Open Close
General Information
Symbol
Dmel\Mer
Species
D. melanogaster
Name
Merlin
Annotation Symbol
CG14228
Feature Type
FlyBase ID
FBgn0086384
Gene Model Status
Stock Availability
Gene Summary
Merlin (Mer) encodes a FERM domain containing protein that promotes assembly of a functional Hippo signaling complex at the apical cell cortex. It has also been associated with cell junctions and endocytic compartments. [Date last reviewed: 2019-02-28] (FlyBase Gene Snapshot)
Also Known As

Dmerlin, BG01543, D-Mer

Key Links
Genomic Location
Cytogenetic map
Sequence location
X:19,689,697..19,693,500 [-]
Recombination map
1-64
RefSeq locus
NC_004354 REGION:19689697..19693500
Sequence
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
Function
GO Summary Ribbons
Gene Ontology (GO) Annotations (44 terms)
Molecular Function (2 terms)
Terms Based on Experimental Evidence (1 term)
CV Term
Evidence
References
inferred from physical interaction with FLYBASE:arm; FB:FBgn0000117
inferred from physical interaction with FLYBASE:Moe; FB:FBgn0011661
inferred from physical interaction with FLYBASE:ex; FB:FBgn0004583
inferred from physical interaction with UniProtKB:Q9VFG8
(assigned by UniProt )
Terms Based on Predictions or Assertions (1 term)
CV Term
Evidence
References
inferred from electronic annotation with InterPro:IPR008954
(assigned by InterPro )
Biological Process (27 terms)
Terms Based on Experimental Evidence (27 terms)
CV Term
Evidence
References
involved_in axis specification
inferred from mutant phenotype
inferred from expression pattern
inferred from genetic interaction with FLYBASE:crb; FB:FBgn0259685
inferred from genetic interaction with FLYBASE:ex; FB:FBgn0004583
involved_in endocytosis
inferred from expression pattern
inferred from mutant phenotype
involved_in hippo signaling
inferred from mutant phenotype
(assigned by UniProt )
inferred from mutant phenotype
inferred from mutant phenotype
inferred from mutant phenotype
inferred from genetic interaction with FLYBASE:ex; FB:FBgn0004583
inferred from mutant phenotype
inferred from genetic interaction with FLYBASE:ft; FB:FBgn0001075
inferred from genetic interaction with FLYBASE:l(2)gl; FB:FBgn0002121
inferred from direct assay
inferred from mutant phenotype
inferred from mutant phenotype
inferred from genetic interaction with FLYBASE:ex; FB:FBgn0004583
inferred from expression pattern
inferred from mutant phenotype
inferred from genetic interaction with FLYBASE:ex; FB:FBgn0004583
inferred from mutant phenotype
involved_in spermatogenesis
inferred from mutant phenotype
Terms Based on Predictions or Assertions (0 terms)
Cellular Component (15 terms)
Terms Based on Experimental Evidence (14 terms)
CV Term
Evidence
References
inferred from direct assay
(assigned by UniProt )
inferred from direct assay
inferred from direct assay
inferred from direct assay
located_in cell cortex
inferred from direct assay
colocalizes_with cell-cell junction
inferred from direct assay
inferred from direct assay
(assigned by UniProt )
inferred from physical interaction with FLYBASE:ex; FB:FBgn0004583, FLYBASE:kibra; FB:FBgn0262127
located_in membrane
inferred from direct assay
located_in Nebenkern
inferred from direct assay
located_in plasma membrane
inferred from direct assay
inferred from direct assay
NOT located_in fusome
inferred from direct assay
Terms Based on Predictions or Assertions (1 term)
CV Term
Evidence
References
located_in cytoskeleton
inferred from electronic annotation with InterPro:IPR000299
(assigned by InterPro )
Gene Group (FlyBase)
Protein Family (UniProt)
-
Summaries
Gene Snapshot
Merlin (Mer) encodes a FERM domain containing protein that promotes assembly of a functional Hippo signaling complex at the apical cell cortex. It has also been associated with cell junctions and endocytic compartments. [Date last reviewed: 2019-02-28]
Pathway (FlyBase)
Positive Regulators of Hippo Signaling Pathway -
The Hippo signaling pathway is an intracellular kinase cascade in which hpo kinase in complex with sav, phosphorylates wts kinase which, in turn, phosphorylates yki transcriptional co-activator leading to its cytosolic retention. Positive regulators of the pathway, enhance the cytosolic retention of yki, negatively regulating tissue growth (Adapted from FBrf0224870).
Gene Group (FlyBase)
KIBRA-EX-MER COMPLEX -
The KEM complex is an apical protein complex that contains the proteins Kibra, Expanded and Merlin. It positively regulates the Hippo pathway, acting as a scaffolding complex. (Adapted from FBrf0210017).
Protein Function (UniProtKB)
Regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein Hippo (Hpo), in complex with its regulatory protein Salvador (Sav), phosphorylates and activates Warts (Wts) in complex with its regulatory protein Mats, which in turn phosphorylates and inactivates the Yorkie (Yki) oncoprotein. Mer acts synergistically along with Ex and Kibra to regulate the Hippo signaling pathway.
(UniProt, Q24564)
Summary (Interactive Fly)

