FlyBase Gene Report: Dmel\Aps

General Information

Symbol

Dmel\Aps

Species

D. melanogaster

Name

Aps

Annotation Symbol

CG6391

Feature Type

protein_coding_gene

FlyBase ID

FBgn0036111

Gene Model Status

Current

Stock Availability

7 publicly available

Gene Summary

Aps (Aps) encodes a diphosphoinositol-polyphosphate diphosphatase that hydrolyses a range of (di)nucleoside polyphosphates. It is involved in glucose and lipid homeostasis. [Date last reviewed: 2019-09-12] (FlyBase Gene Snapshot)

All Summaries

Gene Snapshot
Alliance
Auto summary
Gene Group
Interactive Fly

Key Links

Genomic Location

Cytogenetic map

67F1-67F1

Sequence location

3L:10,894,776..10,899,123 [-]

Recombination map

3-33

RefSeq locus

NT_037436 REGION:10894776..10899123

Sequence

Get Decorated FASTA

Genomic Maps

JBrowse GBrowse

Help me choose

Other Genome Views

The following external sites may use different assemblies or annotations than FlyBase.

Function

GO Summary Ribbons

Gene Ontology (GO) Annotations (17 terms)

Molecular Function (6 terms)

Terms Based on Experimental Evidence (2 terms)

CV Term

Evidence

References

enables bis(5'-adenosyl)-hexaphosphatase activity

inferred from direct assay

(Winward et al., 2010)

enables inositol diphosphate pentakisphosphate diphosphatase activity

inferred from direct assay

(Winward et al., 2010)

Terms Based on Predictions or Assertions (5 terms)

CV Term

Evidence

References

enables bis(5'-adenosyl)-hexaphosphatase activity

inferred from biological aspect of ancestor with PANTHER:PTN000290327

(assigned by GO_Central )

(Gaudet et al., 2011)

enables bis(5'-adenosyl)-pentaphosphatase activity

inferred from biological aspect of ancestor with PANTHER:PTN000290327

(assigned by GO_Central )

(Gaudet et al., 2011)

enables diphosphoinositol-polyphosphate diphosphatase activity

inferred from biological aspect of ancestor with PANTHER:PTN000290327

(assigned by GO_Central )

(Gaudet et al., 2011)

enables endopolyphosphatase activity

inferred from biological aspect of ancestor with PANTHER:PTN000290327

(assigned by GO_Central )

(Gaudet et al., 2011)

enables m7G(5')pppN diphosphatase activity

inferred from biological aspect of ancestor with PANTHER:PTN000290327

(assigned by GO_Central )

(Gaudet et al., 2011)

Biological Process (9 terms)

Terms Based on Experimental Evidence (5 terms)

CV Term

Evidence

References

involved_in glucose homeostasis

inferred from mutant phenotype

(Williams et al., 2015)

involved_in inositol phosphate metabolic process

inferred from direct assay

(Winward et al., 2010)

involved_in lipid homeostasis

inferred from mutant phenotype

(Williams et al., 2015)

involved_in nucleotide metabolic process

inferred from direct assay

(Winward et al., 2010)

involved_in response to starvation

inferred from mutant phenotype

(Williams et al., 2015)

Terms Based on Predictions or Assertions (4 terms)

CV Term

Evidence

References

involved_in adenosine 5'-(hexahydrogen pentaphosphate) catabolic process

inferred from biological aspect of ancestor with PANTHER:PTN000290327

(assigned by GO_Central )

(Gaudet et al., 2011)

involved_in diadenosine hexaphosphate catabolic process

inferred from biological aspect of ancestor with PANTHER:PTN000290327

(assigned by GO_Central )

(Gaudet et al., 2011)

involved_in diadenosine pentaphosphate catabolic process

inferred from biological aspect of ancestor with PANTHER:PTN000290327

(assigned by GO_Central )

(Gaudet et al., 2011)

involved_in diphosphoinositol polyphosphate metabolic process

inferred from biological aspect of ancestor with PANTHER:PTN000290327

(assigned by GO_Central )

(Gaudet et al., 2011)

Cellular Component (2 terms)

Terms Based on Experimental Evidence (2 terms)

CV Term

Evidence

References

located_in cytoplasm

inferred from direct assay

(Winward et al., 2010)

located_in nucleus

inferred from direct assay

(Winward et al., 2010)

