FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term Wieacker-Wolff syndrome ID (Ontology) DOID:0060815 (Human Disease)
Definition A syndromic X-linked intellectual disability characterized by severe intellectual deficit, microcephaly, exotropia, distal muscle wasting and low digital arches that has_material_basis_in variation in chromosomal region Xq13-q22.
Also Known As "MCS" ; "mental retardation, X-linked, syndromic 4" ; "mental retardation, X-linked, with congenital contractures and low fingertip arches" (for all, see Synonyms field below)
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 Genes
 Wieacker-Wolff syndrome       1
 for disease ribbon | Wieacker-Wolff syndrome       1
 model of | Wieacker-Wolff syndrome       1
Spanning Tree (Parents/Children)
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X-linked monogenic disease
 |__syndromic X-linked intellectual disability__
 |__X-linked recessive disease__________________|
syndromic intellectual disability               |
 |__syndromic X-linked intellectual disability__|
                                                Wieacker-Wolff syndrome  1 rec.
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Is a syndromic X-linked intellectual disability
X-linked recessive disease
Part of
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Synonyms
  • "MCS" EXACT OMO:0003012
    "mental retardation, X-linked, syndromic 4" EXACT
    "mental retardation, X-linked, with congenital contractures and low fingertip arches" EXACT
    "Miles-Carpenter syndrome" EXACT
    "MRXS4" EXACT OMO:0003012
    "WRWF" EXACT OMO:0003012
    "X-linked intellectual disability, Miles-Carpenter type" EXACT
Secondary IDs
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MIM:314580
ORDO:85283
UMLS_CUI:C1839735