ERM family, protein 4.1 superfamily - functions to restrain cell proliferation - a junctional component also associated with endocytosis - the spatial organization of Hippo signaling at the plasma membrane is mediated by the tumor suppressor Merlin/NF2.

Gene Model and Products
Number of Transcripts
2
Number of Unique Polypeptides
1

Please see the JBrowse view of Dmel\Mer for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)
Isoform displayed:
Pfam protein domains
InterPro name
classification
start
end
Protein Domains (via SMART)
Isoform displayed:
SMART protein domains
InterPro name
classification
start
end
Comments on Gene Model

Gene model reviewed during 5.51

Gene model reviewed during 5.56

Sequence Ontology: Class of Gene
Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Assoc. CDS (aa)
FBtr0074754
2503
635
FBtr0345992
3400
635
Additional Transcript Data and Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
RefSeq ID
GenBank
FBpp0074523
74.5
635
6.39
FBpp0311877
74.5
635
6.39
Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

635 aa isoforms: Mer-PA, Mer-PB
Additional Polypeptide Data and Comments
Reported size (kDa)
Comments
External Data
Subunit Structure (UniProtKB)

Interacts with Moe and arm at the adherens junction (PubMed:8666669). Forms a complex with Kibra and Ex (PubMed:20159598). Interacts (via FERM domain) with Sav (via FBM motif) (PubMed:20159598). Interacts with Schip1 (PubMed:26954546).

(UniProt, Q24564)
Linkouts
Sequences Consistent with the Gene Model
Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Mer using the Feature Mapper tool.

External Data
Crossreferences
Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
Linkouts
Expression Data
Expression Summary Ribbons
Colored tiles in ribbon indicate that expression data has been curated by FlyBase for that anatomical location. Colorless tiles indicate that there is no curated data for that location.
For complete stage-specific expression data, view the modENCODE Development RNA-Seq section under High-Throughput Expression below.
Transcript Expression
Additional Descriptive Data
Marker for
 
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
 
Subcellular Localization
CV Term
Evidence
References
inferred from direct assay
(assigned by UniProt )
inferred from direct assay
inferred from direct assay
inferred from direct assay
located_in cell cortex
inferred from direct assay
colocalizes_with cell-cell junction
inferred from direct assay
inferred from direct assay
(assigned by UniProt )
inferred from physical interaction with FLYBASE:ex; FB:FBgn0004583, FLYBASE:kibra; FB:FBgn0262127
located_in membrane
inferred from direct assay
located_in Nebenkern
inferred from direct assay
located_in plasma membrane
inferred from direct assay
inferred from direct assay
NOT located_in fusome
inferred from direct assay
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools

GBrowse - Visual display of RNA-Seq signals

View Dmel\Mer in GBrowse 2
RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region
Reference
See Gelbart and Emmert, 2013 for analysis details and data files for all genes.
Developmental Proteome: Life Cycle
Developmental Proteome: Embryogenesis
External Data and Images
Linkouts
BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
EMBL-EBI Single Cell Expression Atlas
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
Flygut - An atlas of the Drosophila adult midgut
Images
Alleles, Insertions, Transgenic Constructs, and Aberrations
Classical and Insertion Alleles ( 12 )
For All Classical and Insertion Alleles Show
 
Other relevant insertions
Transgenic Constructs ( 42 )
For All Alleles Carried on Transgenic Constructs Show
Transgenic constructs containing/affecting coding region of Mer
Transgenic constructs containing regulatory region of Mer
Aberrations (Deficiencies and Duplications) ( 6 )
Alleles Representing Disease-Implicated Variants
Phenotypes
For more details about a specific phenotype click on the relevant allele symbol.
Lethality
Allele
Sterility
Allele
Other Phenotypes
Allele
Phenotype manifest in
Allele
adult cuticle & head
adult cuticle & head | posterior
adult cuticle & head | ventral
egg chamber | posterior & follicle cell | somatic clone | rescuable maternal effect | cell non-autonomous
egg chamber | posterior & follicle cell | supernumerary | conditional ts
embryonic/first instar larval cuticle & abdominal segment | conditional ts
follicle cell & centrosome & egg chamber | posterior | conditional ts
follicle cell & egg chamber | posterior | conditional ts
interommatidial bristle & eye disc & pupa
nucleus & elongation stage spermatid
oocyte & pericentriolar material | conditional ts
spindle & spermatocyte
Orthologs
Human Orthologs (via DIOPT v8.0)
Homo sapiens (Human) (8)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Alignment
Complementation?
Transgene?
14 of 15
Yes
Yes
 
