FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
Help Close All Open All
General Information
Term acute myeloid leukemia with t(8;21); (q22; q22.1) ID (Ontology) DOID:0081093 (Human Disease)
Definition An acute myeloid leukemia associated with t(8;21)(q22;q22) resulting in RUNX1-RUNX1T1 fusion protein expression. The bone marrow and the peripheral blood show large myeloblasts with abundant basophilic cytoplasm, often containing azurophilic granules.
Also Known As "Acute Myeloid Leukemia with t(8;21); (q22; q22.1); RUNX1-RUNX1T1" ; "acute myeloid leukemia, t(8;21)(q22;q22)"
Comment
Links to External Ontologies
DO.org
Annotations
Records annotated with this term OR any of its CHILD TERMS
No relevant records available
Records annotated with this exact term (annotations to child terms are NOT included)
No relevant records available
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
No relevant statements available
Spanning Tree (Parents/Children)
Only view relationship: 
  myeloid leukemia
   |__acute myeloid leukemia
       |__acute myeloid leukemia with t(8;21); (q22; q22.1)
Spanning Tree View Settings
Parents/Children
View Depth
Show hierarchy levels: for parents, for children
hide Relationships
Is a acute myeloid leukemia
Part of
hide Synonyms & Secondary IDs
Synonyms
  • "Acute Myeloid Leukemia with t(8;21); (q22; q22.1); RUNX1-RUNX1T1" EXACT
    "acute myeloid leukemia, t(8;21)(q22;q22)" EXACT
Secondary IDs
hide External Crossreferences & Linkouts
ICDO:9896/3
NCI:C9288
UMLS_CUI:C1292774
UMLS_CUI:C2347540
UMLS_CUI:C5707782