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General Information
Symbol
Dmel\Gr39a
Species
D. melanogaster
Name
Gustatory receptor 39a
Annotation Symbol
CG31622
Feature Type
FlyBase ID
FBgn0264556
Gene Model Status
Stock Availability
Gene Summary
Gustatory receptor 39a (Gr39a) encodes a member of the gustatory receptors and is expressed in gustatory sensilla receptor neurons. They detect tastants (non-volatile compounds) via contact chemosensation. [Date last reviewed: 2019-03-07] (FlyBase Gene Snapshot)
Also Known As

Gr39a.a, Gr39a.d, Gr39a.b, Gr39aA, Gr39aD

Key Links
Genomic Location
Cytogenetic map
Sequence location
2L:21,290,734..21,297,686 [+]
Recombination map
2-54
RefSeq locus
NT_033779 REGION:21290734..21297686
Sequence
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
Function
GO Summary Ribbons
Gene Ontology (GO) Annotations (7 terms)
Molecular Function (1 term)
Terms Based on Experimental Evidence (0 terms)
Terms Based on Predictions or Assertions (1 term)
CV Term
Evidence
References
non-traceable author statement
(assigned by UniProt )
Biological Process (2 terms)
Terms Based on Experimental Evidence (1 term)
CV Term
Evidence
References
inferred from mutant phenotype
Terms Based on Predictions or Assertions (1 term)
CV Term
Evidence
References
non-traceable author statement
(assigned by UniProt )
inferred from electronic annotation with InterPro:IPR013604
(assigned by InterPro )
Cellular Component (4 terms)
Terms Based on Experimental Evidence (0 terms)
Terms Based on Predictions or Assertions (4 terms)
CV Term
Evidence
References
located_in axon
inferred from biological aspect of ancestor with PANTHER:PTN000475107
(assigned by GO_Central )
located_in dendrite
inferred from biological aspect of ancestor with PANTHER:PTN000475107
(assigned by GO_Central )
inferred from electronic annotation with InterPro:IPR013604
(assigned by InterPro )
non-traceable author statement
(assigned by UniProt )
inferred from biological aspect of ancestor with PANTHER:PTN000475107
(assigned by GO_Central )
Gene Group (FlyBase)
Protein Family (UniProt)
Belongs to the insect chemoreceptor superfamily. Gustatory receptor (GR) family. Gr21a subfamily. (P58956P58957P58958P58959)
Protein Signatures (InterPro)
Summaries
Gene Snapshot
Gustatory receptor 39a (Gr39a) encodes a member of the gustatory receptors and is expressed in gustatory sensilla receptor neurons. They detect tastants (non-volatile compounds) via contact chemosensation. [Date last reviewed: 2019-03-07]
Gene Group (FlyBase)
GUSTATORY RECEPTORS -
The Gustatory receptors are a divergent group of (non-GPCR) seven-transmembrane chemoreceptors that are expressed in gustatory sensilla receptor neurons. They detect tastants (non-volatile compounds) via contact chemosensation. (Adapted from FBrf0208984).
Protein Function (UniProtKB)
Gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates. Plays a role in sustaining courtship behavior in males, possibly through the reception of a stimulating arrestant pheromone.
Gene Model and Products
Number of Transcripts
4
Number of Unique Polypeptides
4

Please see the JBrowse view of Dmel\Gr39a for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)
Isoform displayed:
Pfam protein domains
InterPro name
classification
start
end
Protein Domains (via SMART)
Isoform displayed:
SMART protein domains
InterPro name
classification
start
end
Comments on Gene Model

Gene model reviewed during 5.47

Sequence Ontology: Class of Gene
Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Assoc. CDS (aa)
FBtr0081511
1116
371
FBtr0081508
1119
372
FBtr0081509
1146
381
FBtr0081510
1146
381
Additional Transcript Data and Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
RefSeq ID
GenBank
FBpp0081039
42.4
371
9.25
FBpp0081036
42.8
372
9.83
FBpp0081037
44.5
381
10.17
FBpp0081038
44.6
381
9.99
Polypeptides with Identical Sequences

None of the polypeptides share 100% sequence identity.

Additional Polypeptide Data and Comments
Reported size (kDa)
Comments
External Data
Crossreferences
InterPro - A database of protein families, domains and functional sites
Linkouts
Sequences Consistent with the Gene Model
Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Gr39a using the Feature Mapper tool.