10  
2 of 15
No
No
1  
2 of 15
No
No
2 of 15
No
No
1 of 15
No
Yes
1 of 15
No
Yes
1 of 15
No
Yes
1 of 15
No
Yes
Model Organism Orthologs (via DIOPT v8.0)
Mus musculus (laboratory mouse) (9)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Alignment
Complementation?
Transgene?
14 of 15
Yes
Yes
2 of 15
No
No
2 of 15
No
No
1 of 15
No
Yes
1 of 15
No
Yes
1 of 15
No
Yes
1 of 15
No
No
1 of 15
No
Yes
1 of 15
No
No
Rattus norvegicus (Norway rat) (8)
11 of 13
Yes
Yes
2 of 13
No
No
2 of 13
No
No
2 of 13
No
No
1 of 13
No
Yes
1 of 13
No
Yes
1 of 13
No
No
1 of 13
No
Yes
Xenopus tropicalis (Western clawed frog) (7)
9 of 12
Yes
Yes
2 of 12
No
No
2 of 12
No
No
2 of 12
No
No
1 of 12
No
Yes
1 of 12
No
Yes
1 of 12
No
Yes
Danio rerio (Zebrafish) (13)
14 of 15
Yes
Yes
10 of 15
No
Yes
2 of 15
No
No
2 of 15
No
No
2 of 15
No
No
1 of 15
No
Yes
1 of 15
No
Yes
1 of 15
No
Yes
1 of 15
No
Yes
1 of 15
No
Yes
1 of 15
No
No
Caenorhabditis elegans (Nematode, roundworm) (3)
5 of 15
Yes
Yes
2 of 15
No
No
1 of 15
No
Yes
Arabidopsis thaliana (thale-cress) (0)
No records found.
Saccharomyces cerevisiae (Brewer's yeast) (0)
No records found.
Schizosaccharomyces pombe (Fission yeast) (1)
1 of 12
Yes
Yes
Ortholog(s) in Drosophila Species (via OrthoDB v9.1) ( EOG091904HP )
Organism
Common Name
Gene
AAA Syntenic Ortholog
Multiple Dmel Genes in this Orthologous Group
Drosophila suzukii
Spotted wing Drosophila
Drosophila simulans
Drosophila sechellia
Drosophila erecta
Drosophila yakuba
Drosophila ananassae
Drosophila pseudoobscura pseudoobscura
Drosophila persimilis
Drosophila willistoni
Drosophila virilis
Drosophila mojavensis
Drosophila grimshawi
Orthologs in non-Drosophila Dipterans (via OrthoDB v9.1) ( EOG091503QM )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Musca domestica
House fly
Glossina morsitans
Tsetse fly
Lucilia cuprina
Australian sheep blowfly
Mayetiola destructor
Hessian fly
Aedes aegypti
Yellow fever mosquito
Aedes aegypti
Yellow fever mosquito
Anopheles darlingi
American malaria mosquito
Anopheles gambiae
Malaria mosquito
Culex quinquefasciatus
Southern house mosquito
Culex quinquefasciatus
Southern house mosquito
Orthologs in non-Dipteran Insects (via OrthoDB v9.1) ( EOG090W04L5 )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Bombyx mori
Silkmoth
Danaus plexippus
Monarch butterfly
Heliconius melpomene
Postman butterfly
Apis florea
Little honeybee
Apis mellifera
Western honey bee
Bombus impatiens
Common eastern bumble bee
Bombus terrestris
Buff-tailed bumblebee
Linepithema humile
Argentine ant
Megachile rotundata
Alfalfa leafcutting bee
Nasonia vitripennis
Parasitic wasp
Dendroctonus ponderosae
Mountain pine beetle
Tribolium castaneum
Red flour beetle
Pediculus humanus
Human body louse
Rhodnius prolixus
Kissing bug
Cimex lectularius
Bed bug
Acyrthosiphon pisum
Pea aphid
Zootermopsis nevadensis
Nevada dampwood termite
Orthologs in non-Insect Arthropods (via OrthoDB v9.1) ( EOG090X04HS )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Strigamia maritima
European centipede
Stegodyphus mimosarum
African social velvet spider
Tetranychus urticae
Two-spotted spider mite
Daphnia pulex
Water flea
Orthologs in non-Arthropod Metazoa (via OrthoDB v9.1) ( EOG091G06UO )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Strongylocentrotus purpuratus
Purple sea urchin
Strongylocentrotus purpuratus
Purple sea urchin
Strongylocentrotus purpuratus
Purple sea urchin
Strongylocentrotus purpuratus
Purple sea urchin
Ciona intestinalis
Vase tunicate
Ciona intestinalis
Vase tunicate
Gallus gallus
Domestic chicken
Gallus gallus
Domestic chicken
Gallus gallus
Domestic chicken
Gallus gallus
Domestic chicken
Gallus gallus
Domestic chicken
Paralogs
Paralogs (via DIOPT v8.0)
Drosophila melanogaster (Fruit fly) (2)
4 of 10
1 of 10
Human Disease Associations
FlyBase Human Disease Model Reports
Disease Model Summary Ribbon
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 1 )
Allele
Disease
Evidence
References
Potential Models Based on Orthology ( 2 )
Human Ortholog
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 2 )
Disease Associations of Human Orthologs (via DIOPT v8.0 and OMIM)
Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
Functional Complementation Data
Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
Dmel gene
Ortholog showing functional complementation
Supporting References
Interactions
Summary of Physical Interactions
esyN Network Diagram
Show neighbor-neighbor interactions:
Select Layout:
Legend:
Protein
RNA
Selected Interactor(s)
Interactions Browser

Please see the Physical Interaction reports below for full details
protein-protein
Physical Interaction
Assay
References
Summary of Genetic Interactions
esyN Network Diagram
esyN Network Key:
Suppression
Enhancement

