FlyBase Gene Report: Dmel\Rim

General Information

Symbol

Dmel\Rim

Species

D. melanogaster

Name

Rab3 interacting molecule

Annotation Symbol

CG33547

Feature Type

protein_coding_gene

FlyBase ID

FBgn0053547

Gene Model Status

Current

Stock Availability

46 publicly available

Gene Summary

Rab3 interacting molecule (Rim) encodes a scaffolding protein at the synaptic active zone, with important roles in promoting neurotransmitter release. [Date last reviewed: 2018-11-15] (FlyBase Gene Snapshot)

All Summaries

Gene Snapshot
Alliance
Auto summary
Interactive Fly

Key Links

Genomic Location

Cytogenetic map

90C8-90C10

Sequence location

3R:17,872,748..17,916,578 [-]

Recombination map

3-61

RefSeq locus

NT_033777 REGION:17872748..17916578

Sequence

Get Decorated FASTA

Genomic Maps

JBrowse

Other Genome Views

The following external sites may use different assemblies or annotations than FlyBase.

Function

Gene Ontology (GO) Annotations (18 terms)

Molecular Function (2 terms)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (2 terms)

CV Term

Evidence

References

enables small GTPase binding

inferred from electronic annotation with InterPro:IPR010911, InterPro:IPR039032

(InterPro Project Members, 2004-)

inferred from electronic annotation with InterPro:IPR039032

(InterPro Project Members, 2004-)

enables structural constituent of presynaptic active zone

inferred from biological aspect of ancestor with PANTHER:PTN000255280

(GO Reference Genome Project, 2011-)

traceable author statement

(Lützkendorf et al., 2025)

Biological Process (11 terms)

Terms Based on Experimental Evidence (3 terms)

CV Term

Evidence

References

involved_in clustering of voltage-gated calcium channels

inferred from mutant phenotype

(Graf et al., 2012)

involved_in neuromuscular synaptic transmission

inferred from mutant phenotype

(Graf et al., 2012)

involved_in regulation of synaptic plasticity

inferred from mutant phenotype

(Muller et al., 2012)

Terms Based on Predictions or Assertions (8 terms)

CV Term

Evidence

References

involved_in calcium-ion regulated exocytosis

inferred from sequence or structural similarity with UniProtKB:Q9JIR3

(Gene Ontology Curators, 2002-)

involved_in exocytosis

inferred from electronic annotation with InterPro:IPR039032

(InterPro Project Members, 2004-)

involved_in intracellular protein transport

inferred from electronic annotation with InterPro:IPR010911

(InterPro Project Members, 2004-)

involved_in presynaptic active zone assembly

traceable author statement

(Lützkendorf et al., 2025)

involved_in regulation of synaptic vesicle exocytosis

inferred from biological aspect of ancestor with PANTHER:PTN000255280

(GO Reference Genome Project, 2011-)

involved_in synaptic vesicle docking

inferred from biological aspect of ancestor with PANTHER:PTN000255280

(GO Reference Genome Project, 2011-)

involved_in synaptic vesicle exocytosis

inferred from sequence or structural similarity

(Littleton, 2000)

involved_in synaptic vesicle priming

inferred from biological aspect of ancestor with PANTHER:PTN000255280

(GO Reference Genome Project, 2011-)

Cellular Component (5 terms)

Terms Based on Experimental Evidence (2 terms)

CV Term

Evidence

References

located_in cytoskeleton of presynaptic active zone

inferred from direct assay

(Bruckner et al., 2017)

is_active_in presynaptic active zone

inferred from direct assay

(Lützkendorf et al., 2025)

located_in presynaptic active zone

inferred from direct assay

(Graf et al., 2012)

Terms Based on Predictions or Assertions (3 terms)

CV Term

Evidence

References

located_in membrane

inferred from electronic annotation with InterPro:IPR039032

(InterPro Project Members, 2004-)

is_active_in presynaptic active zone cytoplasmic component

inferred from biological aspect of ancestor with PANTHER:PTN000255280

(GO Reference Genome Project, 2011-)

is_active_in presynaptic membrane

inferred from biological aspect of ancestor with PANTHER:PTN000255280

(GO Reference Genome Project, 2011-)

Gene Group (FlyBase)

Protein Family (UniProt)

Protein Signatures (InterPro)

