FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term aminoglycoside-induced deafness ID (Ontology) DOID:0111734 (Human Disease)
Definition A drug-induced hearing loss characterized by hearing loss induced by therapeutic doses of aminoglycoside antibiotics that has_material_basis_in mutation in the mitochondrial genes MTRNR1 or MTCO1 in combination with homozygous mutation in TRMU on chromosome 22q13.31.
Also Known As "streptomycin ototoxicity" ; "streptomycin-induced deafness"
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 Genes
 aminoglycoside-induced deafness       1
 for disease ribbon | aminoglycoside-induced deafness       1
 model of | aminoglycoside-induced deafness       1
Spanning Tree (Parents/Children)
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  nonsyndromic deafness
   |__drug-induced hearing loss
       |__aminoglycoside-induced deafness  1 rec.
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Is a drug-induced hearing loss
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Synonyms
  • "streptomycin ototoxicity" EXACT
    "streptomycin-induced deafness" EXACT
Secondary IDs
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MIM:580000