Please look at the allele data for full details of the genetic interactions
Starting gene(s)
Interaction type
Interacting gene(s)
Reference
Starting gene(s)
Interaction type
Interacting gene(s)
Reference
External Data
Subunit Structure (UniProtKB)
Interacts with Moe and arm at the adherens junction (PubMed:8666669). Forms a complex with Kibra and Ex (PubMed:20159598). Interacts (via FERM domain) with Sav (via FBM motif) (PubMed:20159598). Interacts with Schip1 (PubMed:26954546).
(UniProt, Q24564 )
Linkouts
BioGRID - A database of protein and genetic interactions.
DroID - A comprehensive database of gene and protein interactions.
InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.
MIST (genetic) - An integrated Molecular Interaction Database
MIST (protein-protein) - An integrated Molecular Interaction Database
Pathways
Signaling Pathways (FlyBase)
Positive Regulators of Hippo Signaling Pathway -
The Hippo signaling pathway is an intracellular kinase cascade in which hpo kinase in complex with sav, phosphorylates wts kinase which, in turn, phosphorylates yki transcriptional co-activator leading to its cytosolic retention. Positive regulators of the pathway, enhance the cytosolic retention of yki, negatively regulating tissue growth (Adapted from FBrf0224870).
Metabolic Pathways
External Data
Linkouts
KEGG Pathways - Wiring diagrams of molecular interactions, reactions and relations.
Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.
Genomic Location and Detailed Mapping Data
Chromosome (arm)
X
Recombination map
1-64
Cytogenetic map
Sequence location
X:19,689,697..19,693,500 [-]
FlyBase Computed Cytological Location
Cytogenetic map
Evidence for location
18E1-18E1
Limits computationally determined from genome sequence between P{EP}Sec61γEP1511 and P{EP}EP1116&P{EP}EP1344EP1344
Experimentally Determined Cytological Location
Cytogenetic map
Notes
References
18D-18E
(determined by in situ hybridisation)
Experimentally Determined Recombination Data
Left of (cM)
Right of (cM)
Notes
Stocks and Reagents
Stocks (13)
Genomic Clones (10)
 

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (25)
 

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced
BDGP DGC clones
Other clones
Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

cDNA Clones, End Sequenced (ESTs)
RNAi and Array Information
Linkouts
DRSC - Results frm RNAi screens
GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
Antibody Information
Laboratory Generated Antibodies
 

polyclonal

Commercially Available Antibodies
 
Other Information
Relationship to Other Genes
Source for database identify of
Source for database merge of

Source for merge of: Mer BG01543

Additional comments

The gene referred to in FlyBase as "mer" (FBgn0041733) is not the same gene as that referred to in FlyBase as "Mer" (FBgn0086384) - they are on different chromosomes.

Other Comments

dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology.

dsRNA made from templates generated with primers directed against this gene is tested in an RNAi screen for effects on actin-based lamella formation.

Mer is specifically required only in the posterior follicle cells to initiate axis formation in the oocyte. It is not required to specify posterior follicle cell identity in response to the grk signal from the oocyte, but is required for the unknown polarising signal back to the oocyte. Mer is also required non-autonomously to maintain cell polarity and limit proliferation in the posterior follicle cells (that have received the grk signal), but is not required in embryos and larvae.

Mer and ex function cooperatively in regulating cell proliferation and differentiation in developing epithelial cells.

Mer is not allelic to btdl.

Mer and Moe are frequently coexpressed in developing tissues, but their subcellular localisations are distinct. Moe shows continuous plasma membrane association and Mer is localised in punctate structures that are associated with both the plasma membrane and the cytoplasm. Mer is associated with endocytic compartments in cultured cells.

The Mer gene product is not a component of fusomes.

