FlyBase Gene Report: Dmel\bru2

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\bru2 using the Feature Mapper tool.

External Data

Crossreferences

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

Linkouts

Expression Data

Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

-0.53

Transcript Expression

in situ

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 1 -- 3

organism

Comment: maternally deposited

(Fisher et al., 2012)

embryonic stage 4 -- 6

organism

Comment: rapidly degraded

(Fisher et al., 2012)

embryonic stage 7 -- 8

anterior endoderm anlage

(Fisher et al., 2012)

head mesoderm

(Fisher et al., 2012)

posterior endoderm

(Fisher et al., 2012)

trunk mesoderm

(Fisher et al., 2012)

embryonic stage 9 -- 10

anterior endoderm

(Fisher et al., 2012)

head mesoderm

(Fisher et al., 2012)

embryonic stage 11 -- 12

head mesoderm

(Fisher et al., 2012)

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

mass spectroscopy

Stage

Tissue/Position (including subcellular localization)

Reference

adult stage

adult head

• membrane

(Aradska et al., 2015)

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Evidence

References

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\bru2 in JBrowse

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\bru2

View exonic expression by tissue for Dmel\bru2

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0262475

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

250811/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0262475

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0262475

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG31761

Images

FlyBase Wiki

Image Based Resources

Alleles, Insertions, Transgenic Constructs, and Aberrations

Classical and Insertion Alleles ( 14 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 8 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of bru2

Transgenic constructs containing regulatory region of bru2

Aberrations (Deficiencies and Duplications) ( 0 )

Inferred from experimentation ( 0 )

Inferred from location ( 8 )

Variants

Variant Molecular Consequences

Alleles Representing Disease-Implicated Variants

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

viable

bru2^f00171

Sterility

Allele

fertile

bru2^f00171

Phenotype manifest in

Allele

Orthologs

Downloads

Download All DIOPT Orthologs

Human Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Homo sapiens (Human) (82)

Hsap\CELF2

9 of 14

Yes

8 of 14

7 of 14

7 of 14

6 of 14

6 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

144

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Model Organism Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Rattus norvegicus (Norway rat) (56)

Rnor\Celf1

8 of 14

Yes

Rnor\Celf2

8 of 14

Yes

7 of 14

7 of 14

7 of 14

5 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Mus musculus (laboratory mouse) (80)

Mmus\Celf1

8 of 14

Yes

Mmus\Celf2

8 of 14

Yes

7 of 14

7 of 14

6 of 14

6 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Xenopus tropicalis (Western clawed frog) (55)

Xtro\celf2

7 of 13

Yes

6 of 13

4 of 13

4 of 13

3 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Danio rerio (Zebrafish) (72)

Drer\celf2

8 of 14

Yes

7 of 14

7 of 14

7 of 14

6 of 14

6 of 14

5 of 14

5 of 14

2 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Drer\LOC110437789

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Caenorhabditis elegans (Nematode, roundworm) (39)

Cele\etr-1

10 of 14

Yes

7 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Anopheles gambiae (African malaria mosquito) (55)

Agam\AgaP_AGAP009477

7 of 12

Yes

Agam\AgaP_AGAP004950

4 of 12

Agam\AgaP_AGAP009474

3 of 12

Yes

Agam\AgaP_AGAP009475

3 of 12

Yes

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

Arabidopsis thaliana (thale-cress) (91)

Atha\AT1G03457

11 of 13

Yes

Atha\RBP-DR1

11 of 13

Yes

Atha\FCA

7 of 13

Yes

Atha\AT2G47310

5 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Saccharomyces cerevisiae (Brewer's yeast) (21)

Scer\GBP2

2 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Yes

Scer\NOP15

1 of 13

Scer\NPL3

1 of 13

Scer\NSR1

1 of 13

Yes

Scer\PAB1

1 of 13

Scer\PUB1

1 of 13

Scer\RIE1

1 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Yes

Scer\YRA1

1 of 13

Scer\YRA2

1 of 13

Yes

Schizosaccharomyces pombe (Fission yeast) (14)

Spom\cwf5

1 of 12

Yes

Spom\mlo3

1 of 12

Yes

Spom\nop12

1 of 12

Yes

Spom\pabp

1 of 12

Yes

Spom\SPAC22E12.02

1 of 12

Yes

Spom\SPAC25G10.01

1 of 12

Yes

Spom\SPAC328.05

1 of 12

Yes

Spom\SPBC4F6.14

1 of 12

Yes

Spom\SPBC106.12c

1 of 12

Yes

Spom\SPBC660.15

1 of 12

Yes

Spom\SPBP22H7.02c

1 of 12

Yes

Spom\SPCC1827.05c

1 of 12

Yes

Spom\spo5

1 of 12

Yes

Spom\tif35

1 of 12

Yes

Escherichia coli (enterobacterium) (0)

Other Organism Orthologs (via OrthoDB)

Data provided directly from OrthoDB:bru2. Refer to their site for version information.

