FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term frontotemporal dementia and/or amyotrophic lateral sclerosis 7 ID (Ontology) DOID:0111227 (Human Disease)
Definition A frontotemporal dementia and/or amyotrophic lateral sclerosis that has_material_basis_in heterozygous mutation in CHMP2B on 3p11.2.
Also Known As "ALS17" ; "AMYOTROPHIC LATERAL SCLEROSIS" ; "AMYOTROPHIC LATERAL SCLEROSIS 17 (FORMERLY)" (for all, see Synonyms field below)
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DO.org
Annotations
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Data Class Field Records
Alleles (FBal)  HUMAN_DISEASE_INTERACTIONS      26
Human Disease Models (FBhh)  DOID       1
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Relevant FlyBase reports
 Alleles Genes Human Disease Models
 frontotemporal dementia and/or amyotrophic lateral sclerosis 7      26     14      1
 ameliorates | frontotemporal dementia and/or amyotrophic lateral sclerosis 7       5       --       --
 exacerbates | frontotemporal dementia and/or amyotrophic lateral sclerosis 7      18       --       --
 for disease ribbon | frontotemporal dementia and/or amyotrophic lateral sclerosis 7       --       1       --
 model of | frontotemporal dementia and/or amyotrophic lateral sclerosis 7       3      1       --
Spanning Tree (Parents/Children)
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dementia
 |__frontotemporal dementia________
motor neuron disease               |
 |__amyotrophic lateral sclerosis__|
brain disease                      |
 |__frontotemporal dementia________|
                                   frontotemporal dementia and/or amyotrophic lateral sclerosis 7  41 rec.
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Is a amyotrophic lateral sclerosis
frontotemporal dementia
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Synonyms
  • "ALS17" EXACT OMO:0003012
    "AMYOTROPHIC LATERAL SCLEROSIS" EXACT
    "AMYOTROPHIC LATERAL SCLEROSIS 17 (FORMERLY)" EXACT
    "amyotrophic lateral sclerosis type 17" EXACT
    "CHMP2B-RELATED" EXACT
    "CHMP2B-related frontotemporal dementia" EXACT
    "chromosome 3-linked frontotemporal dementia" EXACT
    "FRONTOTEMPORAL DEMENTIA" EXACT
    "FTD3" EXACT OMO:0003012
    "FTDALS7" EXACT OMO:0003012
Secondary IDs
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MESH:C579991
MIM:600795