Summaries

Gene Snapshot

Rab3 interacting molecule (Rim) encodes a scaffolding protein at the synaptic active zone, with important roles in promoting neurotransmitter release. [Date last reviewed: 2018-11-15]

Summary (Interactive Fly)

evolutionarily conserved scaffolding protein - located at presynaptic active zones - presynaptic homeostasis - plays a critical role for the active zone cytomatrix as a substrate for synaptic plasticity

Interactive Fly

Gene Model and Products

Number of Transcripts

Number of Unique Polypeptides

Please see the JBrowse view of Dmel\Rim for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Structure

Protein 3D structure (Predicted by AlphaFold) (AlphaFold entry A0A0B4K6M2)

If you don't see a structure in the viewer, refresh your browser.

Model Confidence:

Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Experimentally Determined Structures

Crossreferences

Comments on Gene Model

Gene model reviewed during 5.39

Annotated transcripts do not represent all possible combinations of alternative exons and/or alternative promoters.

Low-frequency RNA-Seq exon junction(s) not annotated.

Gene model reviewed during 5.48

Tissue-specific extension of 3' UTRs observed during later stages (FBrf0218523, FBrf0219848); all variants may not be annotated

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Assoc. CDS (aa)

Rim-RAA

FBtr0336723

NM_001275758

6145

1358

Rim-RF

FBtr0305016

NM_001260234

11128

2798

Rim-RK

FBtr0305021

NM_001260239

11676

2798

Rim-RP

FBtr0308498

NM_001260231

10557

2792

Rim-RQ

FBtr0336713

NM_001014630

7864

1931

Rim-RR

FBtr0336714

NM_001260238

10187

1941

Rim-RS

FBtr0336715

NM_001260243

6268

1399

Rim-RT

FBtr0336716

NM_001260233

6964

1631

Rim-RU

FBtr0336717

NM_001260237

10892

1955

Rim-RV

FBtr0336718

NM_001260241

8629

1965

Rim-RW

FBtr0336719

NM_001260240

10519

2595

Rim-RX

FBtr0336720

NM_001260232

8599

1955

Rim-RY

FBtr0336721

NM_001260235

6934

1621

Rim-RZ

FBtr0336722

NM_001260242

7699

1655

Additional Transcript Data and Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

UniProt

RefSeq ID

GenBank

Rim-PAA

FBpp0307704

146.8

1358

9.73

FBpp0293553

299.6

2798

8.40

FBpp0293558

299.6

2798

8.40

FBpp0300750

299.1

2792

8.20

FBpp0307694

207.3

1931

9.24

FBpp0307695

207.7

1941

9.38

FBpp0307696

151.6

1399

9.87

FBpp0307697

175.8

1631

9.26

FBpp0307698

209.8

1955

9.29

FBpp0307699

210.1

1965

9.42

FBpp0307700

278.1

2595

8.68

FBpp0307701

209.8

1955

9.29

FBpp0307702

175.5

1621

9.09

FBpp0307703

178.3

1655

9.31

A0A0B4K6B7

NP_001247171

AFH06489

Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

1955 aa isoforms: Rim-PU, Rim-PX

2798 aa isoforms: Rim-PF, Rim-PK

Additional Polypeptide Data and Comments

Reported size (kDa)

Comments

External Data

Crossreferences

InterPro - A database of protein families, domains and functional sites

Linkouts

Sequences Consistent with the Gene Model

Nucleotide / Polypeptide Records

UniProt

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Rim using the Feature Mapper tool.

External Data

Crossreferences

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

Rim_1

Linkouts

Expression Data

Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

-0.76

Transcript Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

mass spectroscopy

Stage

Tissue/Position (including subcellular localization)

Reference

adult stage

adult head

• membrane

(Aradska et al., 2015)

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Evidence

References

located_in cytoskeleton of presynaptic active zone

inferred from direct assay

(Bruckner et al., 2017)

is_active_in presynaptic active zone

inferred from direct assay

(Lützkendorf et al., 2025)

located_in presynaptic active zone

inferred from direct assay

(Graf et al., 2012)

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\Rim in JBrowse

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\Rim

View exonic expression by tissue for Dmel\Rim

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0053547

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

42150/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0053547

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0053547

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0053547

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

Flygut - An atlas of the Drosophila adult midgut

FBgn0053547

Images

FlyBase Wiki

Image Based Resources

Alleles, Insertions, Transgenic Constructs, and Aberrations

Classical and Insertion Alleles ( 26 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 13 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of Rim