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v9.1)

Gene Symbol

Score

Source

Alignment

Drosophila melanogaster (Fruit fly) (57)

bru1

10 of 13

bru3

10 of 13

Sxl

3 of 13

CG4612

2 of 13

CG4806

2 of 13

elav

2 of 13

fne

2 of 13

maca

2 of 13

pAbp

2 of 13

shep

2 of 13

Spx

2 of 13

ssx

2 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

LS2

1 of 13

mod

1 of 13

msi

1 of 13

nito

1 of 13

nonA-l

1 of 13

nonA

1 of 13

Pof

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

sqd

1 of 13

Syp

1 of 13

TBPH

1 of 13

trv

1 of 13

tut

1 of 13

U2af50

1 of 13

Human Disease Associations

FlyBase Human Disease Model Reports

Alzheimer disease, susceptibility to (postulated), CELF1-related

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 1 )

Human Ortholog

Disease

Evidence

References

CELF2; CUGBP Elav-like family member 2

model of developmental and epileptic encephalopathy 97

IEA

(FlyBase, 2019-)

Modifiers Based on Experimental Evidence ( 1 )

Allele

Disease

Interaction

References

bru2^G5819

ameliorates tauopathy

modeled by Hsap\MAPT^UAS.cWa

(Bernstein et al., 2016)

modeled by Hsap\MAPT^V337M.UAS

(Bernstein et al., 2016)

modeled by Hsap\MAPT^R406W.UAS

(Bernstein et al., 2016)

Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

CELF2; CUGBP Elav-like family member 2

9 of 14

602538

DEVELOPMENTAL AND EPILEPTIC ENCEPHALOPATHY 97; DEE97

developmental and epileptic encephalopathy 97

CELF1; CUGBP Elav-like family member 1

8 of 14

CUGBP- AND ELAV-LIKE FAMILY, MEMBER 1; CELF1

CELF3; CUGBP Elav-like family member 3

7 of 14

612678

CELF4; CUGBP Elav-like family member 4

7 of 14

612679

CELF5; CUGBP Elav-like family member 5

6 of 14

612680

CELF6; CUGBP Elav-like family member 6

6 of 14

612681

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

Interaction Browsers

Summary of Genetic Interactions

Interaction Browsers

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

External Data

Linkouts

DroID - A comprehensive database of gene and protein interactions.

FBgn0262475

Pathways

Signaling Pathways (FlyBase)

Metabolic Pathways

FlyBase

External Links

External Data

Linkouts

Class of Gene

nuclear_gene

protein_coding_gene

Genomic Location and Detailed Mapping Data

Chromosome (arm)

Recombination map

2-46

Cytogenetic map

33E1-33E3

Sequence location

2L:12,344,219..12,397,528 [+]

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

33E1-33E3

Limits computationally determined from genome sequence between P{PZ}Rab6⁰⁸³²³ and P{EP}Elf^EP476&P{EP}bun^EP488

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

2-46

(FlyBase, 2016)

2-40.7

(Comeron et al., 2012)

Left of (cM)

Right of (cM)

Notes

Stocks and Reagents

Stocks (22)

Aberrations including deletions of this gene Aberrations including duplications of this gene

Bloomington

18300

w¹¹¹⁸; PBac{WH}bru2^f00171

50627

y¹ v¹; P{TRiP.HMC02994}attP40

63350

w¹¹¹⁸; PBac{IT.GAL4}bru2^0482-G4

77649

w¹¹¹⁸; PBac{IT.GAL4}bru2^4033-G4

27190

y¹ w^*; P{EP}bru2^G5819/CyO

38574

y¹ w^*; Mi{MIC}bru2^MI04687

63747

w¹¹¹⁸; PBac{IT.GAL4}bru2^0691-G4/CyO

NIG-Fly

31763R-2

P{NIG.31763R}2

HMC02994

y¹ v¹; P{TRiP.HMC02994}attP40

HMJ23500

y¹ v¹; P{TRiP.HMJ23500}attP40/CyO

VDRC

v104949

P{KK112429}VIE-260B

v109739

P{KK108932}VIE-260B

More stocks available...

