Stage-specific extension of 3' UTRs observed during embryogenesis (FBrf0215804); all variants may not be annotated.
Gene model reviewed during 5.40
Annotated transcripts do not represent all possible combinations of alternative exons and/or alternative promoters.
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.46
A non-AUG start codon may be used for translation of one or more transcripts of this gene; based on the presence of conserved protein signatures within the 5' UTR without an in-frame AUG (FBrf0243886).
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\shep using the Feature Mapper tool.
shep protein is enriched in the embryonic CNS including the brain and ventral nerve cord, areas that are also positive for the neuron-specific protein elav. The overlap between shep and elav is partial in that shep is also expressed in glial cells. shep levels are low but detectable in non-CNS tissues
GBrowse - Visual display of RNA-Seq signalsView Dmel\shep in GBrowse 2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for merge of: CG32423 anon- EST:Posey83
Source for merge of: CG32423 BcDNA:RH63980
Source for merge of: CG10668 CG10649 CG10647
Source for merge of: CG32423 anon-WO0118547.198 anon-WO0172774.41
Source for merge of: CG32423 BcDNA:LD40028
Annotations CG10668, CG10649 and CG10647 merged as CG32423 in release 3 of the genome annotation.
Source for merge of CG32423 BcDNA:RH63980 was a shared cDNA ( date:030728 ).
Source for merge of CG32423 anon-WO0118547.198 anon-WO0172774.41 was sequence comparison ( date:051113 ).
Source for merge of CG32423 BcDNA:LD40028 was a shared cDNA ( date:030728 ).
Identified as a candidate gene for hypoxia-specific selection (via an experimental evolution paradigm) that is also differentially expressed between control and hypoxia-adapted larvae.
Nonsense-mediated mRNA decay (NMD) down-regulates a distinct splice isoform(s) of this gene.
Area matching Drosophila EST AA949873.