FB2025_01 , released February 20, 2025
Cell Line: Kc167
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General Information
Symbol
Kc167
Species
D. melanogaster
Feature type
cultured cell-line
FlyBase ID
FBtc0000001
Source
e/se
(Cherbas, 2008.11.12)
Tissue Source
embryo
(Cherbas et al., 1988)
Developmental Stage
dorsal closure stage
(Cherbas, 2008.11.12)
Lab of Origin

Goldschmidt-Clermont

(Cherbas et al., 1988)
Characterization
Sex
female (based on roX expression)
(Stoiber et al., 2016, Lee et al., 2014, Cherbas, 2008.10.15, Cherbas, 2008.11.12, Lynch and Maniatis, 1996)
Karyotype

approximately tetraploid

(Lee et al., 2014)

XO-haplo-IV pseudodiploid

(Cherbas, 2008.11.12)
Associated Genes (0)
    Integrated Constructs (0)
      Comments

      New stable cell line derived from this cell line: Stable Kc167 cell lines expressing either full-length Nup153 or a Nup153 mutant, which retains the N-terminal domain required for Nup107 recruitment while losing DNA binding and pore transport domains were generated.

      (Ryu et al., 2024)

      Cells were obtained from the laboratory of Matthieu Sanial.

      (Moniot-Perron et al., 2023)

      New stable cell line derived from this cell line: A stable mod(mdg4)67.2-GFP cell line was created (C-terminal GFP-tagged mod(mdg4)67.2).

      (Chen et al., 2022)

      Kc167 cells were obtained from the Harvard RNAi screening center (DRSC).

      (Chartschenko et al., 2021)

      Kc167 cells were obtained from the laboratory of Rachel Green.

      (Bag et al., 2021)

      New stable cell line derived from this cell line: A stable Kc167 cell line was created to be a "Notch reporter". It contains 24 MS2 stem loops and the coding sequence of LacZ in the endogenous N-regulated E(spl)mbeta-HLH gene in the context of a stable cell line expressing MCP-GFP (MCP-GFP is a MS2-binding protein).

      (Boukhatmi et al., 2020)

      New stable cell line derived from this cell line: Kc167 cells were stably transfected with Ras85D cDNAs modified to contain "common" or "rare" codons.

      (Sawyer et al., 2020)

      New stable cell line derived from this cell line: Stable Kc167 cell lines were generated expressing wild type brm or mutant brm (K804R).

      (Pillidge and Bray, 2019)

      Expression profiling by genome tiling array for this cell line (response to 5 hr ecdysone treatment) may be found at GEO: GSE16269 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE11280).

      (Stoiber et al., 2016)

      Expression of cell-type specific markers correlates with that of plasmatocytes.

      (Cherbas et al., 2011)

      Expression profiling by genome tiling array for this cell line may be found at GEO: GSE16273 (http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE16273).

      (Cherbas et al., 2011)

      RNA-Seq transcription profile for this cell line may be found at GEO: GSE15596 (http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE15596) and GEO: GSE18040 (http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE18040). See also the FlyBase collection report modENCODE_mRNA-Seq_cell.A (FBlc0000116) and FlyBase RNA-Seq GBrowse view.

      (Cherbas et al., 2011)

      Kc167 is one of the four lines chosen for extensive analysis by the modENCODE project.

      (Cherbas, 2008.11.12)

      Hemocyte-like gene expression, phagocytic, uniformly round, clump in sheets, ecdysone-responsive into adherent, bipolar spindle-shaped cells.