Terms Based on Predictions or Assertions (2 terms)

CV Term

Evidence

References

located_in cytoplasm

inferred from biological aspect of ancestor with PANTHER:PTN000290326

(assigned by GO_Central )

(Gaudet et al., 2011)

located_in nucleus

inferred from biological aspect of ancestor with PANTHER:PTN000290326

(assigned by GO_Central )

(Gaudet et al., 2011)

Gene Group (FlyBase)

NUCLEOTIDE DIPHOSPHATASES

RNA DECAPPING ENZYMES

Protein Family (UniProt)

Protein Signatures (InterPro)

Summaries

Gene Snapshot

Gene Group (FlyBase)

NUCLEOTIDE DIPHOSPHATASES -: Nucleotide diphosphatases catalyze the hydrolysis of a dinucleotide (e.g. FAD, NAD+, NADH) to produce 2 mononucleotides.
RNA DECAPPING ENZYMES -: RNA decapping enzymes catalyze the removal of the 5'-5' linked N7-methyl guanosine (m7G) cap that is present on most eukaryotic mRNAs and small nuclear RNAs. This exposes the 5' end of the RNA to nucleases and thereby enables RNA turnover. Dependent on the direction of the RNA decay pathway, some enzymes cleave the 5' -> 5' cap linkage of intact RNAs to initiate decay, while others act as scavengers and hydrolyse the cap element of the remnants of the 3' -> 5' decay pathway. In eukaryotes, there is also a cap quality control pathway that selectively degrade mRNAs with a faulty cap. (Adapted from PMID:30345629.)

Gene Model and Products

Number of Transcripts

Number of Unique Polypeptides

Please see the JBrowse view of Dmel\Aps for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Comments on Gene Model

Gene model reviewed during 5.55

Gene model reviewed during 5.46

Annotated transcripts do not represent all supported alternative splices within 5' UTR.

Sequence Ontology: Class of Gene

nuclear_gene

protein_coding_gene

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Assoc. CDS (aa)

Aps-RA

FBtr0076250

NM_140164

2565

177

Aps-RB

FBtr0076251

NM_168425

2364

177

Aps-RC

FBtr0076252

NM_168426

2744

177

Additional Transcript Data and Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

RefSeq ID

GenBank

Aps-PA

FBpp0075979

19.9

177

5.95

NP_648421

AAN11888

Aps-PB

FBpp0075980

19.9

177

5.95

NP_729639

AAF50123

Aps-PC

FBpp0075981

19.9

177

5.95

NP_729640

AAN11889

Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

177 aa isoforms: Aps-PA, Aps-PB, Aps-PC

Additional Polypeptide Data and Comments

Reported size (kDa)

Comments

External Data

Crossreferences

InterPro - A database of protein families, domains and functional sites

Linkouts

Sequences Consistent with the Gene Model

Nucleotide / Polypeptide Records

UniProt

Q7JVG2

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Aps using the Feature Mapper tool.

External Data

Crossreferences

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

Aps_1

Linkouts

Expression Data

Expression Summary Ribbons

Colored tiles in ribbon indicate that expression data has been curated by FlyBase for that anatomical location. Colorless tiles indicate that there is no curated data for that location.

For complete stage-specific expression data, view the modENCODE Development RNA-Seq section under High-Throughput Expression below.

Transcript Expression

in situ

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 1 -- 3

organism

Comment: maternally deposited

(Fisher et al., 2012)

embryonic stage 4 -- 6

organism

(Fisher et al., 2012)

embryonic stage 7 -- 8

organism | ubiquitous

(Fisher et al., 2012)

embryonic stage 9 -- 10

organism | ubiquitous

(Fisher et al., 2012)

embryonic stage 13 -- 16

embryonic brain

(Fisher et al., 2012)

embryonic central brain neuron

(Fisher et al., 2012)

embryonic hindgut

(Fisher et al., 2012)

embryonic Malpighian tubule

(Fisher et al., 2012)

embryonic/larval midgut

(Fisher et al., 2012)

organism | ubiquitous

(Fisher et al., 2012)

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Evidence

References

located_in cytoplasm

inferred from direct assay

(Winward et al., 2010)

located_in nucleus

inferred from direct assay

(Winward et al., 2010)

