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Citation
Sawamura, K. (2012). Chromatin evolution and molecular drive in speciation.  Int. J. Evol. Biol. 2012(): 301894.
FlyBase ID
FBrf0217029
Publication Type
Review
Abstract

Are there biological generalities that underlie hybrid sterility or inviability? Recently, around a dozen "speciation genes" have been identified mainly in Drosophila, and the biological functions of these genes are revealing molecular generalities. Major cases of hybrid sterility and inviability seem to result from chromatin evolution and molecular drive in speciation. Repetitive satellite DNAs within heterochromatin, especially at centromeres, evolve rapidly through molecular drive mechanisms (both meiotic and centromeric). Chromatin-binding proteins, therefore, must also evolve rapidly to maintain binding capability. As a result, chromatin binding proteins may not be able to interact with chromosomes from another species in a hybrid, causing hybrid sterility and inviability.

PubMed ID
PubMed Central ID
PMC3235502 (PMC) (EuropePMC)
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Secondary IDs
    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    Int. J. Evol. Biol.
    Title
    International journal of evolutionary biology
    ISBN/ISSN
    2090-052X 2090-8032
    Data From Reference
    Genes (11)