FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term erythrokeratodermia variabilis ID (Ontology) DOID:0050467 (Human Disease)
Definition A skin disease that is characterized by areas of sharply demarcated, brown hyperkeratosis and has_material_basis_in mutations in genes encoding for connexin channels proteins in the epidermis.
Also Known As "Erythrokeratodermia Figurata Variabilis" ; "Greither Disease"
Comment
Links to External Ontologies
DO.org
Annotations
Records annotated with this term OR any of its CHILD TERMS
Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Alleles (FBal)  HUMAN_DISEASE_INTERACTIONS       4
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Alleles Genes
 erythrokeratodermia variabilis       4      3
 ameliorates | erythrokeratodermia variabilis       2       --
 exacerbates | erythrokeratodermia variabilis       1       --
 model of | erythrokeratodermia variabilis       1       --
Spanning Tree (Parents/Children)
Only view relationship: 
integumentary system disease
 |__skin disease_______
genetic disease        |
 |__monogenic disease__|
                       erythrokeratodermia variabilis  10 rec.
                        |__erythrokeratodermia variabilis et progressiva 1 2 rec.
                        |__erythrokeratodermia variabilis et progressiva 2
                        |__erythrokeratodermia variabilis et progressiva 3
                        |__erythrokeratodermia variabilis et progressiva 4 1 rec.
                        |__erythrokeratodermia variabilis et progressiva 5
                        |__erythrokeratodermia variabilis et progressiva 6 1 rec.
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Is a monogenic disease
skin disease
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Synonyms
  • "Erythrokeratodermia Figurata Variabilis" EXACT
    "Greither Disease" EXACT
Secondary IDs
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MESH:D056266
MIM:PS133200
NCI:C84696
ORDO:317
SNOMEDCT_US_2023_03_01:70041004
UMLS_CUI:C0265961
UMLS_CUI:C1851480