UASt regulates expression of a mutated form of Vang carrying a mutation equivalent to M328T in human "VANGL1", and associated with neural tube defects. The protein is tagged with 3x Tag:FLAG. (FlyBase curator comment: the mutation in the Vang gene is given as V391T in FBrf0245453, however analysis of the release 6.34 annotated gene model indicates the change to be V388T).