Gene model reviewed during 5.47
There is only one protein coding transcript and one polypeptide associated with this gene
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\prt using the Feature Mapper tool.
In the third larval instar, prt protein is expressed in one to two cell bodies per hemisegment in the ventral nerve cord. These cells project medially into the neuropil in a complex pattern. Strong expression in the adult head is confined to a subset of Kenyons cells and in the calyx, vertical and medial lobes and pedunculus. prt protein was also detected in one bilateral extrinsic neuron that projects to the vertical and medial lobes of the mushroom bodies. In the adult, prt protein is expressed in all of the lobes of the mushroom bodies and calyx. Expression in the pedunculus is not uniform, showing weak labelling in the core. Apart from the mushroom bodies, prt protein is detected in 56 cell bodies in the brain. These include cells near the mushroom bodies, two to three cells in the subesophageal ganglion which project medially towards the esophogeal foramen, in the central body (fan-shaped and ellipsoid bodies) and two bilaterally symmetric clusters of two to three cells near the medial aspect of the optic lobe which project toward the medulla. In the thoracico-abdominal ganglion, prt protein is detected in three clusters of two to four cells each are found near the ventral midline.
GBrowse - Visual display of RNA-Seq signalsView Dmel\prt in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: prt CG10251
The gene is named "portabella" in light of its expression in the mushroom body and is proposed transport function.