DNApol-iota, DNApol-ι, drad30B
Gene model reviewed during 5.49
The catalytic core consists of fingers, palm and thumb subdomains, but the fingers and thumb subdomains are much smaller than in high-fidelity polymerases; residues from five sequence motifs of the Y-family cluster around an active site cleft that can accommodate DNA and nucleotide substrates with relaxed geometric constraints, with consequently higher rates of misincorporation and low processivity.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\PolI using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\PolI in GBrowse 2
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