FB2025_05 , released December 11, 2025
Gene: Dmel\drd
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General Information
Symbol
Dmel\drd
Species
D. melanogaster
Name
drop dead
Annotation Symbol
CG33968
Feature Type
protein_coding_gene
FlyBase ID
FBgn0260006
Gene Model Status
Current
Stock Availability
7 publicly available
Gene Summary
drop dead (drd) encodes an integral membrane protein required for female fertility and for proper function of the gut and respiratory tracheae. [Date last reviewed: 2019-03-07] (FlyBase Gene Snapshot)
All Summaries
Also Known As

lwf, beltless, lot's wife, blt, lots wife

Key Links
Genomic Location
Cytogenetic map
13A12-13B1
Sequence location
Recombination map
1-50
RefSeq locus
NC_004354 REGION:15125753..15137311
Sequence
Get Decorated FASTA
Genomic Maps
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
NCBI
UCSC
Ensembl
PopFly
Function
Gene Ontology (GO) Annotations (5 terms)
Molecular Function (1 term)
Terms Based on Experimental Evidence (0 terms)
Terms Based on Predictions or Assertions (1 term)
CV Term
Evidence
References
enables acyltransferase activity, transferring groups other than amino-acyl groups
inferred from electronic annotation with InterPro:IPR002656
(InterPro Project Members, 2004-)
Biological Process (3 terms)
Terms Based on Experimental Evidence (3 terms)
CV Term
Evidence
References
involved_in chitin-based cuticle development
inferred from mutant phenotype
(Dzitoyeva et al., 2003)
involved_in digestive system process
inferred from mutant phenotype
(Peller et al., 2009)
involved_in oogenesis
inferred from mutant phenotype
(Dzitoyeva et al., 2003)
Terms Based on Predictions or Assertions (0 terms)
Cellular Component (1 term)
Terms Based on Experimental Evidence (1 term)
CV Term
Evidence
References
located_in organelle membrane
inferred from direct assay
(Kim et al., 2012)
Terms Based on Predictions or Assertions (0 terms)
Gene Group (FlyBase)
Protein Family (UniProt)
-
Protein Signatures (InterPro)
Summaries
Gene Snapshot
drop dead (drd) encodes an integral membrane protein required for female fertility and for proper function of the gut and respiratory tracheae. [Date last reviewed: 2019-03-07]
Gene Group (FlyBase)
UNCLASSIFIED NON-AMINOACYL ACYLTRANSFERASES -
This group comprises non-aminoacyl acyltransferases that do not classify under other groups in FlyBase.
Phenotypic Description (Red Book; Lindsley and Zimm 1992)
drd: drop dead (J.C. Hall)
After normal development and normal behavior of young adults, flies begin to walk in uncoordinated manner and rapidly die (all dead by approximately ten days posteclosion); before death, there are gross holes in brain; mosaic experiment suggests primary defect is in brain. Second allele (drd2) causes similar effects with rapid death of population 9-11 days post eclosion plus reduced female fertility.
Gene Model and Products
Number of Transcripts
1
Number of Unique Polypeptides
1

Please see the JBrowse view of Dmel\drd for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)
Isoform displayed:
Pfam protein domains
InterPro name
classification
start
end
Protein Domains (via SMART)
Isoform displayed:
SMART protein domains
InterPro name
classification
start
end
Structure
Protein 3D structure   (Predicted by AlphaFold)   (AlphaFold entry Q8IR42)

If you don't see a structure in the viewer, refresh your browser.
Model Confidence:
  • Very high (pLDDT > 90)
  • Confident (90 > pLDDT > 70)
  • Low (70 > pLDDT > 50)
  • Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Experimentally Determined Structures
Crossreferences
Comments on Gene Model

Gene model reviewed during 5.50

Low-frequency RNA-Seq exon junction(s) not annotated.

