FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term hereditary spastic paraplegia 88 ID (Ontology) DOID:0070457 (Human Disease)
Definition A hereditary spastic paraplegia characterized by infantile or early childhood onset of lower limb spasticity that slowly progresses with variable severity that has_material_basis_in heterozygous mutation in the KPNA3 gene on chromosome 13q14.2.
Also Known As "autosomal dominant spastic paraplegia 88" ; "SPG88"
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 Genes
 hereditary spastic paraplegia 88       2
 for disease ribbon | hereditary spastic paraplegia 88       2
 model of | hereditary spastic paraplegia 88       2
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autosomal genetic disease
 |__autosomal dominant disease_____
paraplegia                         |
 |__hereditary spastic paraplegia__|
                                   hereditary spastic paraplegia 88  2 rec.
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Is a autosomal dominant disease
hereditary spastic paraplegia
Part of
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Synonyms
  • "autosomal dominant spastic paraplegia 88" EXACT
    "SPG88" EXACT OMO:0003012
Secondary IDs
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MIM:620106