AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Low-frequency RNA-Seq exon junction(s) not annotated.
Annotated transcripts do not represent all supported alternative splices within 5' UTR.
Gene model reviewed during 5.46
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\ago using the Feature Mapper tool.
The ventrolateral body wall muscle 12 (VLM12) expresses endogenous, nuclear ago protein.
A strong pulse of nuclear ago protein is seen in the area of the morphogenetic furrow (MF) and are subsequently refined into a restricted pattern in the first few rows of cells posterior to the MF. ago becomes restricted to a single cell nucleus that occupies an anterior location within the nascent elav-positive cluster.
GBrowse - Visual display of RNA-Seq signalsView Dmel\ago in GBrowse 2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
ago acts an antagonist of the physiological response to hypoxia. ago protein physically associates with sima protein and restricts sima protein levels in vivo. Reducing ago activity in larval muscle cells elicits enhanced branching of nearby tracheal cells in normoxia.
dsRNA has been made from templates generated with primers directed against this gene.
dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology.
Area matching Drosophila EST AA392932 (inverted).
Clones of mutant cells in the eye disc result in cell fate changes and overrepresentation of mutant cells in the eye.