SPA2

1 of 13

Yes

Atha\SPA3

1 of 13

Yes

Atha\SPA4

1 of 13

Yes

Atha\TOZ

1 of 13

Atha\TTG1

1 of 13

Atha\VIP3

1 of 13

Saccharomyces cerevisiae (Brewer's yeast) (17)

Scer\PEX7

10 of 13

Yes

2 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Schizosaccharomyces pombe (Fission yeast) (15)

Spom\pex7

10 of 12

Yes

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

Escherichia coli (enterobacterium) (0)

Other Organism Orthologs (via OrthoDB)

Data provided directly from OrthoDB:Pex7. Refer to their site for version information.

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v9.1)

Gene Symbol

Score

Source

Alignment

Drosophila melanogaster (Fruit fly) (34)

2 of 13

2 of 13

2 of 13

2 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

fzr

1 of 13

nclb

1 of 13

Nle

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

vls

1 of 13

wap

1 of 13

Wdr33

1 of 13

Wdr37

1 of 13

wds

1 of 13

Human Disease Associations

FlyBase Human Disease Model Reports

peroxisome biogenesis disorder 9B

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 1 )

Allele

Disease

Evidence

References

Pex7^MI14471

model of Peroxisome biogenesis disorder 9B

CEC

(Di Cara et al., 2019)

Potential Models Based on Orthology ( 2 )

Human Ortholog

Disease

Evidence

References

PEX7; peroxisomal biogenesis factor 7

model of rhizomelic chondrodysplasia punctata type 1

IEA

(FlyBase, 2019-)

model of Peroxisome biogenesis disorder 9B

IEA

(FlyBase, 2019-)

Modifiers Based on Experimental Evidence ( 0 )

Allele

Disease

Interaction

References

Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

PEX7; peroxisomal biogenesis factor 7

13 of 14

601757

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

Interaction Browsers

Summary of Genetic Interactions

Interaction Browsers

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

External Data

Linkouts

BioGRID - A database of protein and genetic interactions.

64401

DroID - A comprehensive database of gene and protein interactions.

FBgn0035922

MIST (protein-protein) - An integrated Molecular Interaction Database

38994

Pathways

Signaling Pathways (FlyBase)

Metabolic Pathways

FlyBase

External Links

External Data

Linkouts

KEGG Pathways - A collection of manually drawn pathway maps representing knowledge of molecular interaction, reaction and relation networks.

Peroxisome

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

Peroxisomal protein import

SignaLink - A signaling pathway resource with multi-layered regulatory networks.

Q9VSN7

Class of Gene

nuclear_gene

protein_coding_gene

Genomic Location and Detailed Mapping Data

Chromosome (arm)

Recombination map

3-26

Cytogenetic map

66D9-66D10

Sequence location

3L:8,647,145..8,651,011 [+]

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

66D9-66D10

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

3-26

(FlyBase, 2016)

3-20.5

(Comeron et al., 2012)

Left of (cM)

Right of (cM)

Notes

Stocks and Reagents

Stocks (6)

Aberrations including deletions of this gene Aberrations including duplications of this gene

Bloomington

601134

w¹¹¹⁸; P{VT027671-p65.AD}attP40

59520

y¹ w^*; Mi{MIC}Pex7^MI14471

76994

y¹ sc^* v¹ sev²¹; P{TKO.GS00766}attP40

Korea

15150

P{VT027671-GAL4}attP2

VDRC

v108795

P{KK102648}VIE-260B

v43804

w¹¹¹⁸; P{GD11937}v43804

Genomic Clones (15)

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (7)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced

BDGP DGC clones

Other clones

FI16637

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

FBgn0035922

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi and Array Information

Linkouts

DRSC - Results frm RNAi screens

FBgn0035922

Antibody Information

Laboratory Generated Antibodies

polyclonal

(Pridie and Simmonds, 2021)

Commercially Available Antibodies

Cell Line Information

Publicly Available Cell Lines

Other Stable Cell Lines

Other Comments

S2 cells treated with dsRNA generated against this gene show reduced phagocytosis of Candida albicans compared to untreated cells.

(Stroschein-Stevenson et al., 2006)

Relationship to Other Genes

Source for database merge of

Additional comments

Nomenclature History

Source for database identify of

Source for identity of: Pex7 CG6486

(Mast et al., 2011)

Nomenclature comments

Etymology

Synonyms and Secondary IDs (6)

Reported As

Symbol Synonym

CG6486

(Pegoraro et al., 2022, Baron et al., 2016, Faust et al., 2012, Faust et al., 2012, Mast et al., 2011, Keleman et al., 2009.8.5, Stroschein-Stevenson et al., 2006)

DmelPex7

(Mast et al., 2011)

PEX&

(Anderson-Baron and Simmonds, 2018)

PEX7

(Baron et al., 2016, Oortveld et al., 2013, Faust et al., 2012)

Pex7

(Li et al., 2023, Hagen et al., 2021, Pridie and Simmonds, 2021, Pridie et al., 2020, Di Cara et al., 2019, Anderson-Baron and Simmonds, 2018, Transgenic RNAi Project members, 2017-, Mast et al., 2011)

Name Synonyms

Peroxin 7

(Anderson-Baron and Simmonds, 2018)

Secondary FlyBase IDs

Datasets (0)

Study focus (0)

Experimental Role

Project

Project Type

Title

Study result (0)

Result

Result Type

Title

External Crossreferences and Linkouts ( 37 )

Sequence Crossreferences

NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

38994

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.

UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.

Q9VSN7

UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information

Q9VSN7

Other crossreferences

AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.

Q9VSN7

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

38994/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0035922

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0035922

FlyMine - An integrated database for Drosophila genomics

FBgn0035922

InterPro - A database of protein families, domains and functional sites

KEGG Genes - Molecular building blocks of life in the genomic space.

dme:Dmel_CG6486

MARRVEL_MODEL - MARRVEL (model organism gene)

38994

Linkouts

BioGRID - A database of protein and genetic interactions.

64401

Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones

FBgn0035922

DroID - A comprehensive database of gene and protein interactions.

FBgn0035922

DRSC - Results frm RNAi screens

FBgn0035922

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0035922

FlyCyc Genes - Genes from a BioCyc PGDB for Dmel

FBGN0035922

Flygut - An atlas of the Drosophila adult midgut

FBgn0035922

FlyMet - A comprehensive tissue-specific metabolomics resource for Drosophila.

FBgn0035922

iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)

TC011845

KEGG Pathways - A collection of manually drawn pathway maps representing knowledge of molecular interaction, reaction and relation networks.

Peroxisome

MIST (protein-protein) - An integrated Molecular Interaction Database

38994

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

Peroxisomal protein import

SignaLink - A signaling pathway resource with multi-layered regulatory networks.

Q9VSN7

References (36)

The following external sites may use different assemblies or annotations than FlyBase.

-0.33

Report Sections