Gene merge based on EST/cDNA data (RE74651)

Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Assoc. CDS (aa)
drd-RA
FBtr0100009
NM_001038756
3280
827
Additional Transcript Data and Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
UniProt
RefSeq ID
GenBank
drd-PA
FBpp0099994
93.6
827
8.74
Q8IR42
NP_001033845
AAN09655
Polypeptides with Identical Sequences

There is only one protein coding transcript and one polypeptide associated with this gene

Additional Polypeptide Data and Comments
Reported size (kDa)
Comments
External Data
Crossreferences
InterPro - A database of protein families, domains and functional sites
Linkouts
Sequences Consistent with the Gene Model
Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\drd using the Feature Mapper tool.

External Data
Crossreferences
Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
Linkouts
Expression Data
Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

-0.58

Transcript Expression
in situ
Stage
Tissue/Position (including subcellular localization)
Reference
third instar larval stage
embryonic/larval neuromuscular junction
(Dzitoyeva et al., 2003)
ring gland
(Dzitoyeva et al., 2003)
adult stage
interneuron
(Dzitoyeva et al., 2003)
interneuron of adult optic lobe
(Dzitoyeva et al., 2003)
corpus allatum
(Dzitoyeva et al., 2003)
neurosecretory neuron
(Dzitoyeva et al., 2003)
adult stage | female
ovarian sheath
(Dzitoyeva et al., 2003)
female accessory gland
(Dzitoyeva et al., 2003)
adult stage | male
male accessory gland
(Dzitoyeva et al., 2003)
in situ RT-PCR
Stage
Tissue/Position (including subcellular localization)
Reference
embryonic stage 8 -- 11
ventral neurectoderm
(Dzitoyeva et al., 2003)
embryonic stage 15 -- 16
presumptive embryonic/larval central nervous system
(Dzitoyeva et al., 2003)
northern blot
Stage
Tissue/Position (including subcellular localization)
Reference
adult stage | female
organism

Comment: heads and bodies assayed separately

(Dzitoyeva et al., 2003)
adult stage | male
organism

Comment: heads and bodies assayed separately

(Dzitoyeva et al., 2003)
RT-PCR
Stage
Tissue/Position (including subcellular localization)
Reference
embryonic stage 17 -- adult stage
organism

Comment: 7-16 hr AEL not assayed

(Dzitoyeva et al., 2003)
Additional Descriptive Data
Marker for
 
Subcellular Localization
CV Term
Polypeptide Expression
immunolocalization
Stage
Tissue/Position (including subcellular localization)
Reference
embryonic stage
embryonic/larval tracheal section
(Kim et al., 2012)
third instar larval stage
embryonic/larval hindgut
(Kim et al., 2012)
larval hindgut imaginal ring
(Kim et al., 2012)
pharate adult stage
pupal tracheal section

Comment: authors state "late (darkly pigmented)" pupa

(Kim et al., 2012)
embryonic/larval proventriculus intermediate layer

Comment: authors state "late (darkly pigmented)" pupa

(Kim et al., 2012)
crop

Comment: authors state "late (darkly pigmented)" pupa

(Kim et al., 2012)
pupal epidermis

Comment: authors state "late (darkly pigmented)" pupa

(Kim et al., 2012)
adult stage
adult tracheal section
(Kim et al., 2012)
cone cell
(Kim et al., 2012)
oogenesis stage S10 -- S13 & adult stage | female
follicle cell
(Kim et al., 2012)
mass spectroscopy
Stage
Tissue/Position (including subcellular localization)
Reference
adult stage
adult head
(Aradska et al., 2015)
Additional Descriptive Data

In third instar larvae, drd protein is expressed in the hindgut and the hindgut imaginal cells (thin arrow), but not in the midgut or the Malpighian tubules.