Transgenic constructs containing regulatory region of Rim

Aberrations (Deficiencies and Duplications) ( 2 )

Inferred from experimentation ( 2 )

Gene duplicated in

Dp(3;3)cpo^3.20

(Schmidt et al., 2008)

Gene disrupted in

Df(3R)cpo^3.42

(Schmidt et al., 2008)

Inferred from location ( 9 )

Variants

Variant Molecular Consequences

Alleles Representing Disease-Implicated Variants

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

viable

viable, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

Rim^GD15273

viable, with Scer\GAL4^Mef2.PR

Rim^GD15273

viable, with Scer\GAL4^pnr-MD237

Rim^GD15273

viable, with Scer\GAL4^tin.CΔ4

Rim^GD15273

viable (with Df(3R)ED5785)

Sterility

Allele

fertile

fertile (with Df(3R)ED5785)

Other Phenotypes

Allele

abnormal developmental rate | larval stage, with Scer\GAL4^phtm.PO

Rim^GD15653

abnormal neurophysiology | larval stage

Rim^V5-Znf

abnormal neurophysiology | third instar larval stage

abnormal neurophysiology | third instar larval stage, with Dcr-2^UAS.cDa, Scer\GAL4^elav-C155

Rim^GD15273

abnormal neurophysiology | third instar larval stage (with Df(3R)BSC650)

Rim^C165

abnormal neurophysiology | third instar larval stage (with Df(3R)ED5785)

Rim^Ex73

abnormal neurophysiology | third instar larval stage (with Rim¹⁰³)

Rim^Ex73

abnormal neurophysiology | third instar larval stage (with Rim^Ex73)

Rim¹⁰³

some die during larval stage, with Scer\GAL4^phtm.PO

Rim^GD15653

Phenotype manifest in

Allele

embryonic/larval neuromuscular junction | larval stage

Rim^V5-Znf

embryonic/larval neuromuscular junction | third instar larval stage (with Rim¹⁰³)

Rim^Ex73

embryonic/larval neuromuscular junction | third instar larval stage (with Rim^Ex73)

Rim¹⁰³

Orthologs

Downloads

Download All DIOPT Orthologs

Human Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Homo sapiens (Human) (27)

Hsap\RIMS1

11 of 14

Yes

Hsap\RIMS2

11 of 14

Yes

Hsap\RIMS3

7 of 14

Yes

Hsap\RIMS4

7 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Model Organism Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Rattus norvegicus (Norway rat) (13)

Rnor\Rims1

11 of 14

Yes

Rnor\Rims2

11 of 14

Yes

Rnor\Rims3

7 of 14

Yes

Rnor\Rims4

7 of 14

Yes

Rnor\Pclo

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Mus musculus (laboratory mouse) (14)

Mmus\Rims2

11 of 14

Yes

Mmus\Rims1

10 of 14

Yes

Mmus\Rims3

7 of 14

Yes

Mmus\Rims4

7 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Xenopus tropicalis (Western clawed frog) (25)

Xtro\rims1

7 of 13

Yes

Xtro\rims2

6 of 13

Yes

Xtro\acmsd

5 of 13

Yes

Xtro\rims3

4 of 13

Yes

Xtro\rims4

4 of 13

Yes

Xtro\cep97

2 of 13

Xtro\c10orf71

1 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Danio rerio (Zebrafish) (23)

Drer\rims1b

11 of 14

Yes

Drer\rims1a

10 of 14

Yes

Drer\rims3

7 of 14

Yes

Drer\rims4

7 of 14

Yes

Drer\rims2a

6 of 14

Yes

Drer\rims2b

6 of 14

Yes

Drer\doc2b

1 of 14

Drer\LOC100537874

1 of 14

Yes

Drer\pcloa

1 of 14

Drer\pclob

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Caenorhabditis elegans (Nematode, roundworm) (6)

Cele\unc-10

11 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Anopheles gambiae (African malaria mosquito) (6)

Agam\AgaP_AGAP001690

9 of 12

Yes

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

Arabidopsis thaliana (thale-cress) (0)

Saccharomyces cerevisiae (Brewer's yeast) (0)

Schizosaccharomyces pombe (Fission yeast) (0)

Escherichia coli (enterobacterium) (0)

Other Organism Orthologs (via OrthoDB)

Data provided directly from OrthoDB:Rim. Refer to their site for version information.