      (Ramadan et al., 2007)
      Parental Lines (1)
      Cloned from:
      Descendant Lines (17)
      External Stocks and Resources ( 3 )
      Crossreferences
      Cellosaurus - Cellosaurus is a knowledge resource on cell lines that attempts to describe all cell lines used in biomedical research.
      DGRC - Stock center for Drosophila cDNAs, vectors, and cell lines
      RRID - Research Resource Identification Portal
      Synonyms and Secondary IDs (11)
      Reported As
      Symbol Synonym
      CVCL_Z834
      (Bairoch, 2016)
      DGRC 1
      (Rosin et al., 2018)
      KC167
      (Westholm et al., 2014)
      Kc
      (Wensveen et al., 2024, Guo et al., 2016, Huisinga et al., 2016, Stoiber et al., 2016, Ross et al., 2013, Cherbas et al., 2011, Lynch and Maniatis, 1996)
      Kc (DGRC)
      (Wensveen et al., 2024)
      Kc 167
      (Niimi et al., 1999)
      Kc-167
      (Seridi et al., 2014)
      Kc167
      (Bamgbose and Tulin, 2024, Barton et al., 2024, Bar-Cohen et al., 2023, Davidson et al., 2023, Drees et al., 2023, Hodkinson et al., 2023, Klonaros et al., 2023, Moniot-Perron et al., 2023, Ray et al., 2023, Wooten et al., 2023, Ahmad and Henikoff, 2022, Bag et al., 2022, Bernués et al., 2022, Chen et al., 2022, Cheng et al., 2022, Faucillion et al., 2022, Gao et al., 2022, Garcia, 2022, Hu et al., 2022, Kaushal et al., 2022, Khyzha et al., 2022, Linnemannstöns et al., 2022, Mariyappa et al., 2022, Miao et al., 2022, Pandey and Chawla, 2022, Bag et al., 2021, Boldyreva et al., 2021, Chartschenko et al., 2021, Dib et al., 2021, Han et al., 2021, Kögler et al., 2021, Mariyappa et al., 2021, Pandey et al., 2021, Petrenko and Struhl, 2021, Shiomi et al., 2021, Soffers et al., 2021, Stephenson et al., 2021, Villa et al., 2021, Wang et al., 2021, Zykova et al., 2021, Boukhatmi et al., 2020, Duncan et al., 2020, Funikov et al., 2020, Gupta and Stocker, 2020, Lepesant et al., 2020, Liu and Hyeon, 2020, Luhur et al., 2020, Sawyer et al., 2020, Scacchetti et al., 2020, Shin et al., 2020, Verboon et al., 2020, Wooten et al., 2020, Yamada et al., 2020, Abdolhoseini et al., 2019, Albig et al., 2019, Albig et al., 2019, AlHaj Abed et al., 2019, Bag et al., 2019, Chorlay et al., 2019, Drees et al., 2019, Gutierrez-Perez et al., 2019, Haberle et al., 2019, Immarigeon et al., 2019, Lee et al., 2019, Luhur et al., 2019, Luzhin et al., 2019, Moschall et al., 2019, Pillidge and Bray, 2019, Porcelli et al., 2019, Ray et al., 2019, Rowley et al., 2019, Shao et al., 2019, Ulianov et al., 2019, Wang et al., 2019, Werthebach et al., 2019, Zacharioudaki et al., 2019, Acevedo et al., 2018, Baldi et al., 2018, Bell et al., 2018, Bi et al., 2018, Caridi et al., 2018, Fisher et al., 2018, Goto et al., 2018, Kim et al., 2018, Li et al., 2018, Mach et al., 2018, Mills et al., 2018, Nazer et al., 2018, Ong and Lin, 2018, Pindyurin et al., 2018, Rosin et al., 2018, Shrestha et al., 2018, Xun et al., 2018, Zhou et al., 2018, Chan et al., 2017, Chen and van Steensel, 2017, Chen et al., 2017, Cubeñas-Potts et al., 2017, El-Sharnouby et al., 2017, Franz et al., 2017, Franz et al., 2017, Ilyin et al., 2017, Kolkhof et al., 2017, Luhur et al., 2017, Marshall and Brand, 2017, Miller et al., 2017, Moraru et al., 2017, Mourad et al., 2017, Pamudurti et al., 2017, Schauer et al., 2017, Shao and Zeitlinger, 2017, Terriente-Félix et al., 2017, Thul et al., 2017, Urban et al., 2017, Vrettos et al., 2017, Yeh et al., 2017, Adrian et al., 2016, Ammeux et al., 2016, Bairoch, 2016, Beh et al., 2016, Boettiger et al., 2016, Bolin et al., 2016, Brueckner et al., 2016, Chlamydas et al., 2016, Fisher et al., 2016, Guo et al., 2016, Helenius et al., 2016, Hitrik et al., 2016, Li et al., 2016, Miettinen and Björklund, 2016, Pueyo et al., 2016, Senaratne et al., 2016, Stoiber et al., 2016, Tatomer et al., 2016, Toggweiler et al., 2016, Weasner et al., 2016, Wei et al., 2016, Zanotto-Filho et al., 2016, Kanoh et al., 2015, Liu et al., 2015, Ryu et al., 2015, Seeds et al., 2015, Spratford and Kumar, 2015, Verboon et al., 2015, Chen and Megraw, 2014, George et al., 2014, Lee et al., 2014, Reim et al., 2014, Thiel et al., 2013, Yang et al., 2013, Busayavalasa et al., 2012, Cherbas et al., 2011, Rose et al., 2011, Brombacher et al., 2009, Chang et al., 2008, Cherbas, 2008.10.15, Cherbas, 2008.11.12, Maloney et al., 2008, Martin-Granados et al., 2008, Stielow et al., 2008, Wang and Price, 2008, Langton et al., 2007, Li et al., 2007, Pindyurin et al., 2007, Ramadan et al., 2007, Moorman et al., 2006, Wagner et al., 2006, Sarbassov et al., 2005, Straight et al., 2005, Bruick and McKnight, 2001, Methot and Basler, 1999, Niimi et al., 1999, D'Avino et al., 1995, Bouhidel et al., 1994)
      Kc167-DRSC
      (Gozalo et al., 2020)
      Kc167
      (Baird et al., 2006, Bartscherer et al., 2006)
      RRID:CVCL_Z834
      (Bairoch, 2016)
      Name Synonyms
      Secondary FlyBase IDs
        References (442)