(Kim et al., 2012)
Marker for
 
Subcellular Localization
CV Term
Evidence
References
located_in organelle membrane
inferred from direct assay
(Kim et al., 2012)
Expression Deduced from Reporters
Reporter: PBac{681.P.FSVS-1}drdCPTI001223
Stage
Tissue/Position (including subcellular localization)
Reference
adult stage
adult brain cell body rind
(Knowles-Barley, 2011.8.24)
High-Throughput Expression Data
Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\drd in JBrowse
RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region
Bulk Downloads
RNA-Seq RPKM values for all genes
Reference
See Gelbart and Emmert, 2013 for analysis details and data files for all genes.
Developmental Proteome: Life Cycle
Developmental Proteome: Embryogenesis
External Data and Images
Linkouts
DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species
EMBL-EBI Single Cell Expression Atlas - Single cell expression across species
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data
Flygut - An atlas of the Drosophila adult midgut
Images
FlyBase Wiki
Image Based Resources
Alleles, Insertions, Transgenic Constructs, and Aberrations
Classical and Insertion Alleles ( 16 )
For All Classical and Insertion Alleles Show
 
Other relevant insertions
Transgenic Constructs ( 6 )
For All Alleles Carried on Transgenic Constructs Show
Transgenic constructs containing/affecting coding region of drd
Transgenic constructs containing regulatory region of drd
Aberrations (Deficiencies and Duplications) ( 5 )
Variants
Variant Molecular Consequences
Alleles Representing Disease-Implicated Variants
Phenotypes
For more details about a specific phenotype click on the relevant allele symbol.
Lethality
Allele
lethal
lethal (with drdCB-6275-3)
lethal (with drdlwf)
lethal | recessive
viable
viable, with Dcr-2UAS.cDa, Scer\GAL4elav.PLu
viable, with Scer\GAL4DJ626
viable, with Scer\GAL4drd-MI15121-TG4.1
viable, with Scer\GAL4Mef2.PR
viable, with Scer\GAL4pnr-MD237
Sterility
Allele
female semi-fertile
female sterile
female sterile (with drd1)
female sterile (with drdlwf)
fertile (with drdCB-6275-3)
fertile (with drdlwf)
Other Phenotypes
Allele
abnormal behavior | adult stage
abnormal feeding behavior
abnormal neuroanatomy
abnormal neuroanatomy, with Scer\GAL4DJ626
decreased body size
decreased body size (with drd1)
decreased body size (with drdlwf)
decreased rate of movement
increased size | adult stage | recessive
short lived
short lived, with Scer\GAL4DJ626
short lived (with drd1)
short lived (with drdlwf)
short lived | conditional, with Scer\GAL4hs.PB
short lived | heat sensitive
short lived | male, with Scer\GAL4Act5C.PI
short lived | male | heat sensitive, with Scer\GAL4hs.PB
short lived | nutrition conditional
some die during immature adult stage | recessive
some die during immature adult stage | recessive (with drdCB-6275-3)
some die during immature adult stage | recessive (with drdlwf)
visible
Phenotype manifest in
Allele
abdomen
adult brain
adult brain, with Scer\GAL4DJ626
adult gut, with Scer\GAL4DJ626
adult gut, with Scer\GAL4DJ717
adult midgut
adult optic lobe
adult peritrophic membrane
adult peritrophic membrane, with Scer\GAL4DJ626
adult peritrophic membrane, with Scer\GAL4DJ717
adult peritrophic membrane | conditional, with Scer\GAL4hs.PB
adult proventriculus
crop
crop (with drd1)
crop (with drdCB-6275-3)
crop (with drdlwf)
egg chamber
egg chamber (with drd1)
egg chamber (with drdCB-6275-3)
egg chamber (with drdlwf)
glial cell & adult brain
wing
Orthologs
Downloads
Download All DIOPT Orthologs
Human Orthologs (via DIOPT v9.1)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
Domainoid
eggNOG
Hieranoid
Homologene
Inparanoid
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
SonicParanoid
Alignment
Complementation?
Transgene?
Homo sapiens (Human) (0)
Model Organism Orthologs (via DIOPT v9.1)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
Domainoid
eggNOG
Hieranoid
Homologene
Inparanoid
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
SonicParanoid
Alignment
Complementation?
Transgene?
Rattus norvegicus (Norway rat) (1)
Rnor\Oacyl
4 of 14
Yes
No
Mus musculus (laboratory mouse) (1)
Mmus\Oacyl
3 of 14
Yes
No
Xenopus tropicalis (Western clawed frog) (1)
Xtro\LOC101732251
1 of 13
Yes
No
Danio rerio (Zebrafish) (1)
Drer\oacyl
4 of 14
Yes
No
Caenorhabditis elegans (Nematode, roundworm) (38)
Cele\ndg-4
4 of 14
Yes
Yes
Cele\oac-9
4 of 14
Yes
Yes
Cele\oac-39
4 of 14
Yes
No
Cele\oac-55
4 of 14
Yes
No
Cele\nrf-6
3 of 14
No
No
Cele\oac-3
3 of 14