External Data
Crossreferences
Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
Linkouts
Expression Data
Expression Summary Ribbons
Colored tiles in ribbon indicate that expression data has been curated by FlyBase for that anatomical location. Colorless tiles indicate that there is no curated data for that location.
For complete stage-specific expression data, view the modENCODE Development RNA-Seq section under High-Throughput Expression below.
Transcript Expression
Additional Descriptive Data
Marker for
 
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
 
Subcellular Localization
CV Term
Evidence
References
Expression Deduced from Reporters
Stage
Tissue/Position (including subcellular localization)
Reference
S-type sensillum S0

Comment: isoform Gr39a-RA

S-type sensillum S1

Comment: isoform Gr39a-RA

S-type sensillum S3

Comment: isoform Gr39a-RA

S-type sensillum S4

Comment: isoform Gr39a-RA

S-type sensillum S5

Comment: isoform Gr39a-RA

S-type sensillum S6

Comment: isoform Gr39a-RA

S-type sensillum S7

Comment: isoform Gr39a-RA

S-type sensillum S10

Comment: isoform Gr39a-RA

S-type sensillum S11

Comment: isoform Gr39a-RA

S-type sensillum S12

Comment: isoform Gr39a-RA

I-type sensillum I3

Comment: isoform Gr39a-RA

I-type sensillum I4

Comment: isoform Gr39a-RA

I-type sensillum I5

Comment: isoform Gr39a-RA

I-type sensillum I6

Comment: isoform Gr39a-RA

I-type sensillum I7

Comment: isoform Gr39a-RA

I-type sensillum I8

Comment: isoform Gr39a-RA

I-type sensillum I9

Comment: isoform Gr39a-RA

I-type sensillum I10

Comment: isoform Gr39a-RA

S-type sensillum S0 | intense

Comment: isoform Gr39a-RA

S-type sensillum S1 | intense

Comment: isoform Gr39a-RA

S-type sensillum S3 | intense

Comment: isoform Gr39a-RA

S-type sensillum S4 | intense

Comment: isoform Gr39a-RA

S-type sensillum S5 | intense

Comment: isoform Gr39a-RA

S-type sensillum S6 | intense

Comment: isoform Gr39a-RA

S-type sensillum S7 | intense

Comment: isoform Gr39a-RA

S-type sensillum S10 | intense

Comment: isoform Gr39a-RA

S-type sensillum S11 | intense

Comment: isoform Gr39a-RA

S-type sensillum S12 | intense

Comment: isoform Gr39a-RA

I-type sensillum I3 | intense

Comment: isoform Gr39a-RA

I-type sensillum I4 | intense

Comment: isoform Gr39a-RA

I-type sensillum I5 | intense

Comment: isoform Gr39a-RA

I-type sensillum I6 | intense

Comment: isoform Gr39a-RA

I-type sensillum I7 | intense

Comment: isoform Gr39a-RA

I-type sensillum I8 | intense

Comment: isoform Gr39a-RA

I-type sensillum I9 | intense

Comment: isoform Gr39a-RA

I-type sensillum I10 | intense

Comment: isoform Gr39a-RA

Reporter: P{Gr39a.b-GAL4.1}
Stage
Tissue/Position (including subcellular localization)
Reference
Stage
Tissue/Position (including subcellular localization)
Reference
High-Throughput Expression Data
Associated Tools

GBrowse - Visual display of RNA-Seq signals

View Dmel\Gr39a in GBrowse 2
RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region
Reference
See Gelbart and Emmert, 2013 for analysis details and data files for all genes.
Developmental Proteome: Life Cycle
Developmental Proteome: Embryogenesis
External Data and Images
Alleles, Insertions, Transgenic Constructs, and Aberrations
Classical and Insertion Alleles ( 9 )
For All Classical and Insertion Alleles Show
 
Other relevant insertions
Transgenic Constructs ( 5 )
For All Alleles Carried on Transgenic Constructs Show
Transgenic constructs containing/affecting coding region of Gr39a
Transgenic constructs containing regulatory region of Gr39a
Aberrations (Deficiencies and Duplications) ( 9 )
Phenotypes
Orthologs
Human Orthologs (via DIOPT v8.0)
Homo sapiens (Human) (0)
No records found.
Model Organism Orthologs (via DIOPT v8.0)
Mus musculus (laboratory mouse) (0)
No records found.
Rattus norvegicus (Norway rat) (0)
No records found.
Xenopus tropicalis (Western clawed frog) (0)
No records found.
Danio rerio (Zebrafish) (0)
No records found.
Caenorhabditis elegans (Nematode, roundworm) (3)
2 of 15
Yes
No
1 of 15
No
Yes
1 of 15
No
No
Arabidopsis thaliana (thale-cress) (0)
No records found.
Saccharomyces cerevisiae (Brewer's yeast) (0)
No records found.
Schizosaccharomyces pombe (Fission yeast) (0)
No records found.
Ortholog(s) in Drosophila Species (via OrthoDB v9.1) ( EOG09190D5U )
Organism
Common Name
Gene
AAA Syntenic Ortholog
Multiple Dmel Genes in this Orthologous Group
Drosophila simulans
Drosophila yakuba
Drosophila virilis
Orthologs in non-Drosophila Dipterans (via OrthoDB v9.1) ( EOG091508LB )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Musca domestica
House fly
Orthologs in non-Dipteran Insects (via OrthoDB v9.1) ( EOG090W09B3 )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Tribolium castaneum
Red flour beetle
Orthologs in non-Insect Arthropods (via OrthoDB v9.1) ( None identified )
No non-Insect Arthropod orthologies identified
Orthologs in non-Arthropod Metazoa (via OrthoDB v9.1) ( None identified )
No non-Arthropod Metazoa orthologies identified
Paralogs
Paralogs (via DIOPT v8.0)
Drosophila melanogaster (Fruit fly) (47)
2 of 10
2 of 10
2 of 10
2 of 10
2 of 10
2 of 10
2 of 10
2 of 10
2 of 10
2 of 10
1 of 10
1 of 10
1 of 10
1 of 10
1 of 10
1 of 10
1 of 10
1 of 10
1 of 10
1 of 10
1 of 10
1 of 10
1 of 10
1 of 10
1 of 10
1 of 10
1 of 10
1 of 10
1 of 10
1 of 10
1 of 10
1 of 10
1 of 10
1 of 10
1 of 10
1 of 10
1 of 10
1 of 10
1 of 10
1 of 10
1 of 10
1 of 10
1 of 10
1 of 10
1 of 10
1 of 10
1 of 10
Human Disease Associations
FlyBase Human Disease Model Reports
    Disease Model Summary Ribbon
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Evidence
    References
    Potential Models Based on Orthology ( 0 )
    Human Ortholog
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Interaction
    References
    Disease Associations of Human Orthologs (via DIOPT v8.0 and OMIM)
    Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
    Homo sapiens (Human)
    Gene name
    Score
    OMIM
    OMIM Phenotype
    DO term
    Complementation?
    Transgene?
    Functional Complementation Data
    Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
    Interactions
    Summary of Physical Interactions
    esyN Network Diagram
    Interactions Browser
    Summary of Genetic Interactions
    esyN Network Diagram
    Starting gene(s)
    Interaction type
    Interacting gene(s)
    Reference
    Starting gene(s)
    Interaction type
    Interacting gene(s)
    Reference
    External Data
    Linkouts
    DroID - A comprehensive database of gene and protein interactions.
    MIST (protein-protein) - An integrated Molecular Interaction Database
    Pathways
    Signaling Pathways (FlyBase)
    Metabolic Pathways
    External Data
    Linkouts
    Genomic Location and Detailed Mapping Data
    Chromosome (arm)
    2L
    Recombination map
    2-54
    Cytogenetic map
    Sequence location
    2L:21,290,734..21,297,686 [+]
    FlyBase Computed Cytological Location
    Cytogenetic map
    Evidence for location
    39C1-39C1
    Left limit from in situ hybridisation (FBrf0067338) Right limit from in situ hybridisation (FBrf0067338); Limits computationally determined from genome sequence between P{lacW}l(2)k14505k14505&P{lacW}l(2)k05106k05106 and P{PZ}l(2)05095a05095a
    Experimentally Determined Cytological Location
    Cytogenetic map
    Notes
    References
    39C1-39C2
    (determined by in situ hybridisation)
    Experimentally Determined Recombination Data
    Location
    Left of (cM)
    Right of (cM)
    Notes
    Stocks and Reagents
    Stocks (7)
    Genomic Clones (19)
    cDNA Clones (0)
     

    Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

    cDNA clones, fully sequenced
    BDGP DGC clones
      Other clones
        Drosophila Genomics Resource Center cDNA clones

        For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

          cDNA Clones, End Sequenced (ESTs)
          BDGP DGC clones
            Other clones
              RNAi and Array Information
              Linkouts
              GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
              Antibody Information
              Laboratory Generated Antibodies
               
              Commercially Available Antibodies
               
              Other Information
              Relationship to Other Genes
              Source for database identify of
              Source for database merge of

              Source for merge of: Gr39a l(2)k05106

              Additional comments
              Other Comments

              New annotation (CG31622) in release 3 of the genome annotation.

              Origin and Etymology
              Discoverer
              Etymology
              Identification
              External Crossreferences and Linkouts ( 35 )
              Sequence Crossreferences
              NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
              GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
              GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
              RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.
              UniProt/Swiss-Prot - Manually annotated and reviewed records of protein sequence and functional information
              Other crossreferences
              Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
              GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
              iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)
              InterPro - A database of protein families, domains and functional sites
              KEGG Genes - Molecular building blocks of life in the genomic space.
              Linkouts
              DroID - A comprehensive database of gene and protein interactions.
              MIST (protein-protein) - An integrated Molecular Interaction Database
              Synonyms and Secondary IDs (31)
              Reported As
              Symbol Synonym
              GR39D.2
              Name Synonyms
              Gustatory receptor 39D.2
              Gustatory receptor 39a
              lethal (2) k05106
              Secondary FlyBase IDs
              • FBgn0041244
              • FBgn0051622
              • FBgn0022191
              Datasets (0)
              Study focus (0)
              Experimental Role
              Project
              Project Type
              Title
              References (68)