FlyBase Gene Report: Dmel\eIF3a

General Information

Symbol

Dmel\eIF3a

Species

D. melanogaster

Name

eukaryotic translation initiation factor 3 subunit a

Annotation Symbol

CG9805

Feature Type

protein_coding_gene

FlyBase ID

FBgn0037249

Gene Model Status

Current

Stock Availability

9 publicly available

Gene Summary

RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (UniProt, Q9VN25)

Contribute a Gene Snapshot for this gene.

All Summaries

Alliance
Auto summary
Gene Group
UniProtKB
Interactive Fly

Also Known As

eIF3-S10, eIF3

Key Links

Genomic Location

Cytogenetic map

82B1-82B1

Sequence location

3R:4,429,798..4,433,895 [-]

Recombination map

3-47.1

RefSeq locus

NT_033777 REGION:4429798..4433895

Sequence

Get Decorated FASTA

Genomic Maps

JBrowse

Other Genome Views

The following external sites may use different assemblies or annotations than FlyBase.

Function

Gene Ontology (GO) Annotations (11 terms)

Molecular Function (2 terms)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (2 terms)

CV Term

Evidence

References

enables mRNA binding

inferred from biological aspect of ancestor with PANTHER:PTN000360893

(GO Reference Genome Project, 2011-)

contributes_to translation initiation factor activity

inferred from biological aspect of ancestor with PANTHER:PTN000360893

(GO Reference Genome Project, 2011-)

enables translation initiation factor activity

inferred from sequence or structural similarity

(Lasko, 2000)

inferred from sequence or structural similarity with UniProtKB:Q7K550

(Gene Ontology Curators, 2002-)

Biological Process (4 terms)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (4 terms)

CV Term

Evidence

References

involved_in formation of cytoplasmic translation initiation complex

inferred from biological aspect of ancestor with PANTHER:PTN000360893

(GO Reference Genome Project, 2011-)

involved_in regulation of translational initiation

inferred from sequence or structural similarity with UniProtKB:Q7K550

(Gene Ontology Curators, 2002-)

involved_in translation reinitiation

inferred from biological aspect of ancestor with PANTHER:PTN000360893

(GO Reference Genome Project, 2011-)

involved_in translational initiation

inferred from sequence or structural similarity

(Lasko, 2000)

Cellular Component (5 terms)

Terms Based on Experimental Evidence (1 term)

CV Term

Evidence

References

located_in cytosol

inferred from high throughput direct assay

(Lye et al., 2014)

Terms Based on Predictions or Assertions (5 terms)

CV Term

Evidence

References

located_in cytosol

inferred from sequence or structural similarity

(Lasko, 2000)

part_of eukaryotic translation initiation factor 3 complex, eIF3e

inferred from biological aspect of ancestor with PANTHER:PTN000360893

(GO Reference Genome Project, 2011-)

part_of eukaryotic translation initiation factor 3 complex, eIF3m

inferred from biological aspect of ancestor with PANTHER:PTN000360893

(GO Reference Genome Project, 2011-)

part_of eukaryotic translation initiation factor 3 complex

inferred from electronic annotation with InterPro:IPR027512

(InterPro Project Members, 2004-)

inferred from sequence or structural similarity

(Lasko, 2000)

inferred from sequence or structural similarity with UniProtKB:Q7K550

(Gene Ontology Curators, 2002-)

part_of multi-eIF complex

inferred from biological aspect of ancestor with PANTHER:PTN000360893

(GO Reference Genome Project, 2011-)

Gene Group (FlyBase)

CYTOPLASMIC TRANSLATION INITIATION FACTORS

Protein Family (UniProt)

Belongs to the eIF-3 subunit A family. (Q9VN25)

Protein Signatures (InterPro)

Summaries

Gene Group (FlyBase)

CYTOPLASMIC TRANSLATION INITIATION FACTORS -: Cytoplasmic (or eukaryotic) translation initiation factors function in the initiation stage of ribosome-mediated translation in the cytoplasm. (Adapted from FBrf0233552 and PMID:20094052).