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v9.1)

Gene Symbol

Score

Source

Alignment

Drosophila melanogaster (Fruit fly) (9)

2 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Rph

1 of 13

Syt1

1 of 13

Sytα

1 of 13

Sytβ

1 of 13

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 5 )

Allele

Disease

Evidence

References

Rim^Ex98

model of schizophrenia

CEA

(Hidalgo et al., 2021)

Rim¹⁰³

model of autism spectrum disorder

CEA

(Genç et al., 2020)

Rim^MI03470

model of schizophrenia

CEA

(Hidalgo et al., 2021)

Rim^JF02610

model of schizophrenia

CEA

(Hidalgo et al., 2021)

Rim^HMC02936

model of schizophrenia

CEA

(Hidalgo et al., 2021)

Potential Models Based on Orthology ( 0 )

Human Ortholog

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Allele

Disease

Interaction

References

Rim¹⁰³

exacerbates autism spectrum disorder

modeled by kis¹

(Genç et al., 2020)

modeled by Chd1¹

(Genç et al., 2020)

model of autism spectrum disorder

is exacerbated by Pdk1³³

(Genç et al., 2020)

is exacerbated by wrd¹⁰⁴

(Genç et al., 2020)

Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

RIMS1; regulating synaptic membrane exocytosis 1

11 of 14

606629

RIMS2; regulating synaptic membrane exocytosis 2

11 of 14

606630

CONE-ROD SYNAPTIC DISORDER SYNDROME, CONGENITAL NONPROGRESSIVE; CRSDS

RIMS3; regulating synaptic membrane exocytosis 3

7 of 14

611600

RIMS4; regulating synaptic membrane exocytosis 4

7 of 14

611601

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

Interaction Browsers

View in FlyBase Interactions Browser View in MIST tool (external link)

Please see the Physical Interaction reports below for full details

protein-protein

Physical Interaction

Assay

References

Rim - Fife

anti tag coimmunoprecipitation, anti tag western blot

(Bruckner et al., 2017)

Rim - Liprin-α

anti tag coimmunoprecipitation, peptide massfingerprinting

(Li et al., 2014)

Rim - Rbp

two hybrid, isothermal titration calorimetry, predetermined participant

(Petzoldt et al., 2020, Siebert et al., 2015, Liu et al., 2011)

Summary of Genetic Interactions

Interaction Browsers

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

External Data

Linkouts

DroID - A comprehensive database of gene and protein interactions.

FBgn0053547

MIST (protein-protein) - An integrated Molecular Interaction Database

42150

Pathways

Signaling Pathways (FlyBase)

Metabolic Pathways

FlyBase

External Links

External Data

Linkouts

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

SignaLink - A signaling pathway resource with multi-layered regulatory networks.

Q9VEE5

Class of Gene

gene_with_edited_transcript

(Rodriguez et al., 2012, Graveley et al., 2011)

nuclear_gene

protein_coding_gene

Genomic Location and Detailed Mapping Data

Chromosome (arm)

Recombination map

3-61

Cytogenetic map

90C8-90C10

Sequence location

3R:17,872,748..17,916,578 [-]

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

90C8-90C10

; Limits computationally determined from genome sequence between P{PZ}l(3)07882⁰⁷⁸⁸² and P{EP}cpo^EP3679

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

90C-90D

(Lloyd et al., 2000)

Determined by comparing Celera genomic sequence with sequence from BDGP BAC and P1 clones.

(Lloyd et al., 2000)

Experimentally Determined Recombination Data

Location

3-61

(FlyBase, 2016)

3-60.4

(Comeron et al., 2012)

Left of (cM)

Right of (cM)

Notes

Stocks and Reagents

Stocks (46)

Aberrations including deletions of this gene Aberrations including duplications of this gene

Bloomington

78050

w^*; P{UAS-Rim.G}3

Korea

12479

P{VT043365-GAL4}attP2

12480

P{VT043378-GAL4}attP2

12972

P{VT043361-GAL4}attP2

13191

P{VT043372-GAL4}attP2

15238

P{VT043368-GAL4}attP2

15239

P{VT043377-GAL4}attP2

14545

P{VT043361-lexA}attP2

11096

7305R-1

7321R-1

7321R-3

More stocks available...

