FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term aromatase excess syndrome ID (Ontology) DOID:0090122 (Human Disease)
Definition A reproductive system disease characterized by increased extraglandular aromatization of steroids resulting in heterosexual precocity in males and isosexual precocity in females, and has_material_basis_in autosomal dominant inheritance of fusion of the aromatase gene (CYP19A1) with various partners, brought about by translocations and resulting in gain of function of the CYP19A1 gene.
Also Known As "AEXS" ; "familial hyperestrogenism" ; "hereditary prepubertal gynecomastia" (for all, see Synonyms field below)
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  disease of anatomical entity
   |__reproductive system disease
       |__aromatase excess syndrome
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Synonyms
  • "AEXS" EXACT OMO:0003012
    "familial hyperestrogenism" EXACT
    "hereditary prepubertal gynecomastia" EXACT
    "increased aromatase activity" EXACT
Secondary IDs
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GARD:12949
ICD10CM:E30.1
MIM:139300
ORDO:178345