Protein Function (UniProtKB)

(UniProt, Q9VN25)

Gene Model and Products

Number of Transcripts

Number of Unique Polypeptides

Please see the JBrowse view of Dmel\eIF3a for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Structure

Protein 3D structure (Predicted by AlphaFold) (AlphaFold entry Q9VN25)

If you don't see a structure in the viewer, refresh your browser.

Model Confidence:

Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Experimentally Determined Structures

Crossreferences

Comments on Gene Model

Gene model reviewed during 5.56

Low-frequency RNA-Seq exon junction(s) not annotated.

Gene model reviewed during 5.47

Gene model reviewed during 5.57

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Assoc. CDS (aa)

eIF3a-RA

FBtr0078944

NM_141213

3773

1140

eIF3a-RD

FBtr0346646

NM_168999

3892

1140

Additional Transcript Data and Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

UniProt

RefSeq ID

GenBank

eIF3a-PA

FBpp0078584

133.9

1140

9.47

FBpp0312226

133.9

1140

9.47

Q9VN25

NP_730838

AAN13317

Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

1140 aa isoforms: eIF3a-PA, eIF3a-PD

Additional Polypeptide Data and Comments

Reported size (kDa)

Comments

External Data

Subunit Structure (UniProtKB)

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex (By similarity) (PubMed:17392269). The eIF-3 complex interacts with pix (By similarity) (PubMed:17392269).

(UniProt, Q9VN25)

Crossreferences

InterPro - A database of protein families, domains and functional sites

Linkouts

Sequences Consistent with the Gene Model

Nucleotide / Polypeptide Records

UniProt

Q9VN25

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\eIF3a using the Feature Mapper tool.

External Data

Crossreferences

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

eIF3-S10_1

Linkouts

Expression Data

Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

0.57

Transcript Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

mass spectroscopy

Stage

Tissue/Position (including subcellular localization)

Reference

adult stage

adult head

• membrane

(Aradska et al., 2015)

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Evidence

References

located_in cytosol

inferred from high throughput direct assay

(Lye et al., 2014)

Expression Deduced from Reporters

Reporter: PBac{602.P.SVS-1}eIF3a^CPTI000076

Stage

Tissue/Position (including subcellular localization)

Reference

adult stage

adult brain cell body rind

(Knowles-Barley, 2011.8.24)

High-Throughput Expression Data

Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\eIF3a in JBrowse

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\eIF3a

View exonic expression by tissue for Dmel\eIF3a

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

40563/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0037249

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0037249

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0037249

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG9805

Flygut - An atlas of the Drosophila adult midgut

FBgn0037249

Images

FlyBase Wiki

Image Based Resources

Alleles, Insertions, Transgenic Constructs, and Aberrations

Classical and Insertion Alleles ( 5 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 8 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of eIF3a

Transgenic constructs containing regulatory region of eIF3a

Aberrations (Deficiencies and Duplications) ( 5 )

Inferred from experimentation ( 5 )

Gene disrupted in

Df(3R)BSC246

(Marygold et al., 2007, Gresens and Cook, 2006.12.5)

Df(3R)ED5046

(Marygold et al., 2007)

Df(3R)ED5071

(Marygold et al., 2007)

Df(3R)ED5092

(Marygold et al., 2007)

Df(3R)ED5100

(Marygold et al., 2007)

Inferred from location ( 8 )

Variants

Variant Molecular Consequences

Alleles Representing Disease-Implicated Variants

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

lethal

eIF3a^CB05493

lethal, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

eIF3a^GD12569

lethal, with Scer\GAL4^pnr-MD237

eIF3a^GD12569

lethal, with Scer\GAL4^tin.CΔ4

eIF3a^GD12569

lethal - all die during embryonic stage, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

eIF3a^GD12569

lethal - all die during larval stage, with Scer\GAL4^Mef2.PR

eIF3a^GD12569

Sterility

Allele

female fertile, with Scer\GAL4^nanos.PG

eIF3a^JF02719

female sterile, with Scer\GAL4^nanos.PG

eIF3a^GD12569

Other Phenotypes

Allele

increased cell number | spermatogenesis, with Scer\GAL4^tj.PU

eIF3a^GD12569

Phenotype manifest in

Allele

cyst progenitor cell | ectopic, with Scer\GAL4^tj.PU

eIF3a^GD12569

Orthologs

Downloads

Download All DIOPT Orthologs

Human Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Homo sapiens (Human) (1)

