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General Information
Symbol
KDR
FlyBase ID
FBto0000322
Name
KD recombinase
Description
Description

KDR corresponds to the recombinase encoded by gene A from the Kluyveromyces lactis pKD1 plasmid. It specifically recognizes the KDRT target site, with recombination occurring between a pair of these sites. The recombination event results in genetic modification, the nature of which is influenced by the relative orientation (direct or inverted), location and composition of the two recognition sites. The types of possible modification include deletion of DNA, generation of chromosomal rearrangements and integration of DNA into the genome. KDR shows low toxicity in transgenic Drosophila (FBrf0214794).

Notes on Tool

KDR shows no recombinase activity towards the B2RT, B3RT, RSRT or FRT target sites in an in vivo excision assay.

External Crossreferences and Linkouts
Related experimental tools
Common gene of origin (1)
Compatible tools (1)
Transgenic Constructs
Insertions ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
Name Synonyms
KD recombinase
Secondary FlyBase IDs
    References (9)