FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term postural orthostatic tachycardia syndrome ID (Ontology) DOID:0111154 (Human Disease)
Definition A heart conduction disease characterized by orthostatic intolerance that has_material_basis_in heterozygous mutation in the SLC6A2 gene on chromosome 16q12.2.
Also Known As "familial orthostatic tachycardia due to norepinephrine transporter deficiency" ; "irritable heart" ; "mitral valve prolapse syndrome" (for all, see Synonyms field below)
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 Genes
 postural orthostatic tachycardia syndrome       2
 for disease ribbon | postural orthostatic tachycardia syndrome       2
 model of | postural orthostatic tachycardia syndrome       2
Spanning Tree (Parents/Children)
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heart disease
 |__heart conduction disease__
genetic disease               |
 |__monogenic disease_________|
                              postural orthostatic tachycardia syndrome  2 rec.
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Is a monogenic disease
heart conduction disease
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Synonyms
  • "familial orthostatic tachycardia due to norepinephrine transporter deficiency" EXACT
    "irritable heart" EXACT
    "mitral valve prolapse syndrome" EXACT
    "orhtostatic intolerance" EXACT
    "orthostatic intolerance due to NET deficiency" EXACT
    "postural tachycardia syndrome due to NET deficiency" EXACT
    "soldiers heart" EXACT
Secondary IDs
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GARD:9597
ICD10CM:I95.1
MESH:D054972
MIM:604715
ORDO:443236