Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\mir-let7 using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\mir-let7 in GBrowse 2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: mir-let7 let-7
The annotation for let-7 has been changed in release 5.31 of the genome annotation, so that instead of representing a mature miRNA it now represents the precursor stem loop pre-miRNA. The symbol of the annotation has been changed from CR32968 to CR42949 to reflect this change.
Added 'mir-' prefix to be consistent with miRNA naming conventions in FlyBase, and thereby indicate the gene encodes a miRNA in its symbol.
The three microRNAs let-7, mir-125 and mir-100 are co-transcribed as a single polycistronic transcription unit (the "let-7-Complex, let-7-C").
let-7 is required to ensure the appropriate remodeling of the abdominal neuromusculature during the larval-to-adult transition.
New annotation (CR32968) in release 3 of the genome annotation.
Hormone induced expression of let-7 may control developmental stage transitions.