Gene model reviewed during 5.46
Gene model reviewed during 5.56
There is only one protein coding transcript and one polypeptide associated with this gene
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\CG4328 using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\CG4328 in GBrowse 2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
dsRNA has been made from templates generated with primers directed against this gene. RNAi of CG4328 results in inappropriate anterior arborization of ddaE neurons. These neurons also show anterior or even ventral displacement of ddaD concomitant with anterior arborization of ddaE as well as displacement of ddaE arbors concomitant with misrouting of ddaD. RNAi also causes other general defects in dendrite morphogenesis.
S2 cells treated with dsRNA generated against this gene show reduced phagocytosis of Candida albicans compared to untreated cells.
RNAi generated by PCR using primers directed to this gene causes a cell growth and viability phenotype when assayed in Kc167 and S2R+ cells.