None of the polypeptides share 100% sequence identity.
Selectively interacts (via UBR-type zinc finger) with the cleaved form of Diap1; this interaction is enhanced by tal (PubMed:25146930, PubMed:26383956). Interacts with tal and Rrp1 (PubMed:26383956). Interacts with ovo isoform B (via N-terminus) (PubMed:26383956). Interacts with Cad99C (via the cytoplasmic domain) (PubMed:27331610). Interacts with ck and Sans (PubMed:27331610). Interacts with cos (via Kinesin motor domain) (PubMed:27195754).
In vitro, self-ubiquitination in the presence of E1, E2 and ubiquitin.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Ubr3 using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\Ubr3 in GBrowse 2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: Ubr3 CG42593
Source for merge of: CG1531 CG1530
Named 'Ubr3' after its mammalian homolog.