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Citation
Mair, W. (2013). Tipping the Energy Balance toward Longevity.  Cell Metab. 17(1): 5--6.
FlyBase ID
FBrf0220465
Publication Type
Note
Abstract

AMPK is a cellular energy sensor conserved across eukaryotes that in C. elegans prolongs life span and mimics dietary restriction. Stenesen and colleagues (2012) activate AMPK both directly and indirectly by altering AMP biosynthesis to slow aging in Drosophila, highlighting AMPK as a conserved life span modulator that links energy sensing to longevity.

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Related Publication(s)
Research paper

Adenosine Nucleotide Biosynthesis and AMPK Regulate Adult Life Span and Mediate the Longevity Benefit of Caloric Restriction in Flies.
Stenesen et al., 2013, Cell Metab. 17(1): 101--112 [FBrf0220505]

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Secondary IDs
    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    Cell Metab.
    Title
    Cell Metabolism
    Publication Year
    2005-
    ISBN/ISSN
    1550-4131
    Data From Reference