Hsap\EIF3A

13 of 14

Yes

Model Organism Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Rattus norvegicus (Norway rat) (1)

Rnor\Eif3a

13 of 14

Yes

Mus musculus (laboratory mouse) (1)

Mmus\Eif3a

13 of 14

Yes

Xenopus tropicalis (Western clawed frog) (3)

Xtro\eif3a

10 of 13

Yes

Xtro\kdm4a

9 of 13

Yes

Xtro\LOC101730340

1 of 13

Yes

Danio rerio (Zebrafish) (1)

Drer\eif3s10

13 of 14

Yes

Caenorhabditis elegans (Nematode, roundworm) (1)

Cele\egl-45

13 of 14

Yes

Anopheles gambiae (African malaria mosquito) (1)

Agam\EIF3A_ANOGA

11 of 12

Yes

Arabidopsis thaliana (thale-cress) (2)

Atha\EIF3A

12 of 13

Yes

Atha\AT4G23330

1 of 13

Yes

Saccharomyces cerevisiae (Brewer's yeast) (1)

Scer\RPG1

12 of 13

Yes

Schizosaccharomyces pombe (Fission yeast) (1)

Spom\tif32

12 of 12

Yes

Escherichia coli (enterobacterium) (0)

Other Organism Orthologs (via OrthoDB)

Data provided directly from OrthoDB:eIF3a. Refer to their site for version information.

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v9.1)

Gene Symbol

Score

Source

Alignment

Drosophila melanogaster (Fruit fly) (0)

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 0 )

Human Ortholog

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Allele

Disease

Interaction

References

Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

EIF3A; eukaryotic translation initiation factor 3 subunit A

13 of 14

602039

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

Interaction Browsers

View in FlyBase Interactions Browser View in MIST tool (external link)

Please see the Physical Interaction reports below for full details

protein-protein

Physical Interaction

Assay

References

eIF3a - Dsor1

anti tag coimmunoprecipitation, peptide massfingerprinting

(Friedman et al., 2011)

eIF3a - Lkb1

anti tag coimmunoprecipitation, Identification by mass spectrometry

(Vinayagam et al., 2016)

eIF3a - Pdk1

anti tag coimmunoprecipitation, Identification by mass spectrometry

(Vinayagam et al., 2016)

eIF3a - Pi3K92E

anti tag coimmunoprecipitation, Identification by mass spectrometry

(Vinayagam et al., 2016)

eIF3a - Pten

anti tag coimmunoprecipitation, Identification by mass spectrometry

(Vinayagam et al., 2016)

eIF3a - Rheb

anti tag coimmunoprecipitation, Identification by mass spectrometry

(Vinayagam et al., 2016)

eIF3a - S6kII

anti tag coimmunoprecipitation, Identification by mass spectrometry

(Vinayagam et al., 2016)

eIF3a - Tsc1

anti tag coimmunoprecipitation, Identification by mass spectrometry

(Vinayagam et al., 2016)

eIF3a - eIF3b

experimental knowledge based

(Guruharsha et al., 2011)

eIF3a - eIF3c

experimental knowledge based

(Guruharsha et al., 2011)

eIF3a - eIF3e

experimental knowledge based

(Guruharsha et al., 2011)

eIF3a - eIF3f1

experimental knowledge based

(Guruharsha et al., 2011)

eIF3a - eIF3g1

experimental knowledge based

(Guruharsha et al., 2011)

