VCP, dVCP, p97, l(2)03775, Valosin-containing protein
AAA family ATPase, CDC48 subfamily - modulation of proteolytic degradation - Hedgehog pathway -Wingless pathway - dendritic pruning -motor neuron degeneration - ER stress response - maintenance of paternal chromosome integrity in the Drosophila zygote
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.46
Gene model reviewed during 5.52
3.2 (northern blot)
None of the polypeptides share 100% sequence identity.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\TER94 using the Feature Mapper tool.
TER94 transcripts are strongly expressed in nurse cells starting in stage 9-10 of oogenesis. Strong expression is also observed in developing ommatidia in the eye imaginal disc.
GBrowse - Visual display of RNA-Seq signalsView Dmel\TER94 in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for merge of: TER94 l(2)03775
Source for merge of: TER94 Apple
Source for merge of: TER94 l(2)46Ch
Source for merge of: TER94 l(2)46CFf l(2)46CFs
Source for merge of: Tera TER94
Source for merge of: TER94 l(2)46Db
The l(2)46Db complementation group corresponds to TER94, even though l(2)46Db shows a complex complementation pattern with other TER94 alleles.
TER94 inhibition interferes with class IV neuron dendrite pruning and class III neuron apoptosis during the pupal stage.
dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology.
Identification: approximately 3.3kb transcript identified during molecular analysis of the eve genomic region.
Identification: Physical interaction with bam protein in a yeast two hybrid assay.
A Drosophila homolog of CDC48, a protein that has been linked to vesicle fusion in yeast and vertebrate cells, isolated in a protein interaction screen showing interaction with bam.