No
No
Cele\oac-5
3 of 14
No
No
Cele\oac-6
3 of 14
No
No
Cele\oac-7
3 of 14
No
No
Cele\oac-14
3 of 14
No
No
Cele\oac-20
3 of 14
No
No
Cele\oac-31
3 of 14
No
No
Cele\oac-32
3 of 14
No
No
Cele\oac-46
3 of 14
No
No
Cele\oac-50
3 of 14
No
No
Cele\oac-53
3 of 14
No
No
Cele\oac-54
3 of 14
No
No
Cele\rhy-1
3 of 14
No
No
Cele\bus-1
1 of 14
No
Yes
Cele\oac-2
1 of 14
No
Yes
Cele\oac-10
1 of 14
No
Yes
Cele\oac-12
1 of 14
No
Yes
Cele\oac-19
1 of 14
No
Yes
Cele\oac-24
1 of 14
No
Yes
Cele\oac-26
1 of 14
No
Yes
Cele\oac-27
1 of 14
No
Yes
Cele\oac-30
1 of 14
No
Yes
Cele\oac-37
1 of 14
No
Yes
Cele\oac-38
1 of 14
No
Yes
Cele\oac-40
1 of 14
No
Yes
Cele\oac-41
1 of 14
No
Yes
Cele\oac-43
1 of 14
No
Yes
Cele\oac-44
1 of 14
No
Yes
Cele\oac-45
1 of 14
No
Yes
Cele\oac-48
1 of 14
No
Yes
Cele\oac-49
1 of 14
No
Yes
Cele\oac-56
1 of 14
No
Yes
Cele\oac-57
1 of 14
No
Yes
Anopheles gambiae (African malaria mosquito) (26)
Agam\AgaP_AGAP000629
12 of 12
Yes
Yes
Agam\AgaP_AGAP000520
4 of 12
No
Yes
Agam\AgaP_AGAP013491
4 of 12
No
Yes
Agam\AgaP_AGAP000521
3 of 12
No
No
Agam\AgaP_AGAP000535
3 of 12
No
No
Agam\AgaP_AGAP001485
3 of 12
No
No
Agam\AgaP_AGAP003010
3 of 12
No
No
Agam\AgaP_AGAP003499
3 of 12
No
No
Agam\AgaP_AGAP004694
3 of 12
No
Yes
Agam\AgaP_AGAP003510
2 of 12
No
No
Agam\AgaP_AGAP005145
2 of 12
No
No
Agam\AgaP_AGAP005146
2 of 12
No
No
Agam\AgaP_AGAP007069
2 of 12
No
No
Agam\AgaP_AGAP007070
2 of 12
No
No
Agam\AgaP_AGAP007071
2 of 12
No
No
Agam\AgaP_AGAP007072
2 of 12
No
No
Agam\AgaP_AGAP007073
2 of 12
No
No
Agam\AgaP_AGAP007074
2 of 12
No
No
Agam\AgaP_AGAP007075
2 of 12
No
No
Agam\AgaP_AGAP007076
2 of 12
No
Yes
Agam\AgaP_AGAP007077
2 of 12
No
No
Agam\AgaP_AGAP007078
2 of 12
No
No
Agam\AgaP_AGAP007079
2 of 12
No
No
Agam\AgaP_AGAP007659
2 of 12
No
No
Agam\AgaP_AGAP012821
2 of 12
No
No
Agam\AgaP_AGAP007510
1 of 12
No
No
Arabidopsis thaliana (thale-cress) (0)
Saccharomyces cerevisiae (Brewer's yeast) (0)
Schizosaccharomyces pombe (Fission yeast) (0)
Escherichia coli (enterobacterium) (0)
Other Organism Orthologs (via OrthoDB)
Data provided directly from OrthoDB:drd. Refer to their site for version information.
Paralogs
Downloads
Download All DIOPT Paralogs
Paralogs (via DIOPT v9.1)
Gene Symbol
Score
Source
Compara
Domainoid
eggNOG
Homologene
Inparanoid
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
SonicParanoid
Alignment
Drosophila melanogaster (Fruit fly) (19)
CG3106
5 of 13
CG10182
5 of 13
CG10183
5 of 13
CG13325
5 of 13
CG14204
5 of 13
CG14205
5 of 13
CG14219
5 of 13
CG16723
5 of 13
CG33337
5 of 13
CG42329
5 of 13
CG5892
4 of 13
CG11353
4 of 13
CG12990
4 of 13
CG17707
4 of 13
CG30471
4 of 13
CG32645
4 of 13
CG4576
3 of 13
CG9447
2 of 13
CG30467
1 of 13
Human Disease Associations
FlyBase Human Disease Model Reports
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Evidence
    References
    Potential Models Based on Orthology ( 0 )
    Human Ortholog
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Interaction
    References
    Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)
    Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
    Homo sapiens (Human)
    Gene name
    Score
    OMIM
    OMIM Phenotype
    DO term
    Complementation?
    Transgene?
    Functional Complementation Data
    Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
    Interactions
    Summary of Physical Interactions
    Interaction Browsers
    Summary of Genetic Interactions
    Interaction Browsers
    Starting gene(s)
    Interaction type
    Interacting gene(s)
    Reference
    Starting gene(s)
    Interaction type
    Interacting gene(s)
    Reference
    External Data
    Linkouts
    DroID - A comprehensive database of gene and protein interactions.
    MIST (protein-protein) - An integrated Molecular Interaction Database
    Pathways
    Signaling Pathways (FlyBase)
    Metabolic Pathways
    FlyBase
    External Links
    External Data
    Linkouts
    Class of Gene
    Genomic Location and Detailed Mapping Data
    Chromosome (arm)
    X
    Recombination map
    1-50
    Cytogenetic map
    13A12-13B1
    Sequence location
    FlyBase Computed Cytological Location
    Cytogenetic map
    Evidence for location
    13A12-13B1
    Limits computationally determined from genome sequence between P{EP}hiwEP1308 and P{EP}Ahcy13EP1007
    Experimentally Determined Cytological Location
    Cytogenetic map
    Notes
    References
    13A-13B
    (Kretzschmar et al., 1993)
    Experimentally Determined Recombination Data
    Location

    1-50

    (FlyBase, 2016)

    1-50.1

    (Comeron et al., 2012)

    1-33-57

    Left of (cM)
    (Homyk et al., 1986)
    Right of (cM)
    (Homyk et al., 1986)
    (Homyk et al., 1986)
    Notes
    Stocks and Reagents
    Stocks (7)
    Genomic Clones (11)
     

    Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

    cDNA Clones (97)
     

    Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

    cDNA clones, fully sequenced
    BDGP DGC clones
    Other clones
      Drosophila Genomics Resource Center cDNA clones

      For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

      cDNA Clones, End Sequenced (ESTs)
      BDGP DGC clones
      Other clones
      RNAi and Array Information
      Linkouts
      DRSC - Results frm RNAi screens
      Antibody Information
      Laboratory Generated Antibodies
       

      monoclonal

      (Kim et al., 2012)
      Commercially Available Antibodies
       
      Cell Line Information
      Publicly Available Cell Lines
       
        Other Stable Cell Lines
         
          Other Comments

          Mutant flies show a reduction in the transfer of ingested food from the crop to the midgut and an increased rate of crop contraction compared to controls.

          (Peller et al., 2009)

          Mutations in drd result in early adult lethality and neurodegeneration.

          (Blumenthal, 2008)

          Mutant drd flies store significantly more food in their crops and defecate less than wild-type flies.

          (Blumenthal, 2008)

          Identification: In an EMS screen for mutations that confer salt sensitivity in Drosophila.

          (Blumenthal, 2004)

          The lwf EMS line exhibits lethality within 5 days on food containing 0.4 M NaCl. The lwf EMS line has a normal body size and external morphology.

          (Blumenthal, 2004)

          Embryos in which beltless function has been reduced using RNA interference display a range of cuticular defects, ranging from partially differentiated cuticle to misdirected and partially formed denticle belts, and lack of denticle belts in abdominal segments A2-A4. The embryos fail to hatch.

          (Dzitoyeva et al., 2003)

          The ovaries of adult females in which beltless function has been reduced using RNA interference are smaller than normal 72 hours after treatment with dsRNA, and the connections between the ovarioles are disorganised and loose. These females lay significantly fewer eggs than controls.

          (Dzitoyeva et al., 2003)

          Approximately 65% of beltless RNAi embryos develop cuticular abnormalities, ranging from partially differentiated cuticle to misdirected and only partially-formed denticle belts.

          (Dzitoyeva et al., 2003)

          New annotation (CG32589) in release 3 of the genome annotation.

          (FlyBase Genome Annotators, 2002-2003)

          In drd mutants the temporal pattern of expression of three different molecular biomarkers is accelerated.

          (Rogina et al., 1997)

          The expression pattern of drd suggests the gene function is required in specific glial cell types that play a role in the maintenance of brain integrity.

          (Kretzschmar and Benzer, 1995)

          Adult mutants exhibit severe behavioural defects and brain degeneration, these manifest a few days after emergence. Mosaic analysis reveals the drd gene product is non-cell autonomous. Defective glia in the adult brain may disrupt adult nervous system function, contributing to progressive brain degeneration and death. The wild type drd gene product may prevent brain degeneration by providing a necessary glial function.

          (Buchanan and Benzer, 1993)

          After normal development and normal behavior of young adults, flies begin to walk in uncoordinated manner and rapidly die (all dead by approximately ten days posteclosion); before death, there are gross holes in brain; mosaic experiment suggests primary defect is in brain. Second allele (drd2) causes similar effects with rapid death of population 9-11 days post-eclosion plus reduced female fertility.

          Relationship to Other Genes
          Source for database merge of

          Source for merge of: lwf CG33968

          (Blumenthal, 2007)

          Source for merge of: drd beltless

          (Blumenthal, 2008)

          Source for merge of: CG32589 CG5652

          (FlyBase Genome Annotators, 2005)
          Additional comments

          Annotations CG32589 and CG5652 merged as CG33968 in release 4.3 of the genome annotation.

          (FlyBase Genome Annotators, 2005)

          Not allelic to any of six adult-lethal (adl) genes mapping between v and f.

          Nomenclature History
          Source for database identify of

          Source for identity of: BcDNA:GM06434 CG5652

          (Wang, 1999.11)

          Source for identity of: beltless CG5652

          (Dzitoyeva et al., 2003)
          Nomenclature comments
          Etymology

          The gene is named "beltless" based on the embryonic loss of function phenotype of missing denticle belts.

          (Dzitoyeva et al., 2003)
          Synonyms and Secondary IDs (13)
          Datasets (0)
          Study focus (0)
          Experimental Role
          Project
          Project Type
          Title
          Study result (0)
          Result
          Result Type
          Title
          External Crossreferences and Linkouts ( 35 )
          Sequence Crossreferences
          NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
          GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
          GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
          RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.
          UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.
          UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information
          Other crossreferences
          AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.
          DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species
          EMBL-EBI Single Cell Expression Atlas - Single cell expression across species
          FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data
          InterPro - A database of protein families, domains and functional sites
          KEGG Genes - Molecular building blocks of life in the genomic space.
          MARRVEL_MODEL - MARRVEL (model organism gene)
          Linkouts
          Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones
          DroID - A comprehensive database of gene and protein interactions.
          DRSC - Results frm RNAi screens
          Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
          FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
          FlyCyc Genes - Genes from a BioCyc PGDB for Dmel
          Flygut - An atlas of the Drosophila adult midgut
          iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)
          MIST (protein-protein) - An integrated Molecular Interaction Database
          References (77)