eIF3a - eIF3h

experimental knowledge based

(Guruharsha et al., 2011)

eIF3a - eIF3k

experimental knowledge based

(Guruharsha et al., 2011)

eIF3a - eIF3l

experimental knowledge based

(Guruharsha et al., 2011)

eIF3a - eIF3m

experimental knowledge based

(Guruharsha et al., 2011)

eIF3a - foxo

anti tag coimmunoprecipitation, Identification by mass spectrometry

(Vinayagam et al., 2016)

eIF3a - gig

anti tag coimmunoprecipitation, Identification by mass spectrometry

(Vinayagam et al., 2016)

eIF3a - pix

tandem affinity purification, molecular weight estimation by silver staining, Identification by mass spectrometry

(Andersen and Leevers, 2007)

eIF3a - rictor

anti tag coimmunoprecipitation, Identification by mass spectrometry

(Vinayagam et al., 2016)

eIF3a - sima

anti tag coimmunoprecipitation, Identification by mass spectrometry

(Vinayagam et al., 2016)

RNA-protein

Physical Interaction

Assay

References

eIF3a - sfl

anti tag coimmunoprecipitation, nucleic acid uv cross-linking assay, quantitative reverse transcription pcr, reverse transcription pcr

(Song et al., 2022)

Summary of Genetic Interactions

Interaction Browsers

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

External Data

Subunit Structure (UniProtKB)

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex (By similarity) (PubMed:17392269). The eIF-3 complex interacts with pix (By similarity) (PubMed:17392269).

(UniProt, Q9VN25 )

Linkouts

BioGRID - A database of protein and genetic interactions.

65782

DroID - A comprehensive database of gene and protein interactions.

FBgn0037249

MIST (protein-protein) - An integrated Molecular Interaction Database

40563

Pathways

Signaling Pathways (FlyBase)

Metabolic Pathways

FlyBase

External Links

External Data

Linkouts

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

Class of Gene

nuclear_gene

protein_coding_gene

Genomic Location and Detailed Mapping Data

Chromosome (arm)

Recombination map

3-47.1

Cytogenetic map

82B1-82B1

Sequence location

3R:4,429,798..4,433,895 [-]

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

82B1-82B1

Limits computationally determined from genome sequence between P{PZ}l(3)02733⁰²⁷³³ and P{EP}EP974

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

3-47.1

(FlyBase, 2016)

3-44.1

(Comeron et al., 2012)

Left of (cM)

Right of (cM)

Notes

Stocks and Reagents

Stocks (9)

Aberrations including deletions of this gene Aberrations including duplications of this gene

Bloomington

27565

y¹ v¹; P{TRiP.JF02719}attP2

31186

y¹ v¹; P{TRiP.JF01699}attP2

82008

y¹ sc^* v¹ sev²¹; P{TKO.GS04393}attP40

34353

y¹ sc^* v¹ sev²¹; P{TRiP.HMS01342}attP2

15728

y¹ w^67c23; P{EPgy2}eIF3a^EY04238/TM3, Sb¹ Ser¹

Kyoto

124298

w¹¹¹⁸; P{RS3}eIF3a^UM-8038-3

115007

w¹¹¹⁸; PBac{602.P.SVS-1}eIF3a^CPTI000076

NIG-Fly

HMS01342

y¹ sc^* v¹ sev²¹; P{TRiP.HMS01342}attP2

VDRC

v28140

w¹¹¹⁸; P{GD12569}v28140/TM3

Genomic Clones (16)

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (325)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced

BDGP DGC clones

RE65203

Other clones

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

FBgn0037249

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi and Array Information

Linkouts

DRSC - Results frm RNAi screens

FBgn0037249

Antibody Information

Laboratory Generated Antibodies

Commercially Available Antibodies

Cell Line Information

Publicly Available Cell Lines

Other Stable Cell Lines

Other Comments

RNAi screen using dsRNA made from templates generated with primers directed against this gene results in aberrantly short, monopolar spindles when assayed in S2 cells. This phenotype can be observed when the screen is performed with or without Cdc27 dsRNA.

