raps, Rapsynoid, Rad
involved in asymmetric cell divisions and establishment of cell polarity - Prefoldin acts synergistically with Pins to regulate asymmetric division of both neuroblasts and intermediate neural progenitors
AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Gene model reviewed during 5.46
There is only one protein coding transcript and one polypeptide associated with this gene
658 (aa); 72 (kD predicted)
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\pins using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\pins in GBrowse 2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: pins raps
In raps mutants, the asymmetric divisions of neuroblasts are altered; insc protein is no longer asymmetrically localized in the dividing neuroblast and the neuroblast division produces two daughter cells of similar sizes. However, the morphologically symmetrical divisions of raps mutant neuroblasts still lead to daughter cells with different fates, as shown by differences in gene expression.
Identification: identified as a protein that binds to insc in a yeast two-hybrid screen.
Isolated using a yeast two-hybrid system.