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

GBrowse - Visual display of RNA-Seq signals

View Dmel\Aps in GBrowse 2

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\Aps

View exonic expression by tissue for Dmel\Aps

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0036111

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

FBgn0036111

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

CG6391-RA

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG6391

Flygut - An atlas of the Drosophila adult midgut

FBgn0036111

Images

FlyExpress - Embryonic expression images (BDGP data)

Show all FlyExpress processed images for Dmel\Aps

Stages(s) 4-6
Stages(s) 7-8
Stages(s) 9-10
Stages(s) 11-12
Stages(s) 13-16

FlyBase Wiki

Image Based Resources

Alleles, Insertions, Transgenic Constructs, and Aberrations

Classical and Insertion Alleles ( 6 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 7 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of Aps

Transgenic constructs containing regulatory region of Aps

Aberrations (Deficiencies and Duplications) ( 0 )

Inferred from experimentation ( 0 )

Inferred from location ( 0 )

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

viable, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

Aps^GD10570

viable, with Scer\GAL4^pnr-MD237

Aps^GD10570

viable, with Scer\GAL4^tin.CΔ4

Aps^GD10570

Other Phenotypes

Allele

abnormal starvation stress response, with Scer\GAL4^elav-C155

abnormal starvation stress response, with Scer\GAL4^Ilp2.PR

Aps^KK108331

Phenotype manifest in

Allele

Orthologs

Downloads

Download All DIOPT Orthologs

Download All OrthoDB Orthologs

Human Orthologs (via DIOPT v8.0)

Homo sapiens (Human) (14)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Hsap\NUDT4

13 of 15

Yes

Hsap\NUDT11

13 of 15

Yes

Hsap\NUDT3

12 of 15

Yes

Hsap\NUDT10

12 of 15

Yes

Hsap\NUDT4B

4 of 15

Yes

Hsap\RPS10-NUDT3

2 of 15

Hsap\DCP2

1 of 15

Hsap\NUDT1

1 of 15

Yes

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

Model Organism Orthologs (via DIOPT v8.0)

Mus musculus (laboratory mouse) (12)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Mmus\Nudt3

13 of 15

Yes

Mmus\Nudt4

12 of 15

Yes

Mmus\Nudt11

12 of 15

Yes

Mmus\Nudt10

9 of 15

Yes

Mmus\Dcp2

1 of 15

Mmus\Nudt1

1 of 15

Yes

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

Rattus norvegicus (Norway rat) (10)

Rnor\Nudt4

12 of 13

Yes

Rnor\Nudt10

11 of 13

Yes

Rnor\Nudt3

9 of 13

Yes

Rnor\Nudt11

5 of 13

Yes

Rnor\Nudt1

1 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Xenopus tropicalis (Western clawed frog) (7)

Xtro\nudt4

12 of 12

Yes

Xtro\dcp2

1 of 12

Xtro\nudt1

1 of 12

Yes

1 of 12

1 of 12

1 of 12

1 of 12

Danio rerio (Zebrafish) (13)

Drer\nudt3b

13 of 15

Yes

Drer\nudt4a

13 of 15

Yes

Drer\nudt4b

13 of 15

Yes

Drer\nudt3a

10 of 15

Yes

Drer\dcp2

1 of 15

Drer\nudt1

1 of 15

Yes

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

Caenorhabditis elegans (Nematode, roundworm) (9)

Cele\Y92H12BL.5

14 of 15

Yes

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

Arabidopsis thaliana (thale-cress) (7)

Atha\NUDT16

8 of 9

Yes

Atha\NUDT4

7 of 9

Yes

Atha\NUDT21

7 of 9

Yes

Atha\NUDT12

6 of 9

Yes

Atha\NUDT17

6 of 9

Yes

Atha\NUDT18

6 of 9

Yes

Atha\NUDX13

5 of 9

Yes

Saccharomyces cerevisiae (Brewer's yeast) (5)

Scer\DDP1

11 of 15

Yes

1 of 15

1 of 15

1 of 15

1 of 15

Schizosaccharomyces pombe (Fission yeast) (1)

Spom\aps1

8 of 12

Yes

Ortholog(s) in Drosophila Species (via OrthoDB v9.1) ( EOG09190HHA )