(Goshima et al., 2007)

RNAi generated by PCR using primers directed to this gene causes a cell growth and viability phenotype when assayed in Kc167 and S2R⁺ cells.

(Boutros et al., 2004)

Area matching Drosophila EST AA201223 (inverted). This EST forms a 2631bp contig with ESTs AA538867, AA439491, AA390780, AA390983, AA201661, AA391700 and AA202007. Seq. sim. to Human nucleopore gene.

(Davies, 2001.3.15)

Relationship to Other Genes

Source for database merge of

Source for merge of: eIF3-S10 anon-WO0118547.261

(FlyBase, 1996-)

Additional comments

Source for merge of eIF3-S10 anon-WO0118547.261 was sequence comparison ( date:051113 ).

(FlyBase, 1996-)

Nomenclature History

Source for database identify of

Source for identity of: eIF3-S10 CG9805

(Lasko, 2000)

Source for identity of: eIF3a eIF3-S10

(Marygold et al., 2017)

Nomenclature comments

Etymology

Synonyms and Secondary IDs (11)

Reported As

Symbol Synonym

CG9805

(Vasudevan et al., 2020, Kolkhof et al., 2017, Marygold et al., 2017, Çiçek et al., 2016, Hosono et al., 2015, Fukuoh et al., 2014, Hernández et al., 2013, Schertel et al., 2013, Christis and Munro, 2012, Müller et al., 2010, Ni et al., 2010.12.1, Perkins et al., 2009, Khokhar et al., 2008, Ni et al., 2008, Goshima et al., 2007, Boutros et al., 2004, Lasko, 2000)

EIF3-S10

(Davis et al., 2011)

EIF3A

(Malik et al., 2023)

MMAP140

(Sisson et al., 2000)

anon-WO0118547.261

eIF3

(Rui, 2024, Furusawa and Emoto, 2021)

eIF3 S10

(Thackray et al., 2020)

eIF3-s10

(Guest et al., 2011)

eIF3a

(Majane et al., 2022, Song et al., 2022, Goodman et al., 2019, Marygold et al., 2017, Transgenic RNAi Project members, 2017-, Majzoub et al., 2014, Hernández et al., 2013)

Name Synonyms

eIF3-S10

(Davis et al., 2011, Somma et al., 2008)

eukaryotic translation initiation factor 3 subunit a

Secondary FlyBase IDs

FBan0009805
FBgn0062137

Datasets (0)

Study focus (0)

Experimental Role

Project

Project Type

Title

Study result (0)

Result

Result Type

Title

External Crossreferences and Linkouts ( 46 )

Sequence Crossreferences

NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

40563

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.

UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.

Q9VN25

UniProt/Swiss-Prot - Manually annotated and reviewed records of protein sequence and functional information

Q9VN25

Other crossreferences

AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.

Q9VN25

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

40563/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0037249

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0037249

FlyMine - An integrated database for Drosophila genomics

FBgn0037249

InterPro - A database of protein families, domains and functional sites

KEGG Genes - Molecular building blocks of life in the genomic space.

dme:Dmel_CG9805

MARRVEL_MODEL - MARRVEL (model organism gene)

40563

Linkouts

BioGRID - A database of protein and genetic interactions.

65782

Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones

FBgn0037249

DroID - A comprehensive database of gene and protein interactions.

FBgn0037249

DRSC - Results frm RNAi screens

FBgn0037249

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

eIF3-S10_1

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0037249

FlyCyc Genes - Genes from a BioCyc PGDB for Dmel

FBGN0037249

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG9805

Flygut - An atlas of the Drosophila adult midgut

FBgn0037249

FlyMet - A comprehensive tissue-specific metabolomics resource for Drosophila.

FBgn0037249

iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)

TC012303

MIST (protein-protein) - An integrated Molecular Interaction Database

40563

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

References (96)

The following external sites may use different assemblies or annotations than FlyBase.

0.57

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