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FB2026_01
,
released March 12, 2026
mun, munin
a GPI-anchored membrane protein with four GDNF family receptor-like domains - regulates oogenesis and male fertility - expressed in the central and peripheral nervous systems
Please see the JBrowse view of Dmel\Gfrl for information on other features
To submit a correction to a gene model please use the Contact FlyBase form
AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Gene model reviewed during 5.50
Gene model reviewed during 5.44
Stop-codon suppression (UGA) postulated; FBrf0216884.
Gene model reviewed during 5.56
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Gfrl using the Feature Mapper tool.
The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).
Comment: Transcript of 7000nt with stronger expression than 7500nt
Comment: Similar expression level for transcripts of 7000 and 7500nt.
Comment: Similar expression level for transcripts of 7000 and 7500nt.
Comment: Assay specific to exons 2-16 identified transcript B (2.6kb) and Bb (2.3kb)
Comment: Probe corresponding to exons 15-23 identified one major ~1kb band
Comment: Assay specific to exons 2-16 identified transcript B (2.6kb) and Bb (2.3kb)
Comment: Assay specific to exons 2-16 identified transcript B (2.6kb) and Bb (2.3kb)
Gfrl transcript is detected at stage 13 in the ventral neuroectoderm of seven abdominal segments, in single or small clusters of neurons located laterally or on both sides of the midline, and in cell clusters close to the oesophagus. In later embryonic stages expression is observed in all segments of the ventral nerve cord and in single neurons or neuron clusters located more laterally, throughout the peripheral sensory nervous system and in the dorsal vessel. In third instar larva, Gfrl transcript is observed in symmetric regions of the posterior brain lobes. In the adult, expression is mostly detected in the brain cortex.
JBrowse - Visual display of RNA-Seq signals
View Dmel\Gfrl in JBrowse3-68
3-72.6
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
polyclonal
Source for merge of: CG34118 CG17208
Source for merge of: CG17205 BcDNA:GH26447
Source for merge of: mun CG4342
Source for merge of: CG34119 mun
Source for merge of: mun CG17203
Source for merge of: CG42801 mun
Annotations CG42801 and CG42625 merged as CG43224 in release 5.34 of the genome annotation.
Annotations CG34118 and CG17208 merged as CG42801 in release 5.30 of the genome annotation.
Annotations CG34119 and CG34352 merged as CG42625 in release 5.21 of the genome annotation.
Annotations mun and CG4342 merged as CG42401 in release 5.10 of the genome annotation.
Source for merge of CG17205 BcDNA:GH26447 was a shared cDNA ( date:030728 ).
Annotation CG17205 split into CG34118 and CG34119 in release 5.1 of the genome annotation.
Annotations CG17203 and CG17204 merged as CG33518 (which corresponds to mun) in release 4.1 of the genome annotation.
Source for identity of: mun CG17204
Source for identity of: Gfrl mun