Origin and Etymology
Discoverer
Etymology
Identification
External Crossreferences and Linkouts ( 57 )
Sequence Crossreferences
NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.
UniProt/Swiss-Prot - Manually annotated and reviewed records of protein sequence and functional information
UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information
Other crossreferences
BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones
EMBL-EBI Single Cell Expression Atlas
Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
Flygut - An atlas of the Drosophila adult midgut
GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)
KEGG Genes - Molecular building blocks of life in the genomic space.
MARRVEL_MODEL
modMine - A data warehouse for the modENCODE project
Linkouts
BioGRID - A database of protein and genetic interactions.
DroID - A comprehensive database of gene and protein interactions.
DRSC - Results frm RNAi screens
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
FlyCyc Genes - Genes from a BioCyc PGDB for Dmel
FlyMine - An integrated database for Drosophila genomics
Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution
InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.
KEGG Pathways - Wiring diagrams of molecular interactions, reactions and relations.
MIST (genetic) - An integrated Molecular Interaction Database
MIST (protein-protein) - An integrated Molecular Interaction Database
Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.
Synonyms and Secondary IDs (15)
Reported As
Symbol Synonym
Emr2
Mer
(Cho and Jiang, 2021, Tokamov et al., 2021, Yang and Choi, 2021, Chang et al., 2019, Gokhale and Pfleger, 2019, Jiménez-Martínez et al., 2019, Snigdha et al., 2019, Xu et al., 2019, Yee et al., 2019, Bae and Luo, 2018, Camuglia et al., 2018, Elbediwy and Thompson, 2018, Fletcher et al., 2018, Fulford et al., 2018, Richardson and Portela, 2017, Su et al., 2017, Transgenic RNAi Project members, 2017-, Fallahi et al., 2016, Hu et al., 2016, Meng et al., 2016, Yadav et al., 2016, Cao et al., 2015, Doggett et al., 2015, Irvine and Harvey, 2015, Keder et al., 2015, Panneton et al., 2015, Zheng et al., 2015, Abeysundara et al., 2014, Gavilan et al., 2014, Sadeqzadeh et al., 2014, Tipping and Perrimon, 2014, Andersen et al., 2013, Deng et al., 2013, Ilanges et al., 2013, Johnston, 2013, Kwon et al., 2013, Kwon et al., 2013, Lucas et al., 2013, Matsui and Lai, 2013, Vaque et al., 2013, Wehr et al., 2013, Yin et al., 2013, Yu and Guan, 2013, Fabian and Brill, 2012, Fausti et al., 2012, Hafezi et al., 2012, Jin et al., 2012, Liu et al., 2012, Poernbacher et al., 2012, Yue et al., 2012, Bao et al., 2011, Boggiano et al., 2011, Carreira et al., 2011, Chan et al., 2011, Dubatolova et al., 2011, Fernández et al., 2011, Genevet and Tapon, 2011, Halder and Johnson, 2011, Poon et al., 2011, Reddy and Irvine, 2011, Richter et al., 2011, Salah and Aqeilan, 2011, Tiwari et al., 2011, Toku et al., 2011, Zhao et al., 2011, Baumgartner et al., 2010, Baumgartner et al., 2010, Benseñor et al., 2010, Dubatolova et al., 2010, Dubatolova et al., 2010, Genevet et al., 2010, Kopyl et al., 2010, Kopyl et al., 2010, LaJeunesse, 2010, Lebedeva et al., 2010, Lebedeva et al., 2010, Milton et al., 2010, Pirraglia et al., 2010, Popodi et al., 2010-, Reddy et al., 2010, Robinson et al., 2010, Venken et al., 2010, Yudina et al., 2010, Yu et al., 2010, Yu et al., 2010, Genevet et al., 2009, Hamaratoglu et al., 2009, Omelyanchuk et al., 2009, Mensch et al., 2008, Oh and Irvine, 2008, Willecke et al., 2008, Yudina et al., 2008, Zhao et al., 2008, Bakal et al., 2007, Hamaratoglu et al., 2007, Rasmussen and Kellis, 2007, Cho et al., 2006, Edgar, 2006, Hamaratoglu et al., 2006, Hariharan, 2006, Hughes and Fehon, 2006, Maitra et al., 2006, Maitra et al., 2006, Silva, 2006, Silva et al., 2006, Stanyon et al., 2004, Johnston and Gallant, 2002, McCartney et al., 2000, Pickeral et al., 2000)
Name Synonyms
BG01543
Ezrin-moesin-radixin-2
Merlin/Neurofibromin 2
Secondary FlyBase IDs
  • FBgn0013951
  • FBgn0070004
  • FBgn0014341
Datasets (1)
Study focus (1)
Experimental Role
Project
Project Type
Title
  • bait_protein
Interaction map generated by purification of Hippo pathway factors, with identification of copurifying proteins by mass spectrometry.
References (275)