Organism

Common Name

Gene

AAA Syntenic Ortholog

Multiple Dmel Genes in this Orthologous Group

Drosophila suzukii

Spotted wing Drosophila

Drosophila simulans

Drosophila sechellia

Drosophila erecta

Drosophila yakuba

Drosophila ananassae

Drosophila pseudoobscura pseudoobscura

Dpse\GA19558

Drosophila persimilis

Dper\GL11750

Drosophila willistoni

Dwil\GK18021

Drosophila virilis

Dvir\GJ11730

Drosophila mojavensis

Dmoj\GI13875

Drosophila grimshawi

Dgri\GH16579

Orthologs in non-Drosophila Dipterans (via OrthoDB v9.1) ( EOG09150EO9 )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Musca domestica

House fly

Mdoa\17004624

Glossina morsitans

Tsetse fly

Gmor\GMOY008656

Lucilia cuprina

Australian sheep blowfly

Lcup\FF38_01134

Mayetiola destructor

Hessian fly

Mdes\Mdes008111

Aedes aegypti

Yellow fever mosquito

Aaeg\AAEL003678

Anopheles darlingi

American malaria mosquito

Adar\ADAC000873

Anopheles gambiae

Malaria mosquito

Agam\AGAP009901

Culex quinquefasciatus

Southern house mosquito

Cqui\CPIJ011443

Orthologs in non-Dipteran Insects (via OrthoDB v9.1) ( EOG090W0I5S )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Bombyx mori

Silkmoth

Bmor\BGIBMGA011973

Danaus plexippus

Monarch butterfly

Dple\DPOGS210332-PA

Heliconius melpomene

Postman butterfly

Hmel\HMEL013837

Apis florea

Little honeybee

Aflo\2737899124

Apis mellifera

Western honey bee

Amel\Aps

Bombus impatiens

Common eastern bumble bee

Bimp\BIMP20319

Bombus terrestris

Buff-tailed bumblebee

Bter\15202808

Linepithema humile

Argentine ant

Lhum\LH11396

Megachile rotundata

Alfalfa leafcutting bee

Mrot\MROTU:000eff

Nasonia vitripennis

Parasitic wasp

Nvit\Nasvi2EG012341

Tribolium castaneum

Red flour beetle

Tcas\TC003674

Pediculus humanus

Human body louse

Phum\PHUM041410

Rhodnius prolixus

Kissing bug

Rpro\RPRC009512

Cimex lectularius

Bed bug

Clec\CLEC007505

Acyrthosiphon pisum

Pea aphid

Apim\ACYPI002733

Zootermopsis nevadensis

Nevada dampwood termite

Znev\Znev_12133

Orthologs in non-Insect Arthropods (via OrthoDB v9.1) ( EOG090X0I98 )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Strigamia maritima

European centipede

Smar\SMAR006938

Ixodes scapularis

Black-legged tick

Isca\ISCW020460

Stegodyphus mimosarum

African social velvet spider

Smim\KFM58394.1

Tetranychus urticae

Two-spotted spider mite

Turt\tetur30g01520

Daphnia pulex

Water flea

Dpux\DAPPUDRAFT_300631

Orthologs in non-Arthropod Metazoa (via OrthoDB v9.1) ( EOG091G0TH6 )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Strongylocentrotus purpuratus

Purple sea urchin

Spur\Sp-Nudt3

Ciona intestinalis

Vase tunicate

Cint\LOC100182773

Gallus gallus

Domestic chicken

Ggal\NUDT3

Gallus gallus

Domestic chicken

Ggal\NUDT4

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v8.0)

Drosophila melanogaster (Fruit fly) (9)

Gene Symbol

Score

Source

Alignment

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

Human Disease Associations

FlyBase Human Disease Model Reports

insulin pathway effects, NUDT-related

Disease Model Summary Ribbon

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 0 )

Human Ortholog

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Allele

Disease

Interaction

References

Disease Associations of Human Orthologs (via DIOPT v8.0 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

NUDT4; nudix hydrolase 4

13 of 15

609229

NUDT11; nudix hydrolase 11

13 of 15

300528

NUDT3; nudix hydrolase 3

12 of 15

609228

NUDT10; nudix hydrolase 10

12 of 15

300527

NUDT4B; nudix hydrolase 4B

4 of 15

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

esyN Network Diagram

Interactions Browser

Summary of Genetic Interactions

esyN Network Diagram

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

External Data

Linkouts

DroID - A comprehensive database of gene and protein interactions.