Genomic Clones (40)

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (32)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced

BDGP DGC clones

LD19052

Other clones

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

FBgn0262475

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi and Array Information

Linkouts

DRSC - Results frm RNAi screens

FBgn0262475

Antibody Information

Laboratory Generated Antibodies

Commercially Available Antibodies

Cell Line Information

Publicly Available Cell Lines

Other Stable Cell Lines

Other Comments

RNAi generated by PCR using primers directed to this gene causes a cell growth and viability phenotype when assayed in Kc167 and S2R⁺ cells.

(Boutros et al., 2004)

New annotation (CG31763) in release 3 of the genome annotation.

(FlyBase Genome Annotators, 2002-2003)

Immediately adjacent to the aret gene.

(Good et al., 2000)

Relationship to Other Genes

Source for database merge of

Source for merge of: bru-2 CG31763

(FlyBase Genome Annotators, 2010)

Additional comments

Annotations CG31761 and CG31763 merged as CG43065 in release 5.31 of the genome annotation.

(FlyBase Genome Annotators, 2010)

Annotation CG6319 split into CG31761 (bru-2) and CG31762 (aret) in release 3 of the genome annotation. Release 3 annotation CG31761 (bru-2) contains sequences corresponding to release 2 annotation CG17008 and part of release 2 annotation CG6319.

(FlyBase Genome Annotators, 2002-2003)

Nomenclature History

Source for database identify of

Source for identity of: bru2 bru-2

(FlyBase, 2009-)

Nomenclature comments

Etymology

Synonyms and Secondary IDs (12)

Reported As

Symbol Synonym

Bru-2

(Delaunay et al., 2004)

CG17008

(Boutros et al., 2004)

CG31761

(Keleman et al., 2009.8.5, Quinones-Coello, 2007, Philipps et al., 2004)

CG31763

(Fukuoh et al., 2014, Japanese National Institute of Genetics, 2012.5.21, Friedman et al., 2011, Keleman et al., 2009.8.5)

CG43065

(National Institute of Genetics Fly Stocks, 2023-, National Institute of Genetics Fly Stocks, 2022-, FlyBase Genome Annotators, 2010, Ni et al., 2010.12.1)

CG6319

(Good, 2000.3.24, Good et al., 2000)

Dm Bru-2

(Horb and Horb, 2010, Good et al., 2000)

bru-2

(Ugrankar et al., 2018, Bernstein et al., 2016, Clandinin and Owens, 2016-, Hunter et al., 2016, Aradska et al., 2015, Gene Disruption Project members, 2015-, Ashwal-Fluss et al., 2014, Hughes et al., 2014, Chintapalli et al., 2013, Vaque et al., 2013, Kwon et al., 2009, Quinones-Coello, 2007, Burgler and Macdonald, 2005, Philipps et al., 2004)

bru2

(Li et al., 2024, Winbush and Singh, 2021, Ghosh et al., 2020, Trcek and Lehmann, 2019, Clandinin and Owens, 2016-)

Name Synonyms

bruno 2

bruno-2

(Lawlor et al., 2011, Good et al., 2000)

bruno2

(Vicente-Crespo et al., 2008)

Secondary FlyBase IDs

FBgn0043904
FBgn0032423
FBgn0051761
FBgn0051763

Datasets (0)

Study focus (0)

Experimental Role

Project

Project Type

Title

Study result (0)

Result

Result Type

Title

External Crossreferences and Linkouts ( 68 )

Sequence Crossreferences

NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

250811

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.

UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.

Q0E8R3

UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information

Other crossreferences

AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.

Q0E8R3

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0262475

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

250811/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0262475

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0262475

InterPro - A database of protein families, domains and functional sites

KEGG Genes - Molecular building blocks of life in the genomic space.

dme:Dmel_CG43065

MARRVEL_MODEL - MARRVEL (model organism gene)

250811

Linkouts

Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones

FBgn0262475

DroID - A comprehensive database of gene and protein interactions.

FBgn0262475

DRSC - Results frm RNAi screens

FBgn0262475

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FlyCyc Genes - Genes from a BioCyc PGDB for Dmel

FBGN0262475

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG31761

References (59)

The following external sites may use different assemblies or annotations than FlyBase.

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