slimb, ica, shv, shiva, β-TrCP
beta-transducin family Trp-Asp repeats family - subunit of a multi-protein complex that targets proteins for degradation by the ubiquitin-proteasome pathway - an important regulator of Wingless, Hedgehog and Dorsal pathways
Please see the JBrowse view of Dmel\slmb for information on other features
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AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Stop-codon suppression (UAA) postulated; FBrf0216884.
Gene model reviewed during 5.44
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.46
Tissue-specific extension of 3' UTRs observed during later stages (FBrf0218523, FBrf0219848); all variants may not be annotated
4.0, 3.0, 2.6 (northern blot)
2.154 (compiled cDNA)
510 (aa)
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\slmb using the Feature Mapper tool.
Comment: reported as procephalic ectoderm anlage
Comment: reported as procephalic ectoderm anlage
Comment: reported as procephalic ectoderm anlage
Comment: reported as procephalic ectoderm anlage
GBrowse - Visual display of RNA-Seq signals
View Dmel\slmb in GBrowse 2Maps to 3R.
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: slmb CG3412
Source for merge of: slmb CG3412
Source for merge of: slmb wel
Source for merge of: slmb BcDNA:GM02031
Source for merge of: slmb shv
Source for merge of: slmb ica
Source for merge of: slmb MENE(3R)-B
Source for merge of slmb CG3412 was sequence comparison ( date:000414 ).
Source for merge of slmb BcDNA:GM02031 was a shared cDNA ( date:030728 ).
dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology.
Isolated in an EMS screen for recessive mutations that alter normal adult patterning in somatic clones.
Strong alleles cause embryonic lethality while weak alleles cause larval and pupal lethality.
Isolated in a screen for mutations that modify fu phenotypes.
Identified in an adult mosaic screen for negative regulators of cell proliferation.
Given the name "pingiel", after one of Pavlov's dogs.