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FB2026_02
,
released June 18, 2026
radish, rad
rapidly evolving gene encoding a protein that contains multiple phosphorylation sites - required for anaesthesia resistent memory - can influence memory performance from minutes to hours after training - the Radish memory component does not scale with the stability of a memory trace
Please see the JBrowse view of Dmel\rsh for information on other features
To submit a correction to a gene model please use the Contact FlyBase form
AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Gene model reviewed during 5.41
Annotated transcripts do not represent all possible combinations of alternative exons and/or alternative promoters.
Gene model reviewed during 5.50
Low-frequency RNA-Seq exon junction(s) not annotated.
None of the polypeptides share 100% sequence identity.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\rsh using the Feature Mapper tool.
The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).
rad protein is expressed throughout the neuropil of adult brains and is particularly strong in the calyx, peduncle, and lobes of the mushroom bodies and the ellipsoid body of the central complex.
JBrowse - Visual display of RNA-Seq signals
View Dmel\rsh in JBrowse1-41
1-41.3
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
RNAi generated by PCR using primers directed to this gene causes a cell growth and viability phenotype when assayed in Kc167 and S2R+ cells.
Anaesthesia resistant memory is, though long term memory is not disrupted by mutation at rad.
Source for merge of: rad CG15720
Source for merge of: CG18646 CG4368
Source for merge of: rad CG42629
Annotations CG42628 and CG42629 merged as CG44424 in release 5.50 of the genome annotation. Merge based on RNA-seq junction and expression data.
The CG15720-RB transcript was created in release 5.1 of the genome annotation. This annotation contained sequences corresponding to the IP18538 cDNA clone (BT030283) at its 3' end, and was annotated as part of the CG15720 annotation (which corresponds to the rad locus). In release 5.22 of the genome annotation, the CG15720-RB transcript has been deleted, and sequences corresponding to the IP18538 cDNA clone (BT030283) have instead been joined to sequences from the CG18646 annotation, to form a new annotation, CG42629. The annotation corresponding to the rad locus has been renamed from CG15720 to CG42628 to avoid confusion and consists of a single transcript (CG42628-RA) in release 5.22 of the genome annotation.
The 'radish' complementation group does not correspond to CG42237 as previously reported in FBrf0174475.
Source for merge of CG18646 CG4368 was sequence comparison ( date:001216 ).
Source for identity of: rsh rad
The original gene name "radish" (rsh) was changed to "rsh GTPase activating protein" (rsh) to eliminate the potentially offensive association of "vegetable" gene names with human mental disability.
FlyBase curator comment: Renamed from 'rad' to 'rsh' to reflect the original symbol used for the 'radish' gene and the overwhelming preference in the literature since.