FBgn0036111

InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.

39226

Pathways

Signaling Pathways (FlyBase)

Metabolic Pathways

External Data

Linkouts

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

Synthesis of pyrophosphates in the cytosol

Genomic Location and Detailed Mapping Data

Chromosome (arm)

Recombination map

3-33

Cytogenetic map

67F1-67F1

Sequence location

3L:10,894,776..10,899,123 [-]

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

67F1-67F1

Limits computationally determined from genome sequence between P{lacW}tna^L6731 and P{PZ}klu⁰⁹⁰³⁶

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

3-33

(FlyBase, 2016)

3-27.5

(Comeron et al., 2012)

Left of (cM)

Right of (cM)

Notes

Stocks and Reagents

Stocks (7)

Bloomington

12439

w¹¹¹⁸; P{GT1}Aps^BG00831

83525

y¹ sc^* v¹ sev²¹; P{TKO.GS04284}attP40

50651

y¹ sc^* v¹ sev²¹; P{TRiP.HMC03052}attP2

Kyoto

103540

y^* w^*; P{GawB}Aps^NP0150 / TM6, P{UAS-lacZ.UW23-1}UW23-1

VDRC

v109431

P{KK108331}VIE-260B

v110607

P{KK109021}VIE-260B

v341941

P{hsFLP}1, y¹ w¹¹¹⁸; P{HD_CFD01222}attP40/CyO-GFP

Genomic Clones (15)

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (297)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced

BDGP DGC clones

Other clones

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

FBgn0036111

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi and Array Information

Linkouts

DRSC - Results frm RNAi screens

FBgn0036111

GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents

39226

Antibody Information

Laboratory Generated Antibodies

Commercially Available Antibodies

Other Information

Relationship to Other Genes

Source for database identify of

Source for identity of: Aps CG6391

(Safrany, 2004.11.15)

Source for database merge of

Source for merge of: Aps anon-WO0118547.266

(FlyBase, 1996-)

Additional comments

l(3)s2714 may correspond to Aps: the P{lacW}l(3)s2714^s2714 insertion maps within the transcription unit.

(Gene Disruption Project members, 2015.10.8)

Source for merge of Aps anon-WO0118547.266 was sequence comparison ( date:051113 ).

(FlyBase, 1996-)

Other Comments

Area matching Drosophila ESTs AA539914 and AA201959 (1042bp contig).

(Davies, 2001.3.15)

Origin and Etymology

Discoverer

Etymology

Identification

External Crossreferences and Linkouts ( 49 )

Sequence Crossreferences

NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

39226

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.

UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information

Q7JVG2

Other crossreferences

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0036111

Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones

FBgn0036111

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

Aps_1

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG6391

Flygut - An atlas of the Drosophila adult midgut

FBgn0036111

GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents

39226

InterPro - A database of protein families, domains and functional sites

KEGG Genes - Molecular building blocks of life in the genomic space.

Dmel_CG6391

modMine - A data warehouse for the modENCODE project

FBgn0036111

Linkouts

DroID - A comprehensive database of gene and protein interactions.

FBgn0036111

DRSC - Results frm RNAi screens

FBgn0036111

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

FBgn0036111

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

CG6391-RA

FlyCyc Genes - Genes from a BioCyc PGDB for Dmel

FBGN0036111

FlyMine - An integrated database for Drosophila genomics

FBgn0036111

InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.

39226

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

Synthesis of pyrophosphates in the cytosol

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Aps

(Meltzer et al., 2019, Baranski et al., 2018, Transgenic RNAi Project members, 2017-, Nässel and Vanden Broeck, 2016, Williams et al., 2015, Japanese National Institute of Genetics, 2012.5.21, Williams et al., 2012, Winward et al., 2010)

CG6391

(Page et al., 2012, Ni et al., 2010.12.1, Winward et al., 2010, Keleman et al., 2009.8.5)

anon-WO0118547.266

Name Synonyms

Aps

Secondary FlyBase IDs

FBgn0062133

Datasets (0)

Study focus (0)

Experimental Role

Project

Project Type

Title

References (43)

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