Gene model reviewed during 5.50
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.56
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Pcf11 using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\Pcf11 in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
The gene symbol "Inr-a" has been changed to "Pcf11" to reflect the preferred usage in the literature and in order to reduce confusion with the "Inr-A" ("Inverse-regulator-Adh") gene symbol, from which it differed only by case.
Source for merge of l(2)k08015 anon-WO0118547.146 was sequence comparison ( date:051113 ).
dsRNA made from templates generated with primers directed against this gene.
Pcf11 inhibits transcription elongation by PolIIA under conditions that promote pausing.
RNAi generated by PCR using primers directed to this gene causes a cell growth and viability phenotype when assayed in Kc167 and S2R+ cells.
Area matching Drosophila EST AA978927. This EST has sequence similarity to human PCF11p homolgue.
The Inr-a regulatory gene interacts with the white locus via regulatory sequences.
Named 'Pcf11' after the yeast ortholog.