FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term autoimmune lymphoproliferative syndrome type 2B ID (Ontology) DOID:0110116 (Human Disease)
Definition An autoimmune lymphoproliferative syndrome that has_material_basis_in homozygous mutation in the CASP8 gene on chromosome 2q33.
Also Known As "ALPS with recurrent viral infections" ; "ALPS2B" ; "autoimmune lymphoproliferative syndrome type IIB" (for all, see Synonyms field below)
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 Genes
 autoimmune lymphoproliferative syndrome type 2B       2
 for disease ribbon | autoimmune lymphoproliferative syndrome type 2B       2
 model of | autoimmune lymphoproliferative syndrome type 2B       2
Spanning Tree (Parents/Children)
Only view relationship: 
autosomal genetic disease
 |__autosomal recessive disease______________
hypersensitivity reaction type IV disease    |
 |__autoimmune lymphoproliferative syndrome__|
                                             autoimmune lymphoproliferative syndrome type 2B  2 rec.
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Is a autosomal recessive disease
autoimmune lymphoproliferative syndrome
Part of
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Synonyms
  • "ALPS with recurrent viral infections" EXACT
    "ALPS2B" EXACT OMO:0003012
    "autoimmune lymphoproliferative syndrome type IIB" EXACT
    "autoimmune lymphoproliferative syndrome with recurrent viral infections" EXACT
    "Caspase 8 deficiency" EXACT
    "Caspase 8 deficiency syndrome" EXACT
    "Caspase eight deficiency state" EXACT
    "CEDS" EXACT OMO:0003012
Secondary IDs
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ICD10CM:D47.9
MIM:607271
ORDO:275517