FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
Help Close All Open All
General Information
Term immunodeficiency 98 ID (Ontology) DOID:0061068 (Human Disease)
Definition A combined T cell and B cell immunodeficiency that is characterized by recurrent infections associated with lymphoproliferation and autoinflammation in the first decade of life and that has_material_basis_in hemizygous mutation in the TLR8 gene on chromosome Xp22.
Also Known As "X-linked immunodeficiency 98 with autoinflammation"
Comment
Links to External Ontologies
DO.org
Annotations
Records annotated with this term OR any of its CHILD TERMS
    Results list data from multiple species. Click on a button above and use the 'Filter by species' options on the resulting HitList to retrieve species-specific data.
Records annotated with this exact term (annotations to child terms are NOT included)
No relevant records available
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Genes
 immunodeficiency 98       8
 for disease ribbon | immunodeficiency 98       8
 model of | immunodeficiency 98       8
Spanning Tree (Parents/Children)
Only view relationship: 
X-linked monogenic disease
 |__X-linked recessive disease___________________
combined immunodeficiency                        |
 |__combined T cell and B cell immunodeficiency__|
                                                 immunodeficiency 98  8 rec.
Spanning Tree View Settings
Parents/Children
View Depth
Show hierarchy levels: for parents, for children
hide Relationships
Is a X-linked recessive disease
combined T cell and B cell immunodeficiency
Part of
hide Synonyms & Secondary IDs
Synonyms
  • "X-linked immunodeficiency 98 with autoinflammation" EXACT
Secondary IDs
hide External Crossreferences & Linkouts
MIM:301078