FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term CADASIL 2 ID (Ontology) DOID:0111036 (Human Disease)
Definition A CADASIL characterized by stroke, transient ischemic attacks, cognitive impairment, dementia, balance impairment, gait disturbance, headaches, and/or seizures associated with early confluent or confluent diffuse white matter hyperintensities that has_material_basis_in heterozygous mutation in the HTRA1 gene on chromosome 10q26.
Also Known As "autosomal dominant cerebral arteriopathy with subcortical infarcts and leukoencephalopathy type 2"
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 Genes
 CADASIL 2       1
 for disease ribbon | CADASIL 2       1
 model of | CADASIL 2       1
Spanning Tree (Parents/Children)
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autosomal genetic disease
 |__autosomal dominant disease__
leukodystrophy                  |
 |__CADASIL_____________________|
                                CADASIL 2  1 rec.
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Is a autosomal dominant disease
CADASIL
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Synonyms
  • "autosomal dominant cerebral arteriopathy with subcortical infarcts and leukoencephalopathy type 2" EXACT
Secondary IDs
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ICD10CM:F01.1
MIM:616779