FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
Help Close All Open All
General Information
Term metabolic dysfunction-associated steatotic liver disease ID (Ontology) DOID:0080208 (Human Disease)
Definition A steatotic liver disease characterized by at least one of five specified cardiometabolic risk factors and no other discernible cause with normal to no alcohol use. The five cardiometabolic risk factors are: (1) higher than normal body mass index or waist circumference; (2) higher than normal serum glucose or glycated hemoglobin level, or type 2 diabetes; (3) higher than normal blood pressure or hypertensive treatment; (4) higher than normal plasma triglycerides or lipid lowering treatment; and (5) lower than normal plasma high-density lipoprotein cholesterol.
Also Known As "MAFLD" ; "MASLD" ; "metabolic dysfunction-associated fatty liver disease" (for all, see Synonyms field below)
Comment
Links to External Ontologies
DO.org
Annotations
Records annotated with this term OR any of its CHILD TERMS
Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Alleles (FBal)  HUMAN_DISEASE_INTERACTIONS       9
Human Disease Models (FBhh)  DOID       1
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Alleles Genes Human Disease Models
 metabolic dysfunction-associated steatotic liver disease       9      5      1
 model of | metabolic dysfunction-associated steatotic liver disease       9       --       --
Spanning Tree (Parents/Children)
Only view relationship:
liver disease__________
lipid storage disease__|
                       steatotic liver disease
                        |__metabolic dysfunction-associated steatotic liver disease  15 rec.
                            |__metabolic dysfunction-associated steatohepatitis
Spanning Tree View Settings
Parents/Children
View Depth
Show hierarchy levels: for parents, for children
hide Relationships
Is a steatotic liver disease
Part of
hide Synonyms & Secondary IDs
Synonyms
  • "MAFLD" EXACT OMO:0003012
    "MASLD" EXACT OMO:0003012
    "metabolic dysfunction-associated fatty liver disease" EXACT
    "metabolic dysfunction-related steatotic liver disease" EXACT
    "metabolic-associated fatty liver disease" EXACT
    "NAFL" NARROW OMO:0003012
    "NAFLD" EXACT OMO:0003012
    "non-alcoholic fatty liver" NARROW
    "non-alcoholic fatty liver disease" EXACT
    "nonalcoholic fatty liver" NARROW
    "nonalcoholic fatty liver disease" EXACT
Secondary IDs
hide External Crossreferences & Linkouts
MESH:D065626
MIM:613282
MIM:613387