PP2A-B', PP2A, B56-1, B'/PR61
Annotated transcripts do not represent all possible combinations of alternative exons and/or alternative promoters.
Annotated transcripts do not represent all supported alternative splices within 5' UTR.
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.47
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\wrd using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\wrd in GBrowse 2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: wrd PP2A-B'
FlyBase curator comment: Renamed from "PP2A-B'" to 'wrd' (based on initial characterization and naming in FBrf0193166, and supported by subsequent usage) in order to clarify that this is one of two genes encoding the PP2A-B' subunit - the other is 'wdb' (FBgn0027492).
Source for merge of PP2A-B' CG7901 was sequence comparison ( date:001125 ).
Source for merge of PP2A-B' anon-WO0118547.420 was sequence comparison ( date:051113 ).
Source for merge of PP2A-B' BcDNA:GM05554 was a shared cDNA ( date:030728 ).
RNAi generated by PCR using primers directed to this gene causes a cell growth and viability phenotype when assayed in Kc167 and S2R+ cells.
Area matching Drosophila ESTs AA802438 and AI063681 (1030bp contig).
Area matching Drosophila EST AA951147. This EST forms a 695bp EST contig with AA695598 and AA540269.
Author names gene as "well rounded" because homozygous mutant synaptic boutons display a more smoothly rounded contour than wild-type.