DmCNGC, Cng, Cyclic-nucleotide-gated ion channel protein
Gene model reviewed during 5.50
Gene model reviewed during 5.55
None of the polypeptides share 100% sequence identity.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\CngA using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\CngA in GBrowse 2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: CngA Cng
Source for merge of: Cng CG15709
Annotations CG7779 and CG15709 merged as CG42701 in release 5.26 of the genome annotation.
The use of a reporter gene fusion to study the topology of proteins in a membrane has been used to determine the topology of the Cng channel.
The Cng channel gene has been cloned and is expressed in the visual and olfactory system. The electrical properties of the cloned cyclic nucleotide gated (CNG) channel resemble those of light activated channels in photoreceptors. The channel is highly permeable to calcium ions suggesting that it mediates a light induced calcium ions entry into cells. These results support the notion that CNG channels are involved in the transduction of light and chemical stimuli in invertebrates.