Genomic Clones (30)

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (9)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced

BDGP DGC clones

Other clones

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

FBgn0053547

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi and Array Information

Linkouts

DRSC - Results frm RNAi screens

FBgn0053547

Antibody Information

Laboratory Generated Antibodies

Commercially Available Antibodies

Cell Line Information

Publicly Available Cell Lines

Other Stable Cell Lines

Other Comments

Rim promotes the accumulation of Ca[2+] channels and synaptic vesicles in the readily releasable pool at release sites of the active zone.

(Graf et al., 2012)

RNAi generated by PCR using primers directed to CG7305 causes a cell growth and viability phenotype when assayed in Kc167 and S2R⁺ cells.

(Boutros et al., 2004)

dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R⁺ cell morphology.

(Kiger et al., 2003)

Relationship to Other Genes

Source for database merge of

Source for merge of: Rim CG7301 CG7305

(FlyBase Genome Annotators, 2005)

Additional comments

Annotations CG7301, CG7305 and CG7321 merged as CG33547 (which corresponds to Rim) in release 4.1 of the genome annotation.

(FlyBase Genome Annotators, 2005)

Nomenclature History

Source for database identify of

Source for identity of: Rim CG7321

(Verstreken and Bellen, 2000.9.4)

Nomenclature comments

Etymology

Synonyms and Secondary IDs (14)

Reported As

Symbol Synonym

CG33547

(Meadows, 2014.12.12, Ellis and Carney, 2011, Ni et al., 2010.12.1)

CG7301

(Wang and Sudhof, 2003)

CG7305

(Boutros et al., 2004)

CG7321

(Wang and Sudhof, 2003, Whitfield et al., 2002, Adolfsen and Littleton, 2001)

DRIM

(Liu et al., 2011)

DmRIM

(Bruckner et al., 2012)

RIM

(Sauvola and Littleton, 2021, Frank et al., 2020, Wentzel et al., 2018, Bruckner et al., 2017, Muller et al., 2015, Siebert et al., 2015, Yamanaka et al., 2015, Frank, 2014, Li et al., 2014, Graf et al., 2012, Lloyd et al., 2000)

UNC-10/RIM

(Zhen and Jin, 2004)

dm-Rim

(Fukuda, 2004)

rim

(Ghelani et al., 2023, Mrestani et al., 2023, Paul et al., 2022, Goel and Dickman, 2021, Nair et al., 2021, Chou et al., 2020, Petzoldt et al., 2020, Hauswirth et al., 2018, Orr et al., 2017, Davis and Müller, 2015, Gaviño et al., 2015, Harris et al., 2015)

rim-1

(Scholz et al., 2019)

Name Synonyms

Rab3 interacting molecule

(Graf et al., 2012)

Rab3-interacting molecule

(Davis and Müller, 2015)

Rim

Secondary FlyBase IDs

FBgn0038556
FBgn0038557
FBgn0038559
FBtr0083520
FBpp0082944
FBtr0083521
FBpp0082945

Datasets (0)

Study focus (0)

Experimental Role

Project

Project Type

Title

Study result (0)

Result

Result Type

Title

External Crossreferences and Linkouts ( 107 )

Sequence Crossreferences

NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

42150

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.

UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.

A0A0B4K6M2

UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information

Other crossreferences

AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.

A0A0B4K6M2

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0053547

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

42150/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0053547

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0053547

FlyMine - An integrated database for Drosophila genomics

FBgn0053547

InterPro - A database of protein families, domains and functional sites

KEGG Genes - Molecular building blocks of life in the genomic space.

dme:Dmel_CG33547

MARRVEL_MODEL - MARRVEL (model organism gene)

42150

Linkouts

Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones

FBgn0053547

DroID - A comprehensive database of gene and protein interactions.

FBgn0053547

DRSC - Results frm RNAi screens

FBgn0053547

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

Rim_1

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0053547

FlyCyc Genes - Genes from a BioCyc PGDB for Dmel

FBGN0053547

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

Flygut - An atlas of the Drosophila adult midgut

FBgn0053547

iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)

TC014424

Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution

Interactive Fly

MIST (protein-protein) - An integrated Molecular Interaction Database

42150

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

SignaLink - A signaling pathway resource with multi-layered regulatory networks.

Q9VEE5

References (103)

The following external sites may use different assemblies or